(Q41186044)

28 September 2017

title

IL-12 immunotherapy of Braf(V600E)-induced papillary thyroid cancer in a mouse model (English)

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28 September 2017

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papillary thyroid cancer

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Ranjit S Parhar

1

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28 September 2017

Minjing Zou

2

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28 September 2017

Futwan A Al-Mohanna

3

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28 September 2017

Essa Y Baitei

4

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28 September 2017

Abdullah M Assiri

5

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28 September 2017

Brian F Meyer

6

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28 September 2017

Yufei Shi

7

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28 September 2017

publication date

26 October 2015

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28 September 2017

published in

Laboratory Investigation

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28 September 2017

volume

96

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28 September 2017

issue

1

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28 September 2017

page(s)

89-97

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Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes

28 September 2017

cites work

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Human anaplastic thyroid carcinoma cells are sensitive to NK cell-mediated lysis via ULBP2/5/6 and chemoattract NK cells

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Gene therapy of cancer based on interleukin 12.

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TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance

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12 December 2020

Expression of endogenous oncogenic V600EB-raf induces proliferation and developmental defects in mice and transformation of primary fibroblasts

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12 December 2020

Tumour microenvironment: TGFbeta: the molecular Jekyll and Hyde of cancer

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12 December 2020

S100A4 (Mts1) gene overexpression is associated with invasion and metastasis of papillary thyroid carcinoma

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12 December 2020

BRAF mutation in thyroid cancer

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12 December 2020

Progression of BRAF-induced thyroid cancer is associated with epithelial-mesenchymal transition requiring concomitant MAP kinase and TGFβ signaling

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12 December 2020

Clinical review 128: Current approaches to primary therapy for papillary and follicular thyroid cancer

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A National Cancer Data Base report on 53,856 cases of thyroid carcinoma treated in the U.S., 1985-1995 [see commetns]

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12 December 2020

Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice

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12 December 2020

Interleukin 12 gene therapy of cancer by peritumoral injection of transduced autologous fibroblasts: outcome of a phase I study

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Effects of cytokine-mediated modulation of nm23 expression on the invasion and metastatic behavior of B16F10 melanoma cells.

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12 December 2020

Amelioration of B16F10 melanoma lung metastasis in mice by a combination therapy with indomethacin and interleukin 2.

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12 December 2020

Long-term outcome of 444 patients with distant metastases from papillary and follicular thyroid carcinoma: benefits and limits of radioiodine therapy.

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12 December 2020

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

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12 December 2020

Gene therapy of anaplastic thyroid carcinoma with a single-chain interleukin-12 fusion protein

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12 December 2020

Treatment with tyrosine kinase inhibitors for patients with differentiated thyroid cancer: the M. D. Anderson experience

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12 December 2020

Vaccination with IL-12 gene-modified autologous melanoma cells: preclinical results and a first clinical phase I study

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12 December 2020

Gene therapy with a single chain interleukin 12 fusion protein induces T cell-dependent protective immunity in a syngeneic model of murine neuroblastoma.

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12 December 2020

Tumor associated macrophages and neutrophils in tumor progression

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12 December 2020

Intratumoral injection of dendritic cells engineered to secrete interleukin-12 by recombinant adenovirus in patients with metastatic gastrointestinal carcinomas.

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12 December 2020

Mutationally activated BRAF(V600E) elicits papillary thyroid cancer in the adult mouse

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12 December 2020

Dual inhibition of mitogen-activated protein kinase kinase and mammalian target of rapamycin in differentiated and anaplastic thyroid cancer

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12 December 2020

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12 December 2020

Intratumoral injection of DNA encoding human interleukin 12 into patients with metastatic melanoma: clinical efficacy

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12 December 2020

Activity of subcutaneous interleukin-12 in AIDS-related Kaposi sarcoma

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12 December 2020

Targeted expression of BRAFV600E in thyroid cells of transgenic mice results in papillary thyroid cancers that undergo dedifferentiation.

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12 December 2020

Phase II trial of sorafenib in advanced thyroid cancer

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12 December 2020

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Interleukin-12: biological properties and clinical application

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Phase II study of celecoxib in metastatic differentiated thyroid carcinoma

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12 December 2020

Interleukin 12: still a promising candidate for tumor immunotherapy?

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12 December 2020

Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells

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12 December 2020

Elevated TGF-beta1 secretion and down-modulation of NKG2D underlies impaired NK cytotoxicity in cancer patients

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12 December 2020

Phase I evaluation of intravenous recombinant human interleukin 12 in patients with advanced malignancies

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12 December 2020

Recurrence of differentiated thyroid cancer in the elderly

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12 December 2020

Sorafenib: rays of hope in thyroid cancer.

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12 December 2020

Thyrocyte-specific expression of Cre recombinase in transgenic mice

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12 December 2020

10.1038/LABINVEST.2015.126

Identifiers

DOI

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28 September 2017

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