(Q41578013)

4 October 2017

Second generation tetrahydroquinoline-based protein farnesyltransferase inhibitors as antimalarials (English)

1 reference

4 October 2017

0 references

18

Michael H Gelb

1 reference

4 October 2017

14

Frederick S Buckner

1 reference

4 October 2017

5

Kasey Rivas

1 reference

4 October 2017

1

Pravin Bendale

1 reference

4 October 2017

6

Laxman Nallan

1 reference

4 October 2017

9

Sudha Ankala

1 reference

4 October 2017

16

Christophe L M J Verlinde

1 reference

4 October 2017

15

Debopam Chakrabarti

1 reference

4 October 2017

8

Kohei Yokoyama

1 reference

4 October 2017

12

Louis J Lombardo

1 reference

Praveen Kumar Suryadevara

4 October 2017

3

object named as

Praveen Kumar Suryadevara

1 reference

4 October 2017

17

Wesley C Van Voorhis

1 reference

4 October 2017

2

Srinivas Olepu

1 reference

4 October 2017

10

Prakash Rao Pendyala

1 reference

4 October 2017

Vivek Bulbule

4

1 reference

4 October 2017

Brian Smart

7

1 reference

4 October 2017

David Floyd

11

1 reference

4 October 2017

David K Williams

13

1 reference

4 October 2017

language of work or name

English

0 references

publication date

28 August 2007

1 reference

Journal of Medicinal Chemistry

4 October 2017

1 reference

4 October 2017

50

1 reference

4 October 2017

19

1 reference

4 October 2017

4585-4605

1 reference

Efficacy, Pharmacokinetics, and Metabolism of Tetrahydroquinoline Inhibitors of Plasmodium falciparum Protein Farnesyltransferase

4 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894570

Resistance mutations at the lipid substrate binding site of Plasmodium falciparum protein farnesyltransferase

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894570

Design, synthesis, and structure-activity relationships of tetrahydroquinoline-based farnesyltransferase inhibitors.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894570

Crystal structures of the anticancer clinical candidates R115777 (Tipifarnib) and BMS-214662 complexed with protein farnesyltransferase suggest a mechanism of FTI selectivity

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894570

Inhibitors of farnesyltransferase: a rational approach to cancer chemotherapy?

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894570

PlasmoDB: the Plasmodium genome resource. A database integrating experimental and computational data

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894570

Protein farnesyltransferase and protein prenylation in Plasmodium falciparum

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894570

Discovery of (R)-7-cyano-2,3,4, 5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3- (phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-benzodiazepine (BMS-214662), a farnesyltransferase inhibitor with potent preclinical antitumor activity

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894570

Protein prenyl transferase activities of Plasmodium falciparum

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894570

QXP: powerful, rapid computer algorithms for structure-based drug design.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894570

Differential prenyl pyrophosphate binding to mammalian protein geranylgeranyltransferase-I and protein farnesyltransferase and its consequence on the specificity of protein prenylation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894570

Comparative protein modelling by satisfaction of spatial restraints

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894570

Human malaria parasites in continuous culture

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894570

Protein farnesyltransferase inhibitors exhibit potent antimalarial activity

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894570

Resistance to a protein farnesyltransferase inhibitor in Plasmodium falciparum

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894570

Synthesis of chiral nonracemic 1-(2-pyridinyl)ethylamines: stereospecific introduction of amino function onto the 2-pyridinylmethyl carbon center

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894570

Estimation of the ionization pK(a) of pharmaceutical substances using the computer program Sparc

19 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17722901

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Attempted inhibition of histidine decarboxylase with beta-alkyl analogues of histidine

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17722901

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/JM0703340

1 reference

4 October 2017

1 reference

4 October 2017

PubMed publication ID

17722901

1 reference