(Q41673429)

6 October 2017

title

Identification of a novel region critical for calcineurin function in vivo and in vitro (English)

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6 October 2017

2

Cyert MS

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6 October 2017

Jiang B

1

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6 October 2017

language of work or name

English

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publication date

1 June 1999

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Journal of Biological Chemistry

6 October 2017

number of pages

9

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based on heuristic

inferred from page(s)

published in

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6 October 2017

volume

274

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6 October 2017

issue

26

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6 October 2017

page(s)

18543-18551

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Regulation of the calmodulin-stimulated protein phosphatase, calcineurin

6 October 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

FK506 and cyclosporin, molecular probes for studying intracellular signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

The Saccharomyces cerevisiae genes (CMP1 and CMP2) encoding calmodulin-binding proteins homologous to the catalytic subunit of mammalian protein phosphatase 2B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

Yeast has homologs (CNA1 and CNA2 gene products) of mammalian calcineurin, a calmodulin-regulated phosphoprotein phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

Regulatory subunit (CNB1 gene product) of yeast Ca2+/calmodulin-dependent phosphoprotein phosphatases is required for adaptation to pheromone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

The Saccharomyces cerevisiae FKS1 (ETG1) gene encodes an integral membrane protein which is a subunit of 1,3-beta-D-glucan synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

The yeast FKS1 gene encodes a novel membrane protein, mutations in which confer FK506 and cyclosporin A hypersensitivity and calcineurin-dependent growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

Calcineurin, the Ca2+/calmodulin-dependent protein phosphatase, is essential in yeast mutants with cell integrity defects and in mutants that lack a functional vacuolar H(+)-ATPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

Differential expression and function of two homologous subunits of yeast 1,3-beta-D-glucan synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

Calcineurin acts through the CRZ1/TCN1-encoded transcription factor to regulate gene expression in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

The product of HUM1, a novel yeast gene, is required for vacuolar Ca2+/H+ exchange and is related to mammalian Na+/Ca2+ exchangers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

Calcineurin inhibits VCX1-dependent H+/Ca2+ exchange and induces Ca2+ ATPases in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

Tcn1p/Crz1p, a calcineurin-dependent transcription factor that differentially regulates gene expression in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

The structure and regulation of protein phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

Kinetic and spectroscopic analyses of mutants of a conserved histidine in the metallophosphatases calcineurin and lambda protein phosphatase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

Overexpression and purification of human calcineurin alpha from Escherichia coli and assessment of catalytic functions of residues surrounding the binuclear metal center.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

Calcineurin subunit interactions: mapping the calcineurin B binding domain on calcineurin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

Calcium regulation of calcineurin phosphatase activity by its B subunit and calmodulin. Role of the autoinhibitory domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

cDNA cloning of a calcineurin B homolog in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

A rapid method for localized mutagenesis of yeast genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

A novel genetic system to detect protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

The essential mitotic target of calmodulin is the 110-kilodalton component of the spindle pole body in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

Yeast/E. coli shuttle vectors with multiple unique restriction sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

Ca2+/calmodulin-activated protein phosphatase (PP2B) of Saccharomyces cerevisiae. PP2B activity is not essential for growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

Selective inhibition of NFAT activation by a peptide spanning the calcineurin targeting site of NFAT

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

Two-site interaction of nuclear factor of activated T cells with activated calcineurin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

Functional domain structure of calcineurin A: mapping by limited proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

Characterization of the calmodulin-binding domain of calcineurin deduced from a complementary DNA clone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.26.18543

21 January 2018

Identifiers

DOI

10.1074/JBC.274.26.18543

1 reference

6 October 2017

1 reference