(Q41558826)

3 October 2017

Inhibition of protein translocation at the endoplasmic reticulum promotes activation of the unfolded protein response (English)

1 reference

3 October 2017

endoplasmic reticulum

0 references

author

Stephen High

11

1 reference

3 October 2017

14

Eileithyia Swanton

0 references

Anna C. Callan

7

Anna C Callan

0 references

Roger C. Whitehead

13

Roger C Whitehead

0 references

Sabine Flitsch

12

Sabine L Flitsch

0 references

Stig Linder

9

Stig Linder

1 reference

3 October 2017

Craig McKibbin

1

1 reference

3 October 2017

Alina Mares

2

1 reference

3 October 2017

Michela Piacenti

3

1 reference

3 October 2017

Helen Williams

4

1 reference

3 October 2017

Peristera Roboti

5

1 reference

3 October 2017

Marjo Puumalainen

6

1 reference

3 October 2017

Karolina Lesiak-Mieczkowska

8

1 reference

3 October 2017

Hanna Harant

10

1 reference

3 October 2017

language of work or name

English

0 references

publication date

1 March 2012

1 reference

3 October 2017

10

1 reference

based on heuristic

inferred from page(s)

published in

Biochemical Journal

1 reference

3 October 2017

442

1 reference

3 October 2017

3

1 reference

3 October 2017

639-648

1 reference

Creative Commons Attribution-NonCommercial 2.5 Generic

3 October 2017

start time

25 July 2019

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Inhibition of proteasome deubiquitinating activity as a new cancer therapy

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Eeyarestatin 1 interferes with both retrograde and anterograde intracellular trafficking pathways

6 June 2018

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Protein targeting and degradation are coupled for elimination of mislocalized proteins

6 June 2018

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Enzymatic blockade of the ubiquitin-proteasome pathway

6 June 2018

1 reference

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Cytosolic aggregates perturb the degradation of nontranslocated secretory and membrane proteins

6 June 2018

1 reference

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The ERAD inhibitor Eeyarestatin I is a bifunctional compound with a membrane-binding domain and a p97/VCP inhibitory group

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

Substrate specificity of the TIM22 mitochondrial import pathway revealed with small molecule inhibitor of protein translocation

6 June 2018

1 reference

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Flavonol Activation Defines an Unanticipated Ligand-Binding Site in the Kinase-RNase Domain of IRE1

6 June 2018

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Signal sequence insufficiency contributes to neurodegeneration caused by transmembrane prion protein

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

Eeyarestatin I inhibits Sec61-mediated protein translocation at the endoplasmic reticulum

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

Differences in endoplasmic-reticulum quality control determine the cellular response to disease-associated mutants of proteolipid protein

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

Functional depletion of mahogunin by cytosolically exposed prion protein contributes to neurodegeneration

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

A novel role for MAP1 LC3 in nonautophagic cytoplasmic vacuolation death of cancer cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

Apratoxin a reversibly inhibits the secretory pathway by preventing cotranslational translocation

6 June 2018

1 reference

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Delivering proteins for export from the cytosol

6 June 2018

1 reference

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ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells

6 June 2018

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Induction of the lysosomal apoptosis pathway by inhibitors of the ubiquitin-proteasome system

6 June 2018

1 reference

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Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

One step at a time: endoplasmic reticulum-associated degradation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1.

6 June 2018

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Retrotranslocation of prion proteins from the endoplasmic reticulum by preventing GPI signal transamidation

6 June 2018

1 reference

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SRP keeps polypeptides translocation-competent by slowing translation to match limiting ER-targeting sites

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

Segregation and rapid turnover of EDEM1 by an autophagy-like mechanism modulates standard ERAD and folding activities

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

Adapting proteostasis for disease intervention

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

Inhibition of p97-dependent protein degradation by Eeyarestatin I

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

Endoplasmic reticulum stress in disease pathogenesis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

Integrated endoplasmic reticulum stress responses in cancer

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

Photo-leucine incorporation reveals the target of a cyclodepsipeptide inhibitor of cotranslational translocation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

Signal integration in the endoplasmic reticulum unfolded protein response

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

Human endoplasmic reticulum mannosidase I is subject to regulated proteolysis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

Conditions of endoplasmic reticulum stress favor the accumulation of cytosolic prion protein

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

Selective inhibition of cotranslational translocation of vascular cell adhesion molecule 1

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

Dissection of the dislocation pathway for type I membrane proteins with a new small molecule inhibitor, eeyarestatin

6 June 2018

1 reference

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Distinct roles for the AAA ATPases NSF and p97 in the secretory pathway

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

Quality control in the endoplasmic reticulum

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

Dislocation and degradation from the ER are regulated by cytosolic stress

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

Aggresomes: a cellular response to misfolded proteins

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

Isolation of intracellular membranes by means of sodium carbonate treatment: application to endoplasmic reticulum

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

Up‐regulation of endoplasmic reticulum stress‐related genes during the early phase of treatment of cultured cortical neurons by the proteasomal inhibitor lactacystin

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

A functional genomics approach to the mode of action of apratoxin A.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

Toxicity of tunicamycin to cultured brain neurons: ultrastructure of the degenerating neurons

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3286858

19 August 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111220

The alpha chain of the T cell antigen receptor is degraded in the cytosol

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22145777

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inhibition of vascular endothelial growth factor cotranslational translocation by the cyclopeptolide CAM741

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22145777

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1042/BJ20111220

1 reference

3 October 2017

1 reference

3 October 2017

PubMed publication ID

22145777

1 reference