(Q41657305)

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Identification of a subset of human non-small cell lung cancer patients with high PI3Kβ and low PTEN expression, more prevalent in squamous cell carcinoma

scientific article published on 27 November 2013

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scholarly article

1 reference

Europe PubMed Central

6 October 2017

Identification of a subset of human non-small cell lung cancer patients with high PI3Kβ and low PTEN expression, more prevalent in squamous cell carcinoma (English)

1 reference

Europe PubMed Central

6 October 2017

Rebecca Ellston

6

1 reference

Europe PubMed Central

6 October 2017

Ignacio I Wistuba

16

object named as

Ignacio I Wistuba

1 reference

Europe PubMed Central

6 October 2017

author name string

Marie Cumberbatch

1

1 reference

Europe PubMed Central

6 October 2017

Ximing Tang

2

1 reference

Europe PubMed Central

6 October 2017

Garry Beran

3

1 reference

Europe PubMed Central

6 October 2017

Sonia Eckersley

4

1 reference

Europe PubMed Central

6 October 2017

Xin Wang

5

1 reference

Europe PubMed Central

6 October 2017

Simon Dearden

7

1 reference

Europe PubMed Central

6 October 2017

Sabina Cosulich

8

1 reference

Europe PubMed Central

6 October 2017

Paul D Smith

9

1 reference

Europe PubMed Central

6 October 2017

Carmen Behrens

10

1 reference

Europe PubMed Central

6 October 2017

Edward S Kim

11

1 reference

Europe PubMed Central

6 October 2017

Xinying Su

12

1 reference

Europe PubMed Central

6 October 2017

Shuqiong Fan

13

1 reference

Europe PubMed Central

6 October 2017

Neil Gray

14

1 reference

Europe PubMed Central

6 October 2017

David P Blowers

15

1 reference

Europe PubMed Central

6 October 2017

Chris Womack

17

1 reference

Europe PubMed Central

6 October 2017

language of work or name

0 references

publication date

27 November 2013

1 reference

Europe PubMed Central

6 October 2017

Clinical Cancer Research

1 reference

Europe PubMed Central

6 October 2017

20

1 reference

Europe PubMed Central

6 October 2017

3

1 reference

Europe PubMed Central

6 October 2017

595-603

1 reference

Europe PubMed Central

6 October 2017

Mutation incidence and coincidence in non small-cell lung cancer: meta-analyses by ethnicity and histology (mutMap).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

FGFR2 gene amplification in gastric cancer predicts sensitivity to the selective FGFR inhibitor AZD4547.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

Personalized therapy on the horizon for squamous cell carcinoma of the lung.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

Phosphoinositide 3-kinase (PI3K) pathway alterations are associated with histologic subtypes and are predictive of sensitivity to PI3K inhibitors in lung cancer preclinical models.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

Squamous-cell carcinomas of the lung: emerging biology, controversies, and the promise of targeted therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

Comprehensive genomic characterization of squamous cell lung cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

Divergent genomic and epigenomic landscapes of lung cancer subtypes underscore the selection of different oncogenic pathways during tumor development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

Functional characterization of an isoform-selective inhibitor of PI3K-p110β as a potential anticancer agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

Squamous cell carcinoma of the lung: molecular subtypes and therapeutic opportunities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

Signaling networks associated with AKT activation in non-small cell lung cancer (NSCLC): new insights on the role of phosphatydil-inositol-3 kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

Multi-level targeting of the phosphatidylinositol-3-kinase pathway in non-small cell lung cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

Genetic insight and therapeutic targets in squamous-cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

Cancer statistics, 2012

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

Molecular signature and pathway analysis of human primary squamous and adenocarcinoma lung cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

PTEN protein loss by immunostaining: analytic validation and prognostic indicator for a high risk surgical cohort of prostate cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

Targeted therapy in non-small-cell lung cancer--is it becoming a reality?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

The emerging mechanisms of isoform-specific PI3K signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

Isoform-specific phosphoinositide 3-kinase inhibitors exert distinct effects in solid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

Targeting the phosphoinositide 3-kinase pathway in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

Regulation of phosphoinositide 3-kinase expression in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

The differential efficacy of pemetrexed according to NSCLC histology: a review of two Phase III studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

Somatic mutations affect key pathways in lung adenocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

Class I PI3K in oncogenic cellular transformation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

PIK3CA mutations and copy number gains in human lung cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

PTEN-deficient cancers depend on PIK3CB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

The International Epidemiology of Lung Cancer: geographical distribution and secular trends.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

Essential roles of PI(3)K-p110beta in cell growth, metabolism and tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

Activating E17K mutation in the gene encoding the protein kinase AKT1 in a subset of squamous cell carcinoma of the lung

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

Mutation analysis of 24 known cancer genes in the NCI-60 cell line set.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

Throwing new light on lung cancer pathogenesis: updates on three recent topics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

Lack of PTEN expression in non-small cell lung cancer could be related to promoter methylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

6 June 2018

Loss of phosphatase and tensin homolog protein expression is an independent poor prognostic marker in lung adenocarcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

18 August 2018

PTEN mutations and relationship to EGFR, ERBB2, KRAS, and TP53 mutations in non-small cell lung cancers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

18 August 2018

High-throughput oncogene mutation profiling in human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4503252

2 December 2018

PTEN expression in non–small-cell lung cancer: evaluating its relation to tumor characteristics, allelic loss, and epigenetic alteration

1 reference

https://pubmed.ncbi.nlm.nih.gov/24284056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PTEN and phosphorylated AKT expression and prognosis in early- and late-stage non-small cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24284056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Infrequent hypermethylation of the PTEN gene in Korean non-small-cell lung cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/24284056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phospho-Akt overexpression in non-small cell lung cancer confers significant stage-independent survival disadvantage

1 reference

https://pubmed.ncbi.nlm.nih.gov/24284056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PIK3CA gene amplification in Japanese non-small cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24284056

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1078-0432.CCR-13-1638

1 reference

Europe PubMed Central

6 October 2017

1 reference

Europe PubMed Central

6 October 2017

1 reference

Europe PubMed Central

6 October 2017

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