(Q41086293)

26 September 2017

STIM1 dimers undergo unimolecular coupling to activate Orai1 channels (English)

1 reference

26 September 2017

6

1 reference

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3 June 2020

Youjun Wang

8

1 reference

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3 June 2020

Brad S. Rothberg

9

1 reference

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3 June 2020

author name string

Yandong Zhou

1

1 reference

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3 June 2020

Xizhuo Wang

2

1 reference

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3 June 2020

Xianming Wang

3

1 reference

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3 June 2020

Natalia A Loktionova

4

1 reference

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3 June 2020

Xiangyu Cai

5

1 reference

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3 June 2020

Erin Vrana

7

1 reference

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3 June 2020

Donald L Gill

10

1 reference

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3 June 2020

language of work or name

English

0 references

publication date

24 September 2015

1 reference

26 September 2017

Nature Communications

1 reference

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3 June 2020

volume

6

1 reference

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3 June 2020

page(s)

8395

1 reference

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Creative Commons Attribution 4.0 International

3 June 2020

copyright license

start time

24 September 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/ncomms9395

0 references

cites work

Inside-out Ca(2+) signalling prompted by STIM1 conformational switch.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

Missense mutation in immunodeficient patients shows the multifunctional roles of coiled-coil domain 3 (CC3) in STIM1 activation

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

Calcium signals tune the fidelity of transcriptional responses

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

Distinct spatial Ca2+ signatures selectively activate different NFAT transcription factor isoforms

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

Molecular biophysics of Orai store-operated Ca2+ channels.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

Potent functional uncoupling between STIM1 and Orai1 by dimeric 2-aminodiphenyl borinate analogs.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

Structural and functional mechanisms of CRAC channel regulation

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

Distinct Orai-coupling domains in STIM1 and STIM2 define the Orai-activating site

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

STIM1/Orai1 coiled-coil interplay in the regulation of store-operated calcium entry

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

Initial activation of STIM1, the regulator of store-operated calcium entry

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

Orai channel pore properties and gating by STIM: implications from the Orai crystal structure

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

Crystal Structure of the Calcium Release-Activated Calcium Channel Orai

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

STIM proteins: dynamic calcium signal transducers

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

Structural and mechanistic insights into the activation of Stromal interaction molecule 1 (STIM1)

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

CRAC channels drive digital activation and provide analog control and synergy to Ca(2+)-dependent gene regulation

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

Stoichiometric requirements for trapping and gating of Ca2+ release-activated Ca2+ (CRAC) channels by stromal interaction molecule 1 (STIM1).

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

Activation of STIM1-Orai1 involves an intramolecular switching mechanism.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

The calcium store sensor, STIM1, reciprocally controls Orai and CaV1.2 channels.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

Graded activation of CRAC channel by binding of different numbers of STIM1 to Orai1 subunits

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

Overlap extension PCR cloning: a simple and reliable way to create recombinant plasmids

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

Essential role for the CRAC activation domain in store-dependent oligomerization of STIM1.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

STIM1 gates the store-operated calcium channel ORAI1 in vitro

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

Properties of Orai1 mediated store-operated current depend on the expression levels of STIM1 and Orai1 proteins

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

STIM protein coupling in the activation of Orai channels.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

A Cytosolic Homomerization and a Modulatory Domain within STIM1 C Terminus Determine Coupling to ORAI1 Channels

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

SOAR and the polybasic STIM1 domains gate and regulate Orai channels

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

STIM1-Orai1 interactions and Orai1 conformational changes revealed by live-cell FRET microscopy

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

Mapping the interacting domains of STIM1 and Orai1 in Ca2+ release-activated Ca2+ channel activation

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

Orai1 and STIM reconstitute store-operated calcium channel function

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

Photobleaching-corrected FRET efficiency imaging of live cells

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

A coiled-coil clamp controls both conformation and clustering of stromal interaction molecule 1 (STIM1).

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

The C- and N-terminal STIM1 binding sites on Orai1 are required for both trapping and gating CRAC channels

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

The fluorescence protease protection (FPP) assay to determine protein localization and membrane topology.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598629

19 August 2018

Identifiers

DOI

10.1038/NCOMMS9395

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26399906%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

3 June 2020

ADS bibcode

2015NatCo...6.8395Z

0 references

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26399906%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

PubMed publication ID

26399906

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26399906%20AND%20SRC:MED&resulttype=core&format=json