(Q41615096)

5 October 2017

1 reference

title

Inhibition of Ras prenylation: a novel approach to cancer chemotherapy (English)

1 reference

5 October 2017

1 reference

Sebti SM

1

1 reference

PubMed ID

9336018

5 October 2017

Hamilton AD

series ordinal

2

1 reference

5 October 2017

1 January 1997

1 reference

Pharmacology & Therapeutics

5 October 2017

1 reference

5 October 2017

74

1 reference

5 October 2017

103-114

1 reference

5 October 2017

1

1 reference

cDNA cloning of component A of Rab geranylgeranyl transferase and demonstration of its role as a Rab escort protein

5 October 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

CAAX geranylgeranyl transferase transfers farnesyl as efficiently as geranylgeranyl to RhoB

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

1 reference

7 January 2021

Novel tricyclic inhibitors of farnesyl protein transferase. Biochemical characterization and inhibition of Ras modification in transfected Cos cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

Farnesyl transferase inhibitors: the successes and surprises of a new class of potential cancer chemotherapeutics

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

Different analogues of farnesyl pyrophosphate inhibit squalene synthase and protein:farnesyltransferase to different extents

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeutic

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

Pseudopeptide inhibitors of Ras farnesyl-protein transferase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

All ras proteins are polyisoprenylated but only some are palmitoylated

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

Potent, cell active, non-thiol tetrapeptide inhibitors of farnesyltransferase.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

Benzodiazepine peptidomimetics: potent inhibitors of Ras farnesylation in animal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

Polylysine and CVIM sequences of K-RasB dictate specificity of prenylation and confer resistance to benzodiazepine peptidomimetic in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

Development of inhibitors of protein farnesylation as potential chemotherapeutic agents.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

Farnesylamine: an inhibitor of farnesylation and growth of ras-transformed cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

Ras CAAX peptidomimetic FTI-277 selectively blocks oncogenic Ras signaling by inducing cytoplasmic accumulation of inactive Ras-Raf complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

Disruption of oncogenic K-Ras4B processing and signaling by a potent geranylgeranyltransferase I inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

Signal transduction. How receptors turn Ras on.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

CAAX peptidomimetic FTI-244 decreases platelet-derived growth factor receptor tyrosine phosphorylation levels and inhibits stimulation of phosphatidylinositol 3-kinase but not mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

Platelet-derived growth factor receptor tyrosine phosphorylation requires protein geranylgeranylation but not farnesylation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

Phosphinyl acid-based bisubstrate analog inhibitors of Ras farnesyl protein transferase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

Design and synthesis of non-peptide Ras CAAX mimetics as potent farnesyltransferase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

Protein farnesyltransferase and geranylgeranyltransferase share a common alpha subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

Inhibitors of Ras farnesyltransferases

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

A non-peptide mimetic of Ras-CAAX: selective inhibition of farnesyltransferase and Ras processing

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

Burkitt lymphoma Daudi cells contain two distinct farnesyltransferases with different divalent cation requirements

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

2-substituted piperazines as constrained amino acids. Application to the synthesis of potent, non carboxylic acid inhibitors of farnesyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

The p21 ras C-terminus is required for transformation and membrane association

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2900014-4

7 January 2021

10.1016/S0163-7258(97)00014-4

Identifiers

DOI

1 reference

5 October 2017

1 reference

PubMed ID

9336018