(Q40980593)

English

HIF-1α and PFKFB3 Mediate a Tight Relationship Between Proinflammatory Activation and Anerobic Metabolism in Atherosclerotic Macrophages

scientific article published on 16 April 2015

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

HIF-1α and PFKFB3 Mediate a Tight Relationship Between Proinflammatory Activation and Anerobic Metabolism in Atherosclerotic Macrophages (English)

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

atherosclerosis

1 reference

based on heuristic

inferred from title

José Antonio Enríquez

9

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25882065%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

María Pimentel-Santillana

4

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25882065%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

7

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9 June 2020

12

object named as

Ramón Bartrons

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9 June 2020

author name string

Ahmed Tawakol

1

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9 June 2020

Parmanand Singh

2

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9 June 2020

Marina Mojena

3

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9 June 2020

Hamed Emami

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25882065%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Megan MacNabb

6

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9 June 2020

Jagat Narula

8

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9 June 2020

Paqui G Través

10

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9 June 2020

María Fernández-Velasco

11

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9 June 2020

Paloma Martín-Sanz

13

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25882065%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Zahi A Fayad

14

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9 June 2020

Alberto Tejedor

15

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9 June 2020

Lisardo Boscá

16

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9 June 2020

language of work or name

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publication date

16 April 2015

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25 September 2017

Arteriosclerosis, Thrombosis, and Vascular Biology

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25882065%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

35

1 reference

Europe PubMed Central

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9 June 2020

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25882065%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1463-1471

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25882065%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Macrophages in atherosclerosis: a dynamic balance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441599

25 September 2017

Characterization of resident B cells of vascular walls in human atherosclerotic patients.

1 reference

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25 September 2017

Local proliferation dominates lesional macrophage accumulation in atherosclerosis

1 reference

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25 September 2017

Role of PFKFB3-driven glycolysis in vessel sprouting

1 reference

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25 September 2017

A cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells.

1 reference

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25 September 2017

Nontransformed, GM-CSF-dependent macrophage lines are a unique model to study tissue macrophage functions.

1 reference

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25 September 2017

Targeting 6-phosphofructo-2-kinase (PFKFB3) as a therapeutic strategy against cancer

1 reference

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25 September 2017

Hypoxia induces netrin-1 and Unc5b in atherosclerotic plaques: mechanism for macrophage retention and survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441599

25 September 2017

Hypoxia in murine atherosclerotic plaques and its adverse effects on macrophages

1 reference

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25 September 2017

Leukocyte behavior in atherosclerosis, myocardial infarction, and heart failure

1 reference

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25 September 2017

Executive summary: heart disease and stroke statistics--2013 update: a report from the American Heart Association

1 reference

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25 September 2017

Small molecule inhibition of 6-phosphofructo-2-kinase suppresses t cell activation

1 reference

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25 September 2017

Molecular basis for the differential use of glucose and glutamine in cell proliferation as revealed by synchronized HeLa cells.

1 reference

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25 September 2017

Block copolymer micelles for controlled delivery of glycolytic enzyme inhibitors

1 reference

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25 September 2017

Hypoxia-inducible factor-2α regulates GM-CSF-derived soluble vascular endothelial growth factor receptor 1 production from macrophages and inhibits tumor growth and angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441599

25 September 2017

Macrophages in the pathogenesis of atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441599

25 September 2017

Hypoxia and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441599

25 September 2017

Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441599

25 September 2017

Macrophage death and defective inflammation resolution in atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441599

25 September 2017

THE METABOLISM OF TUMORS IN THE BODY

1 reference

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25 September 2017

Regulation of glucose metabolism by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases in cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441599

25 September 2017

Novel concepts in atherogenesis: angiogenesis and hypoxia in atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441599

25 September 2017

Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441599

25 September 2017

Phosphorylation of the 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase/PFKFB3 family of glycolytic regulators in human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441599

25 September 2017

Why do cancers have high aerobic glycolysis?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441599

25 September 2017

6-Phosphofructo-2-kinase (pfkfb3) gene promoter contains hypoxia-inducible factor-1 binding sites necessary for transactivation in response to hypoxia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441599

25 September 2017

HIF-1alpha is essential for myeloid cell-mediated inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441599

25 September 2017

Inflammation in atherosclerosis

1 reference

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25 September 2017

Protein kinase Cepsilon is required for macrophage activation and defense against bacterial infection

1 reference

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25 September 2017

Distinct domains of the human granulocyte-macrophage colony-stimulating factor receptor alpha subunit mediate activation of Jak/Stat signaling and differentiation

1 reference

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25 September 2017

Measurement of cytokine secretion, intracellular protein expression, and mRNA in resting and stimulated peripheral blood mononuclear cells.

1 reference

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25 September 2017

Macrophage oxygen-dependent antimicrobial activity. III. Enhanced oxidative metabolism as an expression of macrophage activation

1 reference

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25 September 2017

Relevance of the MEK/ERK signaling pathway in the metabolism of activated macrophages: a metabolomic approach.

1 reference

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17 June 2018

The regulation of the human tumor necrosis factor alpha promoter region in macrophage, T cell, and B cell lines

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17 June 2018

Chronic hypoxia leads to a glycolytic phenotype and suppressed HIF-2 signaling in PC12 cells.

1 reference

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19 August 2018

Synergism between curdlan and GM-CSF confers a strong inflammatory signature to dendritic cells.

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19 August 2018

Hypoxia-specific GM-CSF-overexpressing neural stem cells improve graft survival and functional recovery in spinal cord injury

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19 August 2018

Hypoxia but not inflammation augments glucose uptake in human macrophages: Implications for imaging atherosclerosis with 18fluorine-labeled 2-deoxy-D-glucose positron emission tomography.

1 reference

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19 August 2018

Hypoxia prolongs monocyte/macrophage survival and enhanced glycolysis is associated with their maturation under aerobic conditions.

1 reference

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1 reference

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19 August 2018

PFKFB3 gene silencing decreases glycolysis, induces cell-cycle delay and inhibits anchorage-independent growth in HeLa cells.

1 reference

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19 August 2018

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19 August 2018

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Substrate fate in activated macrophages: a comparison between innate, classic, and alternative activation

1 reference

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12 December 2020

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Relationships Between Oxidative Metabolism, Macrophage Activation, and Antilisterial Activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/25882065

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1161/ATVBAHA.115.305551

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25882065%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25882065%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25882065%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

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