(Q41693862)

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Metagenomic Shotgun Sequencing and Unbiased Metabolomic Profiling Identify Specific Human Gut Microbiota and Metabolites Associated with Immune Checkpoint Therapy Efficacy in Melanoma Patients

scientific article published on 14 September 2017

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scholarly article

1 reference

Europe PubMed Central

7 October 2017

Metagenomic Shotgun Sequencing and Unbiased Metabolomic Profiling Identify Specific Human Gut Microbiota and Metabolites Associated with Immune Checkpoint Therapy Efficacy in Melanoma Patients (English)

1 reference

Europe PubMed Central

7 October 2017

1 reference

based on heuristic

inferred from title

metabolomic profiling

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Arthur E. Frankel

1

object named as

Arthur E Frankel

1 reference

Europe PubMed Central

7 October 2017

author name string

Laura A Coughlin

2

1 reference

Europe PubMed Central

7 October 2017

Jiwoong Kim

3

1 reference

Europe PubMed Central

7 October 2017

Thomas W Froehlich

4

1 reference

Europe PubMed Central

7 October 2017

Yang Xie

5

1 reference

Europe PubMed Central

7 October 2017

Eugene P Frenkel

6

1 reference

Europe PubMed Central

7 October 2017

Andrew Y Koh

7

1 reference

Europe PubMed Central

7 October 2017

publication date

14 September 2017

1 reference

Europe PubMed Central

7 October 2017

1 reference

Europe PubMed Central

7 October 2017

19

1 reference

Europe PubMed Central

7 October 2017

10

1 reference

Europe PubMed Central

7 October 2017

848-855

1 reference

Europe PubMed Central

7 October 2017

Baseline gut microbiota predicts clinical response and colitis in metastatic melanoma patients treated with ipilimumab

1 reference

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Anacardic Acid Constituents from Cashew Nut Shell Liquid: NMR Characterization and the Effect of Unsaturation on Its Biological Activities

1 reference

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Intestinal Microbiota and Relapse After Hematopoietic-Cell Transplantation.

1 reference

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Antibiotic-Induced Depletion of Anti-inflammatory Clostridia Is Associated with the Development of Graft-versus-Host Disease in Pediatric Stem Cell Transplantation Patients

1 reference

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cGAS is essential for the antitumor effect of immune checkpoint blockade

1 reference

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Human melanomas and ovarian cancers overexpressing mechanical barrier molecule genes lack immune signatures and have increased patient mortality risk

1 reference

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Predictive biomarkers for checkpoint inhibitor-based immunotherapy

1 reference

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FMAP: Functional Mapping and Analysis Pipeline for metagenomics and metatranscriptomics studies

1 reference

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Combined nivolumab and ipilimumab versus ipilimumab alone in patients with advanced melanoma: 2-year overall survival outcomes in a multicentre, randomised, controlled, phase 2 trial

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Preclinical Development of Ipilimumab and Nivolumab Combination Immunotherapy: Mouse Tumor Models, In Vitro Functional Studies, and Cynomolgus Macaque Toxicology

1 reference

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Critical Role for CD103(+)/CD141(+) Dendritic Cells Bearing CCR7 for Tumor Antigen Trafficking and Priming of T Cell Immunity in Melanoma

1 reference

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Severe Gut Microbiota Dysbiosis Is Associated With Poor Growth in Patients With Short Bowel Syndrome

1 reference

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16S rRNA gene sequencing of mock microbial populations- impact of DNA extraction method, primer choice and sequencing platform

1 reference

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Natural Product Anacardic Acid from Cashew Nut Shells Stimulates Neutrophil Extracellular Trap Production and Bactericidal Activity

1 reference

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Fecal Microbiota, Fecal Metabolome, and Colorectal Cancer Interrelations

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Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota

1 reference

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Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy

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The anacardic 6-pentadecyl salicylic acid induces macrophage activation via the phosphorylation of ERK1/2, JNK, P38 kinases and NF-κB.

1 reference

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Primer and platform effects on 16S rRNA tag sequencing

1 reference

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6 June 2018

Immune-Related Adverse Events, Need for Systemic Immunosuppression, and Effects on Survival and Time to Treatment Failure in Patients With Melanoma Treated With Ipilimumab at Memorial Sloan Kettering Cancer Center

1 reference

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Activation of HIF-1α and LL-37 by commensal bacteria inhibits Candida albicans colonization

1 reference

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6 June 2018

Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5602478

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Colitogenic Bacteroides thetaiotaomicron Antigens Access Host Immune Cells in a Sulfatase-Dependent Manner via Outer Membrane Vesicles

1 reference

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Fate, activity, and impact of ingested bacteria within the human gut microbiota

1 reference

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Molecular control of PtdIns(3,4,5)P3 signaling in neutrophils

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Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile.

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Evaluating bias of illumina-based bacterial 16S rRNA gene profiles

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Diet rapidly and reproducibly alters the human gut microbiome

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Commensal bacteria control cancer response to therapy by modulating the tumor microenvironment.

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The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis

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Nivolumab plus ipilimumab in advanced melanoma

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Collateral effects of antibiotics on mammalian gut microbiomes

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Metabolic reconstruction for metagenomic data and its application to the human microbiome

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Interactions between the microbiota and the immune system

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6 June 2018

Identifiers

10.1016/J.NEO.2017.08.004

1 reference

Europe PubMed Central

7 October 2017

1 reference

Europe PubMed Central

7 October 2017

1 reference

Europe PubMed Central

7 October 2017

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