(Q41625143)

5 October 2017

title

Transposon mutagenesis identifies genes and evolutionary forces driving gastrointestinal tract tumor progression (English)

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5 October 2017

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6

Michael B Mann

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Alistair G Rust

4

object named as

Alistair G Rust

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Hideto Koso

object named as

Hideto Koso

3

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Neal G. Copeland

9

object named as

Neal G Copeland

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5 October 2017

10

Nancy A Jenkins

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5 October 2017

David J Adams

8

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author name string

Haruna Takeda

1

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5 October 2017

Zhubo Wei

2

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5 October 2017

Christopher Chin Kuan Yew

5

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5 October 2017

Jerrold M Ward

7

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5 October 2017

language of work or name

English

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publication date

5 January 2015

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5 October 2017

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5 October 2017

volume

47

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5 October 2017

issue

2

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5 October 2017

page(s)

142-150

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https://scigraph.springernature.com/pub.10.1038/ng.3175

5 October 2017

exact match

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cites work

Lessons from hereditary colorectal cancer

1 reference

7 January 2021

Wnt, stem cells and cancer in the intestine

1 reference

7 January 2021

Comprehensive molecular characterization of human colon and rectal cancer

1 reference

7 January 2021

The genomic landscapes of human breast and colorectal cancers

1 reference

7 January 2021

Recurrent R-spondin fusions in colon cancer

1 reference

7 January 2021

Cancer genome landscapes

1 reference

7 January 2021

Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis

1 reference

7 January 2021

A transposon-based genetic screen in mice identifies genes altered in colorectal cancer

1 reference

7 January 2021

A Sleeping Beauty transposon-mediated screen identifies murine susceptibility genes for adenomatous polyposis coli (Apc)-dependent intestinal tumorigenesis

1 reference

7 January 2021

Harnessing transposons for cancer gene discovery

1 reference

7 January 2021

Large-scale mutagenesis in p19(ARF)- and p53-deficient mice identifies cancer genes and their collaborative networks

1 reference

7 January 2021

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

1 reference

7 January 2021

Megaintestine in claudin-15-deficient mice

1 reference

7 January 2021

Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

1 reference

7 January 2021

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

1 reference

7 January 2021

A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

1 reference

7 January 2021

Signaling cross-talk between TGF-beta/BMP and other pathways

1 reference

7 January 2021

DAVID gene ID conversion tool

1 reference

7 January 2021

CK1alpha plays a central role in mediating MDM2 control of p53 and E2F-1 protein stability

1 reference

7 January 2021

Induction and activation of the p53 pathway: a role for the protein kinase CK2?

1 reference

7 January 2021

Targeting Histone Demethylases: A New Avenue for the Fight against Cancer

1 reference

7 January 2021

p53 is regulated by the lysine demethylase LSD1

1 reference

7 January 2021

Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations

1 reference

7 January 2021

Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma

1 reference

7 January 2021

Chromatin modifications and their function

1 reference

7 January 2021

Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes

1 reference

7 January 2021

ARID1A, a factor that promotes formation of SWI/SNF-mediated chromatin remodeling, is a tumor suppressor in gynecologic cancers

1 reference

7 January 2021

Srg3, a mouse homolog of BAF155, is a novel p53 target and acts as a tumor suppressor by modulating p21(WAF1/CIP1) expression.

1 reference

7 January 2021

LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation

1 reference

7 January 2021

The leucine-rich repeat protein LRIG1 is a negative regulator of ErbB family receptor tyrosine kinases

1 reference

7 January 2021

The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor

1 reference

7 January 2021

Colorectal cancer and genetic alterations in the Wnt pathway

1 reference

7 January 2021

Putative RNA-splicing gene LUC7L2 on 7q34 represents a candidate gene in pathogenesis of myeloid malignancies

1 reference

7 January 2021

LRP1B deletion in high-grade serous ovarian cancers is associated with acquired chemotherapy resistance to liposomal doxorubicin

1 reference

7 January 2021

PIK3R1 (p85α) is somatically mutated at high frequency in primary endometrial cancer

1 reference

7 January 2021

Zinc finger protein ZBTB20 is a key repressor of alpha-fetoprotein gene transcription in liver

1 reference

7 January 2021

USP10 regulates p53 localization and stability by deubiquitinating p53

1 reference

7 January 2021

Mutant p53 drives multinucleation and invasion through a process that is suppressed by ANKRD11.

1 reference

7 January 2021

Myocardin-like protein 2 regulates TGFβ signaling in embryonic stem cells and the developing vasculature.

1 reference

7 January 2021

1 reference

7 January 2021

The transcriptional coactivators megakaryoblastic leukemia 1/2 mediate the effects of loss of the tumor suppressor deleted in liver cancer 1.

1 reference

7 January 2021

Megakaryoblastic leukemia protein-1 (MKL1): Increasing evidence for an involvement in cancer progression and metastasis

1 reference

7 January 2021

MRTF-A/B suppress the oncogenic properties of v-ras- and v-src-mediated transformants

1 reference

7 January 2021

Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors

1 reference

7 January 2021

RNF43 is frequently mutated in colorectal and endometrial cancers

1 reference

7 January 2021

Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.

1 reference

7 January 2021

Sin3a acts through a multi-gene module to regulate invasion in Drosophila and human tumors

1 reference

7 January 2021

An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer

1 reference

7 January 2021

Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model

1 reference

7 January 2021

Discovery and saturation analysis of cancer genes across 21 tumour types

1 reference

7 January 2021

The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma

1 reference

7 January 2021

Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma

1 reference

7 January 2021

Identification of a novel zinc finger protein binding a conserved element critical for Pit-1-dependent growth hormone gene expression

1 reference

7 January 2021

A genetic model for colorectal tumorigenesis

1 reference

7 January 2021

Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system.

1 reference

7 January 2021

Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

1 reference

7 January 2021

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

1 reference

7 January 2021

Tissue-specific and inducible Cre-mediated recombination in the gut epithelium

1 reference

7 January 2021

Genome-wide mapping and assembly of structural variant breakpoints in the mouse genome

1 reference

7 January 2021

Novel molecular and computational methods improve the accuracy of insertion site analysis in Sleeping Beauty-induced tumors

1 reference

7 January 2021

Identifiers

DOI

10.1038/NG.3175

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Dimensions Publication ID

5 October 2017

1013370097

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