(Q40998328)

25 September 2017

The effect of phenotypic outliers and non-normality on rare-variant association testing (English)

1 reference

25 September 2017

3

Suzanne M Leal

1 reference

25 September 2017

Paul L Auer

1

1 reference

25 September 2017

Alex P Reiner

series ordinal

2

1 reference

25 September 2017

language of work or name

1 reference

6 January 2016

1 reference

European Journal of Human Genetics

25 September 2017

1 reference

25 September 2017

24

1 reference

25 September 2017

8

1 reference

25 September 2017

1188-1194

1 reference

Rare variant association studies: considerations, challenges and opportunities

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4970685

Genetic studies of body mass index yield new insights for obesity biology

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4970685

Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4970685

Association of exome sequences with plasma C-reactive protein levels in >9000 participants

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4970685

Rare-variant association analysis: study designs and statistical tests

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4970685

Loss-of-function mutations in APOC3, triglycerides, and coronary disease

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4970685

Rare and low-frequency coding variants in CXCR2 and other genes are associated with hematological traits

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4970685

Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4970685

Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4970685

A variational Bayes discrete mixture test for rare variant association

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4970685

Testing for rare variant associations in the presence of missing data

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4970685

Linear regression in genetic association studies

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4970685

Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4970685

Optimal unified approach for rare-variant association testing with application to small-sample case-control whole-exome sequencing studies

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4970685

Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4970685

A general framework for detecting disease associations with rare variants in sequencing studies

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4970685

Bias due to two-stage residual-outcome regression analysis in genetic association studies

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4970685

Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT).

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4970685

Rare-variant association testing for sequencing data with the sequence kernel association test

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4970685

Pooled association tests for rare variants in exon-resequencing studies

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4970685

Finding the missing heritability of complex diseases

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4970685

An evaluation of statistical approaches to rare variant analysis in genetic association studies

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4970685

Rank-based inverse normal transformations are increasingly used, but are they merited?

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4970685

Methods for detecting associations with rare variants for common diseases: application to analysis of sequence data

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4970685

PLINK: a tool set for whole-genome association and population-based linkage analyses

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4970685

Design of the Women's Health Initiative clinical trial and observational study. The Women's Health Initiative Study Group

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4970685

Loss of power in two-stage residual-outcome regression analysis in genetic association studies

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4970685

Design of the Women’s Health Initiative Clinical Trial and Observational Study

19 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FEJHG.2015.270

An analysis of variance test for normality (complete samples)

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FEJHG.2015.270

21 January 2018

Identifiers

DOI

10.1038/EJHG.2015.270

1 reference

Dimensions Publication ID

25 September 2017

0 references

1 reference

25 September 2017

PubMed publication ID

26733287

1 reference