(Q41310580)

English

Phosphatidylinositol 4-kinase III beta is the target of oxoglaucine and pachypodol (Ro 09-0179) for their anti-poliovirus activities, and is located at upstream of the target step of brefeldin A.

scientific article published on June 2015

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25891300%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Phosphatidylinositol 4-kinase III beta is the target of oxoglaucine and pachypodol (Ro 09-0179) for their anti-poliovirus activities, and is located at upstream of the target step of brefeldin A (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25891300%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

object named as

poliovirus

1 reference

based on heuristic

inferred from title

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25891300%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

author name string

Stefan Philipov

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25891300%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Angel S Galabov

3

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Europe PubMed Central

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6 March 2020

publication date

1 June 2015

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25891300%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Microbiology and Immunology

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6 March 2020

59

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6 March 2020

6

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6 March 2020

338-347

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PubMed publication ID

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6 March 2020

Mechanism of action at the molecular level of the antiviral drug 3(2H)-isoflavene against type 2 poliovirus

1 reference

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Fisetin and rutin as 3C protease inhibitors of enterovirus A71.

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Inhibition of Enterovirus 71 replication by 7-hydroxyflavone and diisopropyl-flavon7-yl Phosphate

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21 January 2018

Anti-enterovirus 71 effects of chrysin and its phosphate ester

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21 January 2018

Antiviral activity of natural occurring flavonoids in vitro

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21 January 2018

4'-Hydroxy-3-methoxyflavones with potent antipicornavirus activity.

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Inhibition of enterovirus 71 replication by chrysosplenetin and penduletin

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21 January 2018

Antipicornavirus flavone Ro 09-0179

1 reference

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21 January 2018

Viral reorganization of the secretory pathway generates distinct organelles for RNA replication

1 reference

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21 January 2018

Phosphatidylinositol-4 kinase III beta and oxysterol-binding protein accumulate unesterified cholesterol on poliovirus-induced membrane structure.

1 reference

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21 January 2018

Rhinovirus uses a phosphatidylinositol 4-phosphate/cholesterol counter-current for the formation of replication compartments at the ER-Golgi interface.

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21 January 2018

Itraconazole inhibits enterovirus replication by targeting the oxysterol-binding protein

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21 January 2018

A cytoplasmic 57-kDa protein that is required for translation of picornavirus RNA by internal ribosomal entry is identical to the nuclear pyrimidine tract-binding protein

1 reference

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21 January 2018

A viral protein that blocks Arf1-mediated COP-I assembly by inhibiting the guanine nucleotide exchange factor GBF1.

1 reference

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21 January 2018

A nucleo-cytoplasmic SR protein functions in viral IRES-mediated translation initiation

1 reference

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21 January 2018

Valosin-containing protein (VCP/p97) is required for poliovirus replication and is involved in cellular protein secretion pathway in poliovirus infection

1 reference

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21 January 2018

Picornavirus modification of a host mRNA decay protein

1 reference

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21 January 2018

ACBD3-mediated recruitment of PI4KB to picornavirus RNA replication sites

1 reference

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21 January 2018

An RNA virus hijacks an incognito function of a DNA repair enzyme

1 reference

https://api.crossref.org/works/10.1111%2F1348-0421.12261

21 January 2018

Oxysterol-binding protein family I is the target of minor enviroxime-like compounds.

1 reference

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21 January 2018

Increased long chain acyl-Coa synthetase activity and fatty acid import is linked to membrane synthesis for development of picornavirus replication organelles

1 reference

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21 January 2018

Synthesis of syn and anti isomers of 6-[[(hydroxyimino)phenyl]methyl]-1-[(1-methylethyl)sulfonyl]-1H-benzimidazol-2-amine. Inhibitors of rhinovirus multiplication

1 reference

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21 January 2018

Characterization of pharmacologically active compounds that inhibit poliovirus and enterovirus 71 infectivity

1 reference

https://api.crossref.org/works/10.1111%2F1348-0421.12261

21 January 2018

A bifunctional anti-enterovirus compound that inhibits replication and the early stage of enterovirus 71 infection.

1 reference

https://api.crossref.org/works/10.1111%2F1348-0421.12261

21 January 2018

Phosphatidylinositol 4-kinase III beta is a target of enviroxime-like compounds for antipoliovirus activity.

1 reference

https://api.crossref.org/works/10.1111%2F1348-0421.12261

21 January 2018

The role of phosphatidylinositol 4-kinases and phosphatidylinositol 4-phosphate during viral replication

1 reference

https://api.crossref.org/works/10.1111%2F1348-0421.12261

21 January 2018

Cellular kinase inhibitors that suppress enterovirus replication have a conserved target in viral protein 3A similar to that of enviroxime.

1 reference

https://api.crossref.org/works/10.1111%2F1348-0421.12261

21 January 2018

Quantitative analysis of poliomyelitis-like paralysis in mice induced by a poliovirus replicon.

1 reference

https://api.crossref.org/works/10.1111%2F1348-0421.12261

21 January 2018

The poliovirus replication machinery can escape inhibition by an antiviral drug that targets a host cell protein

1 reference

https://api.crossref.org/works/10.1111%2F1348-0421.12261

21 January 2018

A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling

1 reference

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21 January 2018

Spectrum and characteristics of the virus inhibitory action of 2-(alpha-hydroxybenzyl)-benzimidazole

1 reference

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21 January 2018

Treatment with oxoglaucine can enhance host resistance to Candida albicans infection of mice with adjuvant arthritis

1 reference

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21 January 2018

Toll-like receptor-mediated anti-inflammatory action of glaucine and oxoglaucine.

1 reference

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21 January 2018

Antiplasmodial activity of aporphine alkaloids and sesquiterpene lactones from Liriodendron tulipifera L

1 reference

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21 January 2018

Anti-hepatitis C virus activity and toxicity of type III phosphatidylinositol-4-kinase beta inhibitors

1 reference

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21 January 2018

Targeting Plasmodium PI(4)K to eliminate malaria

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21 January 2018

Complex dynamic development of poliovirus membranous replication complexes

1 reference

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21 January 2018

Generation of unique poliovirus RNA replication organelles

1 reference

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21 January 2018

Cellular COPII proteins are involved in production of the vesicles that form the poliovirus replication complex.

1 reference

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21 January 2018

Poliovirus replication requires the N-terminus but not the catalytic Sec7 domain of ArfGEF GBF1.

1 reference

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21 January 2018

Experimentally guided models reveal replication principles that shape the mutation distribution of RNA viruses

1 reference

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21 January 2018

Involvement of membrane traffic in the replication of poliovirus genomes: effects of brefeldin A

1 reference

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21 January 2018

A novel, broad-spectrum inhibitor of enterovirus replication that targets host cell factor phosphatidylinositol 4-kinase IIIβ.

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21 January 2018

Avoiding drug-resistance development by novel approach of combining anti-enteroviral substances against coxsackievirus B1 infection in mice

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Prevention of rhinovirus and poliovirus uncoating by WIN 51711, a new antiviral drug

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21 January 2018

Phosphatidylinositol 4-kinase III beta is essential for replication of human rhinovirus and its inhibition causes a lethal phenotype in vivo

1 reference

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21 January 2018

Identifiers

10.1111/1348-0421.12261

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25891300%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25891300%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

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