(Q41216084)

28 September 2017

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title

The roles of telomeres and telomerase in cell life span (English)

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28 September 2017

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Counter CM

1

1 reference

PubMed ID

8921986

28 September 2017

language of work or name

English

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publication date

1 October 1996

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28 September 2017

1 reference

28 September 2017

366

1 reference

28 September 2017

1

1 reference

28 September 2017

45-63

1 reference

An overhanging 3' terminus is a conserved feature of telomeres

28 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

The terminal organization of macronuclear DNA in Oxytricha fallax

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Saccharomyces telomeres acquire single-strand TG1-3 tails late in S phase

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Site-specific phasing in the chromatin of the rDNA in Dictyostelium discoideum

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Chromatin structure of the molecular ends of Oxytricha macronuclear DNA: phased nucleosomes and a telomeric complex

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Structure of the extrachromosomal ribosomal RNA chromatin of Physarum polycephalum

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Saccharomyces telomeres assume a non-nucleosomal chromatin structure

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Unusual chromatin in human telomeres

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Genetics and molecular biology of telomeres

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

The molecular structure of centromeres and telomeres

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Structure and function of telomeres

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Yeast telomere repeat sequence (TRS) improves circular plasmid segregation, and TRS plasmid segregation involves the RAP1 gene product

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Telomere-led premeiotic chromosome movement in fission yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Sandwiching of a gene within 12 kb of a functional telomere and alpha satellite does not result in silencing

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

A newly formed telomere in Ascaris suum does not exert a telomere position effect on a nearby gene

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

A developmentally regulated position effect at a telomeric locus in Trypanosoma brucei.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Position-effect variegation and the new biology of heterochromatin

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

A ribosomal DNA promoter replacing the promoter of a telomeric VSG gene expression site can be efficiently switched on and off in T. brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Origin of Concatemeric T7DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Telomerase and DNA end replication: no longer a lagging strand problem?

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Addition of telomere-associated HeT DNA sequences "heals" broken chromosome ends in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

An alternative pathway for yeast telomere maintenance rescues est1- senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Telomere elongation in immortal human cells without detectable telomerase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Alterations in p53 and p16INK4 expression and telomere length during spontaneous immortalization of Li-Fraumeni syndrome fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Purification of Tetrahymena telomerase and cloning of genes encoding the two protein components of the enzyme.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Functional reconstitution of wild-type and mutant Tetrahymena telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Developmentally programmed healing of chromosomes by telomerase in Tetrahymena

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Tetrahymena telomerase catalyzes nucleolytic cleavage and nonprocessive elongation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Telomerase activity in germline and embryonic cells of Xenopus.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

1 reference

7 January 2021

An in vitro assay for saccharomyces telomerase requires EST1

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Telomere terminal transferase activity in the hypotrichous ciliate Oxytricha nova and a model for replication of the ends of linear DNA molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Functional Evidence for an RNA Template in Telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Telomerase RNAs of different ciliates have a common secondary structure and a permuted template

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Oligonucleotides complementary to the Oxytricha nova telomerase RNA delineate the template domain and uncover a novel mode of primer utilization

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

TLC1: template RNA component of Saccharomyces cerevisiae telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Runaway telomere elongation caused by telomerase RNA gene mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Functional characterization and developmental regulation of mouse telomerase RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

The RNA component of human telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

The serial cultivation of human diploid cell strains

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Replicative senescence: the human fibroblast comes of age.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Senescence as a mode of tumor suppression

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Cellular senescence revisited: a review

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Doubling potential, calendar time, and senescence of human diploid cells in culture

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Cultured human fibroblasts: distribution of cell generations and a critical limit

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

The cell biology of human aging / Leonard Hayflick. - (1976)

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

HTLV-1 Tax: regulation of gene expression and disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Spontaneous in vitro immortalization of breast epithelial cells from a patient with Li-Fraumeni syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

NON-RANDOM CHROMOSOMAL ABERRATIONS IN SV 40-TRANSFORMED HUMAN CELLS.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

The sequence of chromosome aberrations during SV 40 transformation of a human diploid cell strain.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Human cell transformation by simian virus 40—A review

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Expression of SV40 large T antigen, but not small t antigen, is required for the induction of chromosomal aberrations in transformed human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

EARLY CHROMOSOMAL CHANGES IN SV40-INFECTED HUMAN FIBROBLAST CULTURES

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Quantitation of the frequency of immortalization of normal human diploid fibroblasts by SV40 large T-antigen

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

SV40-transformed human cells in crisis exhibit changes that occur in normal cellular senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

The frequency of immortalization of human fibroblasts and mammary epithelial cells transfected with SV40 large T-antigen

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Reversible cellular senescence: implications for immortalization of normal human diploid fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Mutation selection and the natural history of cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

A genetic model for colorectal tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

The clonal evolution of tumor cell populations

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Molecular cloning of human telomeres in yeast.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Cloning of human telomeres by complementation in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Hypervariable ultra-long telomeres in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Extensive telomere repeat arrays in mouse are hypervariable

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Human telomeres contain at least three types of G-rich repeat distributed non-randomly

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Structure and polymorphism of human telomere-associated DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Telomeres shorten during ageing of human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Telomeric repeat from T. thermophila cross hybridizes with human telomeres

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

The structure of a subterminal repeated sequence present on many human chromosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Telomere reduction in human colorectal carcinoma and with ageing

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Telomere shortening is associated with cell division in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Evidence for a critical telomere length in senescent human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Telomere shortening in chronic liver diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

In vivo loss of telomeric repeats with age in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Telomere positional effects and the regulation of cellular senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Telomere loss: mitotic clock or genetic time bomb?

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Telomere end-replication problem and cell aging

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Correlation between senescence and DNA repair in cells from young and old individuals and in premature aging syndromes.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Telomerase activation by the E6 gene product of human papillomavirus type 16.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Restoration of telomeres in human papillomavirus-immortalized human anogenital epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Restoration of the cellular senescence program and repression of telomerase by human chromosome 3.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Absence of p53 allows direct immortalization of hematopoietic cells by the myc and raf oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Robertsonian metacentrics of the house mouse lose telomeric sequences but retain some minor satellite DNA in the pericentromeric area

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Telomere change and loss of heterozygosity of mouse primary tumors and cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Distribution of non-telomeric sites of the (TTAGGG)n telomeric sequence in vertebrate chromosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Life span of individual yeast cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Daughter cells of Saccharomyces cerevisiae from old mothers display a reduced life span

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Calendar life span versus budding life span of Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Preparation and partial characterization of old yeast cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Telomere length constancy during aging of Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Mutation in the silencing gene S/R4 can delay aging in S. cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

A mutant with a defect in telomere elongation leads to senescence in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

The yeast KEM1 gene encodes a nuclease specific for G4 tetraplex DNA: implication of in vivo functions for this novel DNA structure

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Inhibition of telomerase by G-quartet DNA structures

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

RNA-dependent polymerase motifs in EST1: tentative identification of a protein component of an essential yeast telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Loss of a yeast telomere: arrest, recovery, and chromosome loss.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

An essential gene, ESR1, is required for mitotic cell growth, DNA repair and meiotic recombination in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

DNA Repair and Longevity Assurance in Paramecium tetraurelia

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Accumulation of DNA damages in aging Paramecium tetraurelia

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

Dynamics of telomere length variation in tetrahymena thermophila

1 reference

https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990006-8

7 January 2021

10.1016/S0165-1110(96)90006-8

Identifiers

DOI

0 references

PubMed ID

8921986

1 reference

PubMed ID

8921986