(Q41008812)

English

Reconstitution of insulin signaling pathways in rat 3Y1 cells lacking insulin receptor and insulin receptor substrate-1. Evidence that activation of Akt is insufficient for insulin-stimulated glycogen synthesis or glucose uptake in rat 3Y1 cells

scientific article published on September 1998

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scholarly article

1 reference

Europe PubMed Central

25 September 2017

Reconstitution of insulin signaling pathways in rat 3Y1 cells lacking insulin receptor and insulin receptor substrate-1. Evidence that activation of Akt is insufficient for insulin-stimulated glycogen synthesis or glucose uptake in rat 3Y1 cells (English)

1 reference

Europe PubMed Central

25 September 2017

1 reference

based on heuristic

inferred from title

author name string

Imanaka T

1

1 reference

Europe PubMed Central

25 September 2017

Hayashi H

2

1 reference

Europe PubMed Central

25 September 2017

Kishi K

3

1 reference

Europe PubMed Central

25 September 2017

Wang L

4

1 reference

Europe PubMed Central

25 September 2017

Ishii K

5

1 reference

Europe PubMed Central

25 September 2017

Hazeki O

6

1 reference

Europe PubMed Central

25 September 2017

Katada T

7

1 reference

Europe PubMed Central

25 September 2017

Ebina Y

8

1 reference

Europe PubMed Central

25 September 2017

language of work or name

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publication date

1 September 1998

1 reference

Europe PubMed Central

25 September 2017

number of pages

9

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inferred from page(s)

Journal of Biological Chemistry

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Europe PubMed Central

25 September 2017

273

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Europe PubMed Central

25 September 2017

25347-25355

1 reference

Europe PubMed Central

25 September 2017

39

1 reference

Europe PubMed Central

25 September 2017

Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

1 reference

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21 January 2018

Role of IRS-2 in insulin and cytokine signalling

1 reference

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21 January 2018

The 60-kDa phosphotyrosine protein in insulin-treated adipocytes is a new member of the insulin receptor substrate family.

1 reference

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21 January 2018

A novel 160-kDa phosphotyrosine protein in insulin-treated embryonic kidney cells is a new member of the insulin receptor substrate family

1 reference

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21 January 2018

A Grb2-associated docking protein in EGF- and insulin-receptor signalling

1 reference

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21 January 2018

A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

1 reference

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21 January 2018

IRS-1 activates phosphatidylinositol 3'-kinase by associating with src homology 2 domains of p85

1 reference

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21 January 2018

The function of GRB2 in linking the insulin receptor to Ras signaling pathways

1 reference

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21 January 2018

Nck associates with the SH2 domain-docking protein IRS-1 in insulin-stimulated cells

1 reference

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21 January 2018

Insulin-stimulated GLUT4 translocation is relevant to the phosphorylation of IRS-1 and the activity of PI3-kinase

1 reference

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21 January 2018

1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells

1 reference

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21 January 2018

Expression of a functional human insulin receptor from a cloned cDNA in Chinese hamster ovary cells

1 reference

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21 January 2018

Roles of insulin, guanosine 5'-[gamma-thio]triphosphate and phorbol 12-myristate 13-acetate in signalling pathways of GLUT4 translocation

1 reference

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21 January 2018

Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

1 reference

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21 January 2018

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

1 reference

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21 January 2018

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

1 reference

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21 January 2018

Activated phosphatidylinositol 3-kinase is sufficient to mediate actin rearrangement and GLUT4 translocation in 3T3-L1 adipocytes

1 reference

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21 January 2018

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.39.25347

21 January 2018

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.39.25347

21 January 2018

Possible domains responsible for intracellular targeting and insulin-dependent translocation of glucose transporter type 4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.39.25347

21 January 2018

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.39.25347

21 January 2018

Insulin stimulation of glycogen synthesis and glycogen synthase activity is blocked by wortmannin and rapamycin in 3T3-L1 adipocytes: evidence for the involvement of phosphoinositide 3-kinase and p70 ribosomal protein-S6 kinase

1 reference

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21 January 2018

Insulin action in cultured human myoblasts: contribution of different signalling pathways to regulation of glycogen synthesis.

1 reference

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21 January 2018

Microinjection of the SH2 domain of the 85-kilodalton subunit of phosphatidylinositol 3-kinase inhibits insulin-induced DNA synthesis and c-fos expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.39.25347

21 January 2018

Stimulation of protein synthesis, eukaryotic translation initiation factor 4E phosphorylation, and PHAS-I phosphorylation by insulin requires insulin receptor substrate 1 and phosphatidylinositol 3-kinase

1 reference

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21 January 2018

Differential signaling by insulin receptor substrate 1 (IRS-1) and IRS-2 in IRS-1-deficient cells

1 reference

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21 January 2018

IRS-1: essential for insulin- and IL-4-stimulated mitogenesis in hematopoietic cells

1 reference

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21 January 2018

Pertussis toxin inhibits the action of insulin-like growth factor-I.

1 reference

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21 January 2018

Signal transmission by the insulin-like growth factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.39.25347

21 January 2018

Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.39.25347

21 January 2018

Phosphatidylinositol-3-OH kinase as a direct target of Ras

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.39.25347

21 January 2018

New insights into the role and mechanism of glycogen synthase activation by insulin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.39.25347

21 January 2018

PTG, a protein phosphatase 1-binding protein with a role in glycogen metabolism

1 reference

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21 January 2018

Roles of 1-phosphatidylinositol 3-kinase and ras in regulating translocation of GLUT4 in transfected rat adipose cells

1 reference

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21 January 2018

The inability of phosphatidylinositol 3-kinase activation to stimulate GLUT4 translocation indicates additional signaling pathways are required for insulin-stimulated glucose uptake

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.39.25347

21 January 2018

Activation of mitogen-activated protein kinase and phosphatidylinositol 3'-kinase is not sufficient for the hormonal stimulation of glucose uptake, lipogenesis, or glycogen synthesis in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.39.25347

21 January 2018

Platelet-derived growth factor triggers translocation of the insulin-regulatable glucose transporter (type 4) predominantly through phosphatidylinositol 3-kinase binding sites on the receptor

1 reference

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21 January 2018

Binding to the platelet-derived growth factor receptor transiently activates the p85alpha-p110alpha phosphoinositide 3-kinase complex in vivo

1 reference

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21 January 2018

Overexpression of a constitutively active form of phosphatidylinositol 3-kinase is sufficient to promote Glut 4 translocation in adipocytes

1 reference

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21 January 2018

Differential effects of constitutively active phosphatidylinositol 3-kinase on glucose transport, glycogen synthase activity, and DNA synthesis in 3T3-L1 adipocytes

1 reference

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21 January 2018

Effect of the activation of phosphatidylinositol 3-kinase by a thiophosphotyrosine peptide on glucose transport in 3T3-L1 adipocytes

1 reference

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21 January 2018

Comparison of the effects of insulin, PDGF, interleukin-6, and interferon-gamma on glucose transport in 3T3-L1 cells: lack of cross-talk between tyrosine kinase receptors and JAK/STAT pathways

1 reference

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21 January 2018

Platelet-derived growth factor activates protein kinase C epsilon through redundant and independent signaling pathways involving phospholipase C gamma or phosphatidylinositol 3-kinase

1 reference

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21 January 2018

Activation of protein kinase C (alpha, beta, and zeta) by insulin in 3T3/L1 cells. Transfection studies suggest a role for PKC-zeta in glucose transport

1 reference

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21 January 2018

Phosphatidylinositol 3-kinase-dependent activation of protein kinase C-zeta in bacterial lipopolysaccharide-treated human monocytes

1 reference

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21 January 2018

Signaling by phosphoinositide-3,4,5-trisphosphate through proteins containing pleckstrin and Sec7 homology domains

1 reference

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21 January 2018

The specific protein phosphatase inhibitor okadaic acid differentially modulates insulin action

1 reference

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21 January 2018

Phosphoinositide 3-kinase as an upstream regulator of the small GTP-binding protein Rac in the insulin signaling of membrane ruffling

1 reference

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21 January 2018

G beta gamma subunits mediate mitogen-activated protein kinase activation by the tyrosine kinase insulin-like growth factor 1 receptor

1 reference

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21 January 2018

In vivo coupling of insulin-like growth factor II/mannose 6-phosphate receptor to heteromeric G proteins. Distinct roles of cytoplasmic domains and signal sequestration by the receptor

1 reference

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21 January 2018

Effects of overexpressing wild-type and mutant PDGF receptors on translocation of GLUT4 in transfected rat adipose cells

1 reference

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21 January 2018

Identifiers

10.1074/JBC.273.39.25347

1 reference

Europe PubMed Central

25 September 2017

1 reference

Europe PubMed Central

25 September 2017

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