(Q41264930)

28 September 2017

title

A human follicular lymphoma B cell line hypermutates its functional immunoglobulin genes in vitro (English)

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28 September 2017

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Wu H

1

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28 September 2017

Pelkonen E

series ordinal

2

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28 September 2017

Knuutila S

series ordinal

3

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28 September 2017

Kaartinen M

series ordinal

4

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28 September 2017

language of work or name

English

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publication date

1 December 1995

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European Journal of Immunology

28 September 2017

published in

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28 September 2017

volume

25

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28 September 2017

issue

12

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28 September 2017

page(s)

3263-3269

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Distribution of mutations around rearranged heavy-chain antibody variable-region genes

28 September 2017

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mRNA sequences define an unusually restricted IgG response to 2-phenyloxazolone and its early diversification

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Somatic mutation and the maturation of immune response to 2-phenyl oxazolone

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Development of the primary antibody repertoire

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The role of somatic hypermutation in the generation of antibody diversity

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Antibody diversity: somatic hypermutation of rearranged VH genes

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Somatic generation of antibody diversity

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Stepwise intraclonal maturation of antibody affinity through somatic hypermutation

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Somatic mutations in antibodies expressed by germinal centre B cells early after primary immunization

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Maturation of the immune response in germinal centers

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Analysis of somatic mutation in five B cell subsets of human tonsil

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Clusters of point mutations are found exclusively around rearranged antibody variable genes

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7 January 2021

Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene

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7 January 2021

Somatic hypermutation in 5' flanking regions of heavy chain antibody variable regions

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7 January 2021

The 5' boundary of somatic hypermutation in a V kappa gene is in the leader intron

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Histologic transformation of follicular lymphoma to diffuse lymphoma represents tumor progression by a single malignant B cell

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7 January 2021

Clustering of extensive somatic mutations in the variable region of an immunoglobulin heavy chain gene from a human B cell lymphoma

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Somatic mutation in human B-cell tumors

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Clonal expansion in follicular lymphoma occurs subsequent to antigenic selection

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Somatic hypermutations in the immunoglobulin genes of two new human lymphoma lines of lymphatic follicle origin

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7 January 2021

The Somatic Hypermutation Activity of a Follicular Lymphoma Links to Large Insertions and Deletions of Immunoglobulin Genes

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7 January 2021

Cross-linking of surface IgG induces apoptosis in a bcl-2 expressing human follicular lymphoma line of mature B cell phenotype

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The percentages of six immunoglobulin isotypes in human antibodies to tetanus toxoid: standardization of isotype-specific second antibodies in solid-phase assay

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7 January 2021

Relative Immunogenicity in Mice of Different Regions of the Human IgG

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A rapid non-enzymatic method for the preparation of HMW DNA from blood for RFLP studies

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7 January 2021

Polymerase chain reaction reveals cloning artefacts

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7 January 2021

Recombination between an expressed immunoglobulin heavy-chain gene and a germline variable gene segment in a Ly 1+ B-cell lymphoma

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7 January 2021

Functional immunoglobulin light chain genes are replaced by ongoing rearrangements of germline V kappa genes to downstream J kappa segment in a murine B cell line

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7 January 2021

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7 January 2021

Prevention of programmed cell death in Burkitt lymphoma cell lines by bcl-2-dependent and -independent mechanisms

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7 January 2021

Mutations of the chloramphenicol acetyl transferase transgene driven by the immunoglobulin promoter and intron enhancer

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7 January 2021

Identifiers

DOI

10.1002/EJI.1830251210

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28 September 2017

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