(Q40923022)

24 September 2017

1 reference

title

Xenobiotic metabolism in brain (English)

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24 September 2017

Ravindranath V

1

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24 September 2017

Boyd MR

series ordinal

2

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24 September 2017

language of work or name

English

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publication date

1 January 1995

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24 September 2017

published in

Drug Metabolism Reviews

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24 September 2017

volume

27

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24 September 2017

issue

3

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24 September 2017

page(s)

419-448

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Biochemical mechanisms in chemical-induced lung injury: roles of metabolic activation

24 September 2017

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21 January 2018

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Effects of iproniazid and tranylcypromine of the half-life of N,N-dimethyltryptamine in rat brain and liver

21 January 2018

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Behavioral effects and metabolic fate of N,N-dimethyltryptamine in mice pretreated with β-diethylaminoethyl-diphenylpropylacetate (SKF 525-A), iproniazid and chlorpromazine

21 January 2018

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Chronic parkinsonism secondary to intravenous injection of meperidine analogues

21 January 2018

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A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

21 January 2018

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Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds

21 January 2018

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Flavin-containing monooxygenases: catalytic mechanism and substrate specificities

21 January 2018

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Rabbit lung flavin-containing monooxygenase is immunochemically and catalytically distinct from the liver enzyme

21 January 2018

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Molecular cloning of the flavin-containing monooxygenase (form II) cDNA from adult human liver

21 January 2018

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The mammalian flavin-containing monooxygenases: molecular characterization and regulation of expression

21 January 2018

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Microsomal flavin-containing monooxygenase activity in rat corpus striatum.

21 January 2018

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Presence of flavin-containing monooxygenase in rat brain

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602539508998330

Flavin-containing monooxygenase mediated metabolism of psychoactive drugs by human brain microsomes

21 January 2018

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The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature

21 January 2018

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N-demethylation of morphine in rat brain is localised in sites with high opiate receptor content

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602539508998330

Catechol estrogen-forming enzyme of brain: demonstration of a cytochrome p450 monooxygenase

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602539508998330

On the occurrence of cytochrome P-450 and aryl hydrocarbon hydroxylase activity in rat brain

21 January 2018

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Cytochrome P-450 and NADPH cytochrome C reductase in rat brain: Formation of catechols and reactive catechol metabolites

21 January 2018

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Subcellular distribution of cytochrome P-450 in the brain.

21 January 2018

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Regional distribution of cytochrome P-450 in the rat brain: spectral quantitation and contribution of P-450b,e, and P-450c,d.

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602539508998330

Preparation of brain microsomes with cytochrome P450 activity using calcium aggregation method.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Regional and subcellular distribution of cytochrome P-450-dependent drug metabolism in monkey brain: the olfactory bulb and the mitochondrial fraction have high levels of activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

The chronic administration of nicotine induces cytochrome P450 in rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

High activity of cytochrome P-450-linked aminopyrine N-demethylase in mouse brain microsomes, and associated sex-related difference

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Mestranol-induced hypertension: Characterization of cytochrome P-450 dependent catechol estrogen formation in brain microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Administration of testosterone alleviates the constitutive sex difference in rat brain cytochrome P-450.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Rat brain cytochromes P-450: catalytic, immunochemical properties and inducibility of multiple forms

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602539508998330

Differential effect of chronic nicotine administration on brain cytochrome P4501A1/2 and P4502E1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Distribution of cytochrome P450 activities towards alkoxyresorufin derivatives in rat brain regions, subcellular fractions and isolated cerebral microvessels

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Induction of brain cytochrome P-450IIE1 by chronic ethanol treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Metabolic activation of the serotonergic neurotoxin para-chloroamphetamine to chemically reactive intermediates by hepatic and brain microsomal preparations

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Biotransformation of the insecticide parathion by mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Cytochrome P-450 C21scc: one enzyme with two actions: hydroxylase and lyase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Neurosteroids: cytochrome P-450scc in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Neurosteroids: oligodendrocyte mitochondria convert cholesterol to pregnenolone

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Brain cytochrome P450 and testosterone metabolism by rat brain subcellular fractions: presence of cytochrome P450 3A immunoreactive protein in rat brain mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor

21 January 2018

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Asymmetry of brain aromatase activity: region- and sex-specific developmental patterns

21 January 2018

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Aromatization and 19-hydroxylation of androgens by rat brain cytochrome P-450.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Role of arachidonic acid or its metabolites in growth-hormone-releasing factor-induced release of somatostatin from the median eminence.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Brain synthesis and cerebrovascular action of epoxygenase metabolites of arachidonic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Lipoxygenation in rat brain?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Quantitation of mRNAs specific for the mixed-function oxidase system in rat liver and extrahepatic tissues during development

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Brain cytochromes P-450 are responsive to phenobarbital and tricyclic amines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Expression analysis of the mixed function oxidase system in rat brain by the polymerase chain reaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Immunohistochemical localization of cytochrome P-450 in the rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Regional distribution of ethanol-inducible cytochrome P450 IIE1 in the rat central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

MPTP, the neurotoxin inducing Parkinson's disease, is a potent competitive inhibitor of human and rat cytochrome P450 isozymes (P450bufI, P450db1) catalyzing debrisoquine 4-hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

A novel P450 expressed at the high level in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

The rat P450 IID subfamily: complete sequences of four closely linked genes and evidence that gene conversions maintained sequence homogeneity at the heme-binding region of the cytochrome P450 active site

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

The dopamine transporter and cytochrome P45OIID1 (debrisoquine 4-hydroxylase) in brain: resolution and identification of two distinct [3H]GBR-12935 binding proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Identification of cytochromes P450 1A2, 2A1, 2C7, 2E1 in rat glioma C6 cell line by RT-PCR and specific restriction enzyme digestion

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Inducibility of rat brain drug-metabolizing enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

First evidence of cytochrome P-450 induction in the mouse brain by phenytoin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Effect of ethanol on cytochrome P450 in the rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Identification of the major cytochrome P450s of subfamily 2C that are expressed in brain of female rats and in olfactory lobes of ethanol treated male rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Immunohistochemical localization of cytochrome P-450 in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Mapping of phenytoin-inducible cytochrome P450 immunoreactivity in the mouse central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Low glutathione levels in brain regions of aged rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Cytochrome P-450 dependent monooxygenases in neuronal and glial cells: inducibility and specificity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Brain lesions in alcoholics. A neuropathological study with clinical correlations.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Microsomal cytochrome P450 in human brain regions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Xenobiotic metabolism in human brain--presence of cytochrome P-450 and associated mono-oxygenases.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Subcellular localization of cytochrome P450, and activities of several enzymes responsible for drug metabolism in the human brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

NADPH cytochrome P-450 reductase in rat, mouse and human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Partial purification of cytochrome P450 from rat brain and demonstration of estradiol hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Reconstitution of the brain mixed function oxidase system: purification of NADPH-cytochrome P450 reductase and partial purification of cytochrome P450 from whole rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Characterization of a phenobarbital-inducible cytochrome P-450, NADPH-cytochrome P-450 reductase and reconstituted cytochrome P-450 mono-oxygenase system from rat brain. Evidence for constitutive presence in rat and human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Purification of multiple forms of cytochrome P450 from a human brain and reconstitution of catalytic activities.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

A new aspect of the protective functions of the blood-brain barrier: activities of four drug-metabolizing enzymes in isolated rat brain microvessels

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Is the sigma opiate receptor a proadifen-sensitive subform of cytochrome P-450?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

SKF 525-A and cytochrome P-450 ligands inhibit with high affinity the binding of [3H]dextromethorpan and σ ligands to guinea pig brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Differential effects of cytochrome P-450 induction on ligand binding to sigma receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Quantitative measurement of cerebral cytochrome P-450 by second derivative spectrophotometry

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Ethoxyresorufin O-deethylase activity in rat brain subcellular fractions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Brain mitochondrial cytochrome P-450scc: Spectral and catalytic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

Evidence for the Clara cell as a site of cytochrome P450-dependent mixed-function oxidase activity in lung

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602539508998330

10.3109/03602539508998330

21 January 2018

Identifiers

DOI

1 reference

24 September 2017

1 reference