(Q41751563)

8 October 2017

1 reference

title

Metabolism of presenilin 1: influence of presenilin 1 on amyloid precursor protein processing (English)

1 reference

8 October 2017

Borchelt DR

1

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8 October 2017

1 January 1998

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8 October 2017

Neurobiology of Aging

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8 October 2017

19

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8 October 2017

1 Suppl

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8 October 2017

S15-8

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Human presenilin-1, but not familial Alzheimer's disease (FAD) mutants, facilitate Caenorhabditis elegans Notch signalling independently of proteolytic processing.

8 October 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2898%2900026-8

7 January 2021

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2898%2900026-8

7 January 2021

Release of excess amyloid beta protein from a mutant amyloid beta protein precursor.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2898%2900026-8

7 January 2021

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2898%2900026-8

7 January 2021

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2898%2900026-8

7 January 2021

Protein topology of presenilin 1

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2898%2900026-8

7 January 2021

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2898%2900026-8

7 January 2021

Amyloid beta protein (A beta) in Alzheimer's disease brain. Biochemical and immunocytochemical analysis with antibodies specific for forms ending at A beta 40 or A beta 42(43).

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2898%2900026-8

7 January 2021

Presenilins: genes for life and death

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2898%2900026-8

7 January 2021

Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2898%2900026-8

7 January 2021

The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2898%2900026-8

7 January 2021

Expression of presenilin 1 and 2 (PS1 and PS2) in human and murine tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2898%2900026-8

7 January 2021

The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2898%2900026-8

7 January 2021

Assessment of normal and mutant human presenilin function in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2898%2900026-8

7 January 2021

Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2898%2900026-8

7 January 2021

Candidate gene for the chromosome 1 familial Alzheimer's disease locus

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2898%2900026-8

7 January 2021

Membrane topology of the C. elegans SEL-12 presenilin

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2898%2900026-8

7 January 2021

Characterization of human presenilin 1 using N-terminal specific monoclonal antibodies: Evidence that Alzheimer mutations affect proteolytic processing.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2898%2900026-8

7 January 2021

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2898%2900026-8

7 January 2021

Genetic dissection of Alzheimer disease, a heterogeneous disorder

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2898%2900026-8

7 January 2021

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2898%2900026-8

7 January 2021

Amyloid beta-protein and the genetics of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2898%2900026-8

7 January 2021

Alzheimer's disease associated with mutations in presenilin 2 is rare and variably penetrant.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2898%2900026-8

7 January 2021

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2898%2900026-8

7 January 2021

Nucleotide sequence of the chromosome 14-encodedS182cDNA and revised secondary structure prediction

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2898%2900026-8

7 January 2021

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2898%2900026-8

7 January 2021

Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2898%2900026-8

7 January 2021

10.1016/S0197-4580(98)00026-8

Identifiers

DOI

1 reference

8 October 2017

1 reference

PubMed ID

9562461