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Plasmid accumulation reduces life span in Saccharomyces cerevisiae.
scientific article published on 6 August 2003
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PMCID
3668691
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12904293%20AND%20SRC:MED&resulttype=core&format=json
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6 November 2019
title
Plasmid accumulation reduces life span in Saccharomyces cerevisiae
(English)
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Europe PubMed Central
PMCID
3668691
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12904293%20AND%20SRC:MED&resulttype=core&format=json
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6 November 2019
main subject
Saccharomyces cerevisiae
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lifetime
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inferred from title
author
John P. Aris
series ordinal
2
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Europe PubMed Central
PMCID
3668691
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12904293%20AND%20SRC:MED&resulttype=core&format=json
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6 November 2019
author name string
Alaric A Falcón
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1
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Europe PubMed Central
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3668691
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12904293%20AND%20SRC:MED&resulttype=core&format=json
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6 November 2019
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English
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publication date
6 August 2003
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Europe PubMed Central
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3668691
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6 November 2019
published in
Journal of Biological Chemistry
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PMCID
3668691
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6 November 2019
volume
278
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Europe PubMed Central
PMCID
3668691
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12904293%20AND%20SRC:MED&resulttype=core&format=json
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6 November 2019
page(s)
41607-41617
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Europe PubMed Central
PMCID
3668691
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12904293%20AND%20SRC:MED&resulttype=core&format=json
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6 November 2019
issue
43
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Europe PubMed Central
PMCID
3668691
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12904293%20AND%20SRC:MED&resulttype=core&format=json
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6 November 2019
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based on heuristic
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cites work
Life span of individual yeast cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
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1 October 2017
Asymmetric inheritance of oxidatively damaged proteins during cytokinesis
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1 October 2017
Sir2p suppresses recombination of replication forks stalled at the replication fork barrier of ribosomal DNA in Saccharomyces cerevisiae.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
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1 October 2017
Mitochondrial DNA repair and aging
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1 October 2017
A novel mitochondrial protein, Tar1p, is encoded on the antisense strand of the nuclear 25S rDNA.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
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1 October 2017
High osmolarity extends life span in Saccharomyces cerevisiae by a mechanism related to calorie restriction
1 reference
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PubMed Central
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1 October 2017
Growing old: metabolic control and yeast aging
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1 October 2017
Separation of mother and daughter cells
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
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1 October 2017
Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
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1 October 2017
Getting started with yeast
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
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1 October 2017
Paradigms and pitfalls of yeast longevity research
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
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1 October 2017
Mutations in DNA replication genes reduce yeast life span
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
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1 October 2017
Model organisms as a guide to mammalian aging
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
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1 October 2017
hpr1Delta affects ribosomal DNA recombination and cell life span in Saccharomyces cerevisiae.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
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1 October 2017
Oxidative stress and signal transduction in Saccharomyces cerevisiae: insights into ageing, apoptosis and diseases.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
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1 October 2017
The short life span of Saccharomyces cerevisiae sgs1 and srs2 mutants is a composite of normal aging processes and mitotic arrest due to defective recombination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
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1 October 2017
Where it all starts: eukaryotic origins of DNA replication
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
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1 October 2017
Metabolic control and ageing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
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1 October 2017
Metabolic control and gene dysregulation in yeast aging
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
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1 October 2017
Ribosomal DNA replication fork barrier and HOT1 recombination hot spot: shared sequences but independent activities
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
retrieved
1 October 2017
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
retrieved
1 October 2017
Modulation of life-span by histone deacetylase genes in Saccharomyces cerevisiae.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
retrieved
1 October 2017
The inefficient replication origin from yeast ribosomal DNA is naturally impaired in the ARS consensus sequence and in DNA unwinding.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
retrieved
1 October 2017
Elimination of replication block protein Fob1 extends the life span of yeast mother cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
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1 October 2017
Interorganelle signaling is a determinant of longevity in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
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1 October 2017
Effects of mutations in DNA repair genes on formation of ribosomal DNA circles and life span in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
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1 October 2017
Mutational analysis of the structure and localization of the nucleolus in the yeast Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
retrieved
1 October 2017
Distribution of a limited Sir2 protein pool regulates the strength of yeast rDNA silencing and is modulated by Sir4p
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
retrieved
1 October 2017
Nop5p is a small nucleolar ribonucleoprotein component required for pre-18 S rRNA processing in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
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1 October 2017
Extrachromosomal rDNA circles--a cause of aging in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
retrieved
1 October 2017
Localization of Sir2p: the nucleolus as a compartment for silent information regulators
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
retrieved
1 October 2017
Redistribution of silencing proteins from telomeres to the nucleolus is associated with extension of life span in S. cerevisiae.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
retrieved
1 October 2017
A yeast gene product, Fob1 protein, required for both replication fork blocking and recombinational hotspot activities
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
retrieved
1 October 2017
Daughter cells of Saccharomyces cerevisiae from old mothers display a reduced life span
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
retrieved
1 October 2017
A polymerase switch in the synthesis of rRNA in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
retrieved
1 October 2017
Construction, Replication, and Chromatin Structure of TRP1 RI Circle, a Multiple-Copy Synthetic Plasmid Derived from Saccharomyces cerevisiae Chromosomal DNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
retrieved
1 October 2017
A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
retrieved
1 October 2017
Evidence for the involvement of a cytoplasmic factor in the aging of the yeast Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
retrieved
1 October 2017
Propagation and expression of cloned genes in yeast: 2-microns circle-based vectors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
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1 October 2017
Centromere structure and function in budding and fission yeasts
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
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1 October 2017
Multifunctional yeast high-copy-number shuttle vectors
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
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1 October 2017
The arrest of replication forks in the rDNA of yeast occurs independently of transcription
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
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1 October 2017
Direct evidence for SIR2 modulation of chromatin structure in yeast rDNA.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
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17 June 2018
Mutation in the silencing gene S/R4 can delay aging in S. cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
retrieved
17 June 2018
Maintenance of the 2 micron circle plasmid of Saccharomyces cerevisiae by sexual transmission: an example of a selfish DNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
retrieved
17 June 2018
A replication fork barrier at the 3' end of yeast ribosomal RNA genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
retrieved
17 June 2018
Pedigree analysis of plasmid segregation in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668691
retrieved
19 August 2018
AGING INSACCHAROMYCES CEREVISIAE
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M307025200
retrieved
21 January 2018
Clonal lethality caused by the yeast plasmid 2 mu DNA
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12904293
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Staining of bud scars and other cell wall chitin with calcofluor
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12904293
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1074/JBC.M307025200
1 reference
stated in
Europe PubMed Central
PMCID
3668691
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12904293%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
PMCID
3668691
1 reference
stated in
Europe PubMed Central
PMCID
3668691
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12904293%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
PubMed ID
12904293
1 reference
stated in
Europe PubMed Central
PMCID
3668691
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12904293%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
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