Wikidata

(Q411462)

English

tylosin

chemical compound

  • Tylosin A
  • Tylocine
  • Tylan
In more languages

Statements

chemical structure
Tylosin structure.png
1,242 × 665; 19 KB
0 references
mass
915.519 dalton
1 reference
stated in
PubChem
PubChem CID
5280440
language of work or name
English
title
Tylosin (English)
retrieved
19 October 2016
chemical formula
C₄₆H₇₇NO₁₇
1 reference
stated in
PubChem
PubChem CID
5280440
language of work or name
English
title
Tylosin (English)
retrieved
19 November 2016
canonical SMILES
CCC1C(C=C(C=CC(=O)C(CC(C(C(C(CC(=O)O1)O)C)OC2C(C(C(C(O2)C)OC3CC(C(C(O3)C)O)(C)O)N(C)C)O)CC=O)C)C)COC4C(C(C(C(O4)C)O)OC)OC
1 reference
stated in
PubChem
PubChem CID
5280440
language of work or name
English
title
Tylosin (English)
retrieved
19 November 2016
isomeric SMILES
CC[C@@H]1[C@H](/C=C(/C=C/C(=O)[C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)C)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)O)N(C)C)O)CC=O)C)\C)CO[C@H]4[C@@H]([C@@H]([C@@H]([C@H](O4)C)O)OC)OC
1 reference
stated in
PubChem
PubChem CID
5280440
language of work or name
English
title
Tylosin (English)
retrieved
19 November 2016
found in taxon
Streptomyces fradiae
36 references
stated in
Molecular analysis of tlrD, an MLS resistance determinant from the tylosin producer, Streptomyces fradiae.
stated in
Cloning of tlrD, a fourth resistance gene, from the tylosin producer, Streptomyces fradiae
stated in
The tylosin producer, Streptomyces fradiae, contains a second valine dehydrogenase.
stated in
Valine dehydrogenase from Streptomyces fradiae: purification and properties
stated in
Impact of thioesterase activity on tylosin biosynthesis in Streptomyces fradiae.
stated in
Amino acid catabolism and antibiotic synthesis: valine is a source of precursors for macrolide biosynthesis in Streptomyces ambofaciens and Streptomyces fradiae
stated in
Characterization and targeted disruption of a glycosyltransferase gene in the tylosin producer, Streptomyces fradiae
stated in
Genetic engineering of aminodeoxyhexose biosynthesis in Streptomyces fradiae
stated in
Relationship between threonine dehydratase and biosynthesis of tylosin in Streptomyces fradiae
stated in
Homology between proteins controlling Streptomyces fradiae tylosin resistance and ATP-binding transport
stated in
The tylosin-biosynthetic genes of Streptomyces fradiae
stated in
The mycarose-biosynthetic genes of Streptomyces fradiae, producer of tylosin
stated in
Fatty acids and production of tylosin-like compounds in Streptomyces fradiae
stated in
Metabolic regulation in tylosin-producing Streptomyces fradiae: phosphate control of tylosin biosynthesis
stated in
Aspartate aminotransferase and tylosin biosynthesis in Streptomyces fradiae
stated in
Properties of Streptomyces fradiae Mutants Blocked in Biosynthesis of the Macrolide Antibiotic Tylosin
stated in
Production of tylosin in solid-state fermentation by Streptomyces fradiae NRRL-2702 and its gamma-irradiated mutant (gamma-1).
stated in
The tylosin resistance gene tlrB of Streptomyces fradiae encodes a methyltransferase that targets G748 in 23S rRNA.
stated in
Transposition mutagenesis in Streptomyces fradiae: identification of a neutral site for the stable insertion of DNA by transposon exchange
stated in
The effect of dissolved oxygen and aeration rate on antibiotic production of Streptomyces fradiae
stated in
The mycinose-biosynthetic genes of Streptomyces fradiae, producer of tylosin.
stated in
S-Adenosyl-L-methionine: macrocin O-methyltransferase activities in a series of Streptomyces fradiae mutants that produce different levels of the macrolide antibiotic tylosin
stated in
Synthesis of hydrolytic enzymes during production of tylosin by Streptomyces fradiae
stated in
Threonine dehydratases in different strains of Streptomyces fradiae
stated in
Kinetics of the repression of tylosin biosynthesis by ammonium ion in Streptomyces fradiae
stated in
Transcriptional attenuation control of the tylosin-resistance gene tlrA in Streptomyces fradiae
stated in
Characterization of mutations in regulatory genes of Tyl cluster leading to overexpression of tylosin in mutant γ-1 of Streptomyces fradiae NRRL-2702.
stated in
High frequency conjugal transfer of tylosin genes and amplifiable DNA in Streptomyces fradiae
stated in
Influence of dimethylsulfoxide on tylosin production in Streptomyces fradiae
stated in
Effects of rapessed oil on activity of methylmalonyl-CoA carboxyltransferase in culture of Streptomyces fradiae.
stated in
New tylosin analogs produced by mutants of Streptomyces fradiae
stated in
Biosynthesis of the macrolide antibiotic tylosin. Origin of the oxygen atoms in tylactone
stated in
Biosynthesis of Mycarose: Isolation and Characterization of Enzymes Involved in the C-2 Deoxygenation
stated in
The use of recombinant DNA techniques to study tylosin biosynthesis and resistance in Streptomyces fradiae
stated in
Branched-chain fatty acids produced by mutants of Streptomyces fradiae, putative precursors of the lactone ring of tylosin
stated in
Molecular Architecture of TylM1 from Streptomyces fradiae : An N , N -Dimethyltransferase Involved in the Production of dTDP- d -mycaminose,
Commons category
Tylosin
0 references

Identifiers

Reaxys registry number
4651020
1 reference
stated in
ChEBI
ChEBI ID
17658
language of work or name
English
title
tylosin (English)
retrieved
19 October 2016
HSDB ID
7022
1 reference
stated in
Hazardous Substances Data Bank
HSDB ID
7022
publication date
28 October 2019
title
TYLOSIN (English)
retrieved
10 May 2021
E number
E713
0 references
DrugBank ID
11475
1 reference
stated in
DrugBank
DrugBank ID
11475
retrieved
6 July 2021
quotation
CAS no.: 1401-69-0 (English)
title
Tylosin (English)
KEGG ID
D02490
1 reference
stated in
ChEBI
ChEBI ID
17658
language of work or name
English
title
tylosin (English)
retrieved
19 October 2016
PDB ligand ID
TYK
0 references
 
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