(Q41447335)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25673868%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

The JAK/STAT3 pathway is a common inducer of astrocyte reactivity in Alzheimer's and Huntington's diseases (English)

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29 February 2020

0 references

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1

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29 February 2020

Kelly Ceyzériat

2

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Maria Angeles Carrillo-de Sauvage

29 February 2020

3

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29 February 2020

Romina Aron Badin

12

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29 February 2020

Marc Dhenain

13

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29 February 2020

Nicole Déglon

14

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29 February 2020

Emmanuel Brouillet

16

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29 February 2020

Gilles Bonvento

17

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29 February 2020

Carole Escartin

18

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29 February 2020

15

Philippe Hantraye

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29 February 2020

5

Gwennaëlle Auregan

1 reference

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29 February 2020

6

Martine Guillermier

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29 February 2020

9

Diane Houitte

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29 February 2020

10

Emilie Faivre

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29 February 2020

author name string

Fabien Aubry

4

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29 February 2020

Marta Ruiz

7

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29 February 2020

Fanny Petit

8

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29 February 2020

Matthias Vandesquille

11

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29 February 2020

language of work or name

English

0 references

publication date

1 February 2015

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29 February 2020

published in

Journal of Neuroscience

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29 February 2020

volume

35

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29 February 2020

issue

6

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29 February 2020

page(s)

2817-2829

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Activation of the JAK/STAT pathway following transient focal cerebral ischemia: signaling through Jak1 and Stat3 in astrocytes

29 February 2020

cites work

1 reference

12 December 2020

Complete and long-term rescue of lesioned adult motoneurons by lentiviral-mediated expression of glial cell line-derived neurotrophic factor in the facial nucleus.

1 reference

12 December 2020

A unified hypothesis on the lineage of neural stem cells.

1 reference

12 December 2020

Lentiviral-mediated delivery of mutant huntingtin in the striatum of rats induces a selective neuropathology modulated by polyglutamine repeat size, huntingtin expression levels, and protein length.

1 reference

12 December 2020

Signal transducers and activators of transcription 3 (STAT3) inhibits transcription of the inducible nitric oxide synthase gene by interacting with nuclear factor kappaB

1 reference

12 December 2020

Stats: transcriptional control and biological impact

1 reference

12 December 2020

Induction of STAT3 signaling in activated astrocytes and sprouting septal neurons following entorhinal cortex lesion in adult rats.

1 reference

12 December 2020

Mutant huntingtin causes context-dependent neurodegeneration in mice with Huntington's disease.

1 reference

12 December 2020

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

1 reference

12 December 2020

Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats

1 reference

12 December 2020

Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase

1 reference

12 December 2020

Induction of gp130-related Cytokines and Activation of JAK2/STAT3 Pathway in Astrocytes Precedes Up-regulation of Glial Fibrillary Acidic Protein in the 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Model of Neurodegeneration

1 reference

12 December 2020

Ciliary neurotrophic factor activates astrocytes, redistributes their glutamate transporters GLAST and GLT-1 to raft microdomains, and improves glutamate handling in vivo.

1 reference

12 December 2020

Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury.

1 reference

12 December 2020

Redefining the concept of reactive astrocytes as cells that remain within their unique domains upon reaction to injury

1 reference

12 December 2020

Expression of mutated huntingtin fragment in the putamen is sufficient to produce abnormal movement in non-human primates

1 reference

12 December 2020

Shared principles in NF-kappaB signaling

1 reference

12 December 2020

STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injury

1 reference

12 December 2020

Amyloid-beta causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons.

1 reference

12 December 2020

Targeted activation of astrocytes: a potential neuroprotective strategy.

1 reference

12 December 2020

Engineered lentiviral vector targeting astrocytes in vivo

1 reference

12 December 2020

Activation of signal transducer and activator of transcription-3 in the spinal cord of sporadic amyotrophic lateral sclerosis patients

1 reference

12 December 2020

Amyloid deposition and inflammation in APPswe/PS1dE9 mouse model of Alzheimer's disease

1 reference

12 December 2020

Activation of STAT3 and inhibitory effects of pioglitazone on STAT3 activity in a mouse model of SOD1-mutated amyotrophic lateral sclerosis

1 reference

12 December 2020

Astrocytes: biology and pathology

1 reference

12 December 2020

In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects

1 reference

12 December 2020

Reactive astrocytes as therapeutic targets for CNS disorders

1 reference

12 December 2020

Signaling pathways in reactive astrocytes, a genetic perspective

1 reference

12 December 2020

Astroglial inhibition of NF-κB does not ameliorate disease onset and progression in a mouse model for amyotrophic lateral sclerosis (ALS)

1 reference

12 December 2020

The role of IκB kinase complex in the neurobiology of Huntington's disease

1 reference

12 December 2020

Viral-mediated overexpression of mutant huntingtin to model HD in various species

1 reference

12 December 2020

Protein aggregates in Huntington's disease.

1 reference

12 December 2020

Genomic analysis of reactive astrogliosis

1 reference

12 December 2020

Attenuating astrocyte activation accelerates plaque pathogenesis in APP/PS1 mice

1 reference

12 December 2020

Astrocytes: conductors of the Alzheimer disease neuroinflammatory symphony

1 reference

12 December 2020

Targeting astrocytes ameliorates neurologic changes in a mouse model of Alzheimer's disease.

1 reference

12 December 2020

Attenuated inflammatory response in triggering receptor expressed on myeloid cells 2 (TREM2) knock-out mice following stroke

1 reference

12 December 2020

A critical role of astrocyte-mediated nuclear factor-κB-dependent inflammation in Huntington's disease

1 reference

12 December 2020

SOCS3 binds specific receptor–JAK complexes to control cytokine signaling by direct kinase inhibition

1 reference

12 December 2020

NF-κB and STAT3 signaling pathways collaboratively link inflammation to cancer

1 reference

12 December 2020

A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin

1 reference

12 December 2020

Soluble forms of polyQ-expanded huntingtin rather than large aggregates cause endoplasmic reticulum stress

1 reference

12 December 2020

Heterogeneity of reactive astrocytes

1 reference

12 December 2020

HTT-lowering reverses Huntington's disease immune dysfunction caused by NFκB pathway dysregulation

1 reference

12 December 2020

Reactive gliosis and the multicellular response to CNS damage and disease.

1 reference

12 December 2020

Trans-Signaling Is a Dominant Mechanism for the Pathogenic Actions of Interleukin-6 in the Brain

1 reference

12 December 2020

Microglia induce motor neuron death via the classical NF-κB pathway in amyotrophic lateral sclerosis

1 reference

12 December 2020

Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice

1 reference

12 December 2020

Astrocyte response to motor neuron injury promotes structural synaptic plasticity via STAT3-regulated TSP-1 expression

1 reference

12 December 2020

Transneuronal propagation of mutant huntingtin contributes to non-cell autonomous pathology in neurons

1 reference

12 December 2020

Early activation of STAT3 regulates reactive astrogliosis induced by diverse forms of neurotoxicity

1 reference

12 December 2020

Loss of the thyroid hormone-binding protein Crym renders striatal neurons more vulnerable to mutant huntingtin in Huntington's disease

1 reference

12 December 2020

Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease.

1 reference

12 December 2020

Neuropathological classification of Huntington's disease

1 reference

12 December 2020

Senile dementia of Alzheimer type: astroglial reaction to extracellular neurofibrillary tangles in the hippocampus. An immunocytochemical and electron-microscopic study.

1 reference

12 December 2020

Characterization of a pathway for ciliary neurotrophic factor signaling to the nucleus

1 reference

12 December 2020

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

1 reference

12 December 2020

A family of cytokine-inducible inhibitors of signalling

1 reference

12 December 2020

Identification of SOCS-3 as a potential mediator of central leptin resistance

1 reference

12 December 2020

Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin

1 reference

12 December 2020

10.1523/JNEUROSCI.3516-14.2015

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25673868%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

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29 February 2020

PubMed publication ID

25673868

1 reference