(Q41568940)

3 October 2017

Mammalian frataxin directly enhances sulfur transfer of NFS1 persulfide to both ISCU and free thiols (English)

1 reference

3 October 2017

6

1 reference

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31 May 2020

Laura Belot

4

1 reference

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31 May 2020

Benoît D'Autréaux

8

1 reference

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31 May 2020

author name string

Aubérie Parent

1

1 reference

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31 May 2020

Xavier Elduque

2

1 reference

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31 May 2020

David Cornu

3

1 reference

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31 May 2020

Jean-Pierre Le Caer

5

1 reference

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31 May 2020

Michel B Toledano

7

1 reference

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31 May 2020

language of work or name

English

0 references

publication date

19 January 2015

1 reference

3 October 2017

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25597503%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

volume

6

1 reference

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31 May 2020

page(s)

5686

1 reference

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https://scigraph.springernature.com/pub.10.1038/ncomms6686

31 May 2020

exact match

0 references

cites work

Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion

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7 January 2021

The yeast frataxin homolog Yfh1p plays a specific role in the maturation of cellular Fe/S proteins

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7 January 2021

Mouse models for Friedreich ataxia exhibit cardiomyopathy, sensory nerve defect and Fe-S enzyme deficiency followed by intramitochondrial iron deposits

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7 January 2021

Iron-dependent self-assembly of recombinant yeast frataxin: implications for Friedreich ataxia

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7 January 2021

Iron-sulfur cluster biosynthesis: characterization of Escherichia coli CYaY as an iron donor for the assembly of [2Fe-2S] clusters in the scaffold IscU.

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7 January 2021

Mitochondrial iron detoxification is a primary function of frataxin that limits oxidative damage and preserves cell longevity

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7 January 2021

Iron-induced oligomerization of yeast frataxin homologue Yfh1 is dispensable in vivo

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7 January 2021

Frataxin: a protein in search for a function

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7 January 2021

Evidence that yeast frataxin is not an iron storage protein in vivo

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7 January 2021

Friedreich ataxia: the oxidative stress paradox

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7 January 2021

Mammalian frataxin controls sulfur production and iron entry during de novo Fe4S4 cluster assembly

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7 January 2021

Frataxin directly stimulates mitochondrial cysteine desulfurase by exposing substrate-binding sites, and a mutant Fe-S cluster scaffold protein with frataxin-bypassing ability acts similarly

1 reference

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7 January 2021

Iron-sulfur protein maturation in human cells: evidence for a function of frataxin

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7 January 2021

Human frataxin is an allosteric switch that activates the Fe-S cluster biosynthetic complex

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7 January 2021

Iron-sulfur cluster biosynthesis in bacteria: Mechanisms of cluster assembly and transfer

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7 January 2021

Function and biogenesis of iron-sulphur proteins

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7 January 2021

Role of human mitochondrial Nfs1 in cytosolic iron-sulfur protein biogenesis and iron regulation

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7 January 2021

RNA silencing of mitochondrial m-Nfs1 reduces Fe-S enzyme activity both in mitochondria and cytosol of mammalian cells

1 reference

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7 January 2021

The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins

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7 January 2021

Human mitochondrial chaperone (mtHSP70) and cysteine desulfurase (NFS1) bind preferentially to the disordered conformation, whereas co-chaperone (HSC20) binds to the structured conformation of the iron-sulfur cluster scaffold protein (ISCU).

1 reference

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7 January 2021

An interaction between frataxin and Isu1/Nfs1 that is crucial for Fe/S cluster synthesis on Isu1.

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7 January 2021

Components involved in assembly and dislocation of iron-sulfur clusters on the scaffold protein Isu1p

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7 January 2021

Mammalian frataxin: an essential function for cellular viability through an interaction with a preformed ISCU/NFS1/ISD11 iron-sulfur assembly complex.

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7 January 2021

Structure, function, and formation of biological iron-sulfur clusters

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7 January 2021

Building Fe-S proteins: bacterial strategies.

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7 January 2021

The Nfs1 interacting protein Isd11 has an essential role in Fe/S cluster biogenesis in mitochondria

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7 January 2021

Human ISD11 is essential for both iron-sulfur cluster assembly and maintenance of normal cellular iron homeostasis

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7 January 2021

Sulfur transfer from IscS to IscU: the first step in iron-sulfur cluster biosynthesis.

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7 January 2021

Role of conserved cysteines in mediating sulfur transfer from IscS to IscU

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7 January 2021

Transfer of sulfur from IscS to IscU during Fe/S cluster assembly

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7 January 2021

Human frataxin activates Fe-S cluster biosynthesis by facilitating sulfur transfer chemistry

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7 January 2021

Effector role reversal during evolution: the case of frataxin in Fe-S cluster biosynthesis

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7 January 2021

Bacterial frataxin CyaY is the gatekeeper of iron-sulfur cluster formation catalyzed by IscS

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7 January 2021

The role of CyaY in iron sulfur cluster assembly on the E. coli IscU scaffold protein

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7 January 2021

Spontaneous α-N-6-Phosphogluconoylation of a “His Tag” inEscherichia coli:The Cause of Extra Mass of 258 or 178 Da in Fusion Proteins

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7 January 2021

Persulfide reactivity in the detection of protein s-sulfhydration.

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7 January 2021

Formation and properties of [4Fe-4S] clusters on the IscU scaffold protein

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7 January 2021

[2Fe-2S]-ferredoxin binds directly to cysteine desulfurase and supplies an electron for iron-sulfur cluster assembly but is displaced by the scaffold protein or bacterial frataxin

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7 January 2021

Humans possess two mitochondrial ferredoxins, Fdx1 and Fdx2, with distinct roles in steroidogenesis, heme, and Fe/S cluster biosynthesis

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7 January 2021

Glutathione revisited: a vital function in iron metabolism and ancillary role in thiol-redox control.

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7 January 2021

Maturation of cytosolic iron-sulfur proteins requires glutathione

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7 January 2021

Mechanism of cysteine desulfurase Slr0387 from Synechocystis sp. PCC 6803: kinetic analysis of cleavage of the persulfide intermediate by chemical reductants

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7 January 2021

Kinetic and mutational studies of three NifS homologs from Escherichia coli: mechanistic difference between L-cysteine desulfurase and L-selenocysteine lyase reactions

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7 January 2021

Normal and Friedreich ataxia cells express different isoforms of frataxin with complementary roles in iron-sulfur cluster assembly

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7 January 2021

Identification of a Nfs1p-bound persulfide intermediate in Fe-S cluster synthesis by intact mitochondria

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7 January 2021

Hydrogen sulfide-linked sulfhydration of NF-κB mediates its antiapoptotic actions

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7 January 2021

Detection of protein S-sulfhydration by a tag-switch technique.

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7 January 2021

Studies on the synthesis of the Fe-S cluster of dihydroxy-acid dehydratase in escherichia coli crude extract. Isolation of O-acetylserine sulfhydrylases A and B and beta-cystathionase based on their ability to mobilize sulfur from cysteine and to pa

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7 January 2021

The mitochondrial pool of free amino acids reflects the composition of mitochondrial DNA-encoded proteins: indication of a post- translational quality control for protein synthesis

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7 January 2021

Identifiers

DOI

10.1038/NCOMMS6686

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25597503%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

31 May 2020

ADS bibcode

2015NatCo...6.5686P

0 references

0 references

1 reference

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