(Q41199353)

28 September 2017

The N-end rule pathway is mediated by a complex of the RING-type Ubr1 and HECT-type Ufd4 ubiquitin ligases (English)

1 reference

28 September 2017

3

Daniel Auerbach

1 reference

28 September 2017

Cheol-Sang Hwang

1

1 reference

28 September 2017

Anna Shemorry

series ordinal

2

1 reference

28 September 2017

Alexander Varshavsky

series ordinal

4

1 reference

28 September 2017

language of work or name

1 reference

14 November 2010

1 reference

28 September 2017

1 reference

28 September 2017

12

1 reference

28 September 2017

12

1 reference

28 September 2017

1177-1185

1 reference

describes a project that uses

28 September 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3003441/fullTextXML

inferred from PubMed Central ID database lookup

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Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases

28 September 2017

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28 September 2017

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28 September 2017

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Ubr1 and Ubr2 function in a quality control pathway for degradation of unfolded cytosolic proteins

28 September 2017

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28 September 2017

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28 September 2017

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Regulation of the polycomb protein Ring1B by self-ubiquitination or by E6-AP may have implications to the pathogenesis of Angelman syndrome

28 September 2017

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28 September 2017

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28 September 2017

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Ubiquitin chain elongation enzyme Ufd2 regulates a subset of Doa10 substrates

28 September 2017

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N-terminal acetylation of cellular proteins creates specific degradation signals

28 September 2017

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Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1

28 September 2017

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Ablation of arginylation in the mouse N-end rule pathway: loss of fat, higher metabolic rate, damaged spermatogenesis, and neurological perturbations

28 September 2017

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Glutamine-specific N-terminal amidase, a component of the N-end rule pathway

28 September 2017

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Molecular basis of substrate selection by the N-end rule adaptor protein ClpS

28 September 2017

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Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation

28 September 2017

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Origin and function of ubiquitin-like proteins

28 September 2017

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Two proteolytic pathways regulate DNA repair by cotargeting the Mgt1 alkylguanine transferase

28 September 2017

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Degradation of misfolded protein in the cytoplasm is mediated by the ubiquitin ligase Ubr1.

28 September 2017

1 reference

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Regulation of peptide import through phosphorylation of Ubr1, the ubiquitin ligase of the N-end rule pathway

28 September 2017

1 reference

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The HECT domain of TRIP12 ubiquitinates substrates of the ubiquitin fusion degradation pathway

28 September 2017

1 reference

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The substrate recognition domains of the N-end rule pathway

28 September 2017

1 reference

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The WW domain containing E3 ubiquitin protein ligase 1 upregulates ErbB2 and EGFR through RING finger protein 11.

28 September 2017

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Amino acids induce peptide uptake via accelerated degradation of CUP9, the transcriptional repressor of the PTR2 peptide transporter

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

Discovery of cellular regulation by protein degradation

28 September 2017

1 reference

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Diversity of degradation signals in the ubiquitin-proteasome system

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

The N-end rule pathway is a sensor of heme

28 September 2017

1 reference

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The mammalian N-end rule pathway: new insights into its components and physiological roles

28 September 2017

1 reference

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Structure and function of the yeast U-box-containing ubiquitin ligase Ufd2p

28 September 2017

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Yeast split-ubiquitin-based cytosolic screening system to detect interactions between transcriptionally active proteins

28 September 2017

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The N-end rule pathway for regulated proteolysis: prokaryotic and eukaryotic strategies

28 September 2017

1 reference

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Regulation of catalytic activities of HECT ubiquitin ligases

28 September 2017

1 reference

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Arginylation of beta-actin regulates actin cytoskeleton and cell motility

28 September 2017

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Lingering mysteries of ubiquitin-chain assembly

28 September 2017

1 reference

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Genomewide screen reveals a wide regulatory network for di/tripeptide utilization in Saccharomyces cerevisiae

28 September 2017

1 reference

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Multiubiquitylation by E4 enzymes: 'one size' doesn't fit all.

28 September 2017

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Degradation-mediated protein quality control in the nucleus

28 September 2017

1 reference

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An efficient system for high-level expression and easy purification of authentic recombinant proteins

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

Global analysis of protein expression in yeast

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

WW domain HECT E3s target Cbl RING finger E3s for proteasomal degradation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

Pairs of dipeptides synergistically activate the binding of substrate by ubiquitin ligase through dissociation of its autoinhibitory domain

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

Interaction between two ubiquitin-protein isopeptide ligases of different classes, CBLC and AIP4/ITCH.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

An essential role of N-terminal arginylation in cardiovascular development

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

Rapid and reliable protein extraction from yeast

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

Peptides accelerate their uptake by activating a ubiquitin-dependent proteolytic pathway

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

Physical association of ubiquitin ligases and the 26S proteasome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

The N-end rule: functions, mysteries, uses

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

Split ubiquitin as a sensor of protein interactions in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

A proteolytic pathway that recognizes ubiquitin as a degradation signal

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

In vivo half-life of a protein is a function of its amino-terminal residue

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

Ubiquitin as a degradation signal

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

ClpS is the recognition component for Escherichia coli substrates of the N-end rule degradation pathway.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

Substrate-binding sites of UBR1, the ubiquitin ligase of the N-end rule pathway

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

Detecting and measuring cotranslational protein degradation in vivo

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

The molecular principles of N-end rule recognition.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

Sequential E2s drive polyubiquitin chain assembly on APC targets

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

Autoregulation of an E2 enzyme by ubiquitin-chain assembly on its catalytic residue.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

The armadillo repeats of the Ufd4 ubiquitin ligase recognize ubiquitin-fusion proteins.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

Ubiquitin fusion technique and related methods

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

The N-end rule pathway as a nitric oxide sensor controlling the levels of multiple regulators

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

UFD4 lacking the proteasome-binding region catalyses ubiquitination but is impaired in proteolysis

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003441

Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae

19 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCB2121

Preparation of ubiquitinated substrates by the PY motif-insertion method for monitoring 26S proteasome activity

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21076411

12 December 2020

inferred from PubMed ID database lookup

Structural mechanisms underlying posttranslational modification by ubiquitin-like proteins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21076411

12 December 2020

inferred from PubMed ID database lookup

'Spalog' and 'sequelog': neutral terms for spatial and sequence similarity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21076411

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NCB2121

1 reference

28 September 2017

1 reference

28 September 2017

PubMed publication ID

21076411

1 reference