(Q41844700)

English

A candidate anti-HIV reservoir compound, auranofin, exerts a selective 'anti-memory' effect by exploiting the baseline oxidative status of lymphocytes.

scientific article published on 5 December 2013

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24309931%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

A candidate anti-HIV reservoir compound, auranofin, exerts a selective 'anti-memory' effect by exploiting the baseline oxidative status of lymphocytes (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24309931%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Rossella Sgarbanti

2

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2 March 2020

Barbara Chirullo

1

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2 March 2020

Dolores Limongi

3

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2 March 2020

4

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2 March 2020

Nicolas Chomont

9

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2 March 2020

13

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2 March 2020

Anna Teresa Palamara

16

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2 March 2020

author name string

D Alvarez

5

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2 March 2020

B Das

6

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2 March 2020

A Boe

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2 March 2020

S DaFonseca

8

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2 March 2020

L Liotta

10

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2 March 2020

E Iii Petricoin

11

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2 March 2020

S Norelli

12

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2 March 2020

E Garaci

14

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2 March 2020

A Savarino

15

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2 March 2020

publication date

5 December 2013

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2 March 2020

Cell Death and Disease

1 reference

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2 March 2020

4

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2 March 2020

e944

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2 March 2020

copyright license

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

1 December 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Highlights on HIV eradication in 2013.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

6 June 2018

Investigational treatment suspension and enhanced cell-mediated immunity at rebound followed by drug-free remission of simian AIDS.

1 reference

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6 June 2018

Altering cell death pathways as an approach to cure HIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

6 June 2018

Olaquindox-induced apoptosis is suppressed through p38 MAPK and ROS-mediated JNK pathways in HepG2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

6 June 2018

Cadmium induces apoptosis in pancreatic β-cells through a mitochondria-dependent pathway: the role of oxidative stress-mediated c-Jun N-terminal kinase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

6 June 2018

Enhancement of auranofin-induced apoptosis in MCF-7 human breast cells by selenocystine, a synergistic inhibitor of thioredoxin reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

6 June 2018

Therapeutic imprinting of the immune system: towards a remission of AIDS in primates?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

6 June 2018

The development of immune-modulating compounds to disrupt HIV latency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

6 June 2018

A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

6 June 2018

Eliminating the HIV reservoir

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

6 June 2018

p38(MAPK) and ERK1/2 dictate cell death/survival response to different pro-oxidant stimuli via p53 and Nrf2 in neuroblastoma cells SH-SY5Y.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

6 June 2018

HIV reservoirs and the possibility of a cure for HIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

6 June 2018

Superoxide dismutase in redox biology: the roles of superoxide and hydrogen peroxide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

6 June 2018

Maintenance of CD4+ T-cell memory and HIV persistence: keeping memory, keeping HIV.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

6 June 2018

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

6 June 2018

The thioredoxin reductase inhibitor auranofin triggers apoptosis through a Bax/Bak-dependent process that involves peroxiredoxin 3 oxidation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

6 June 2018

A portrait of tissue phosphoprotein stability in the clinical tissue procurement process

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

6 June 2018

Auranofin inhibits overproduction of pro-inflammatory cytokines, cyclooxygenase expression and PGE2 production in macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

6 June 2018

Fluorescent and luminescent probes for measurement of oxidative and nitrosative species in cells and tissues: progress, pitfalls, and prospects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

6 June 2018

Redox control of apoptosis: an update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

6 June 2018

Reactive oxygen species-induced activation of the MAP kinase signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

6 June 2018

Membrane accumulation of influenza A virus hemagglutinin triggers nuclear export of the viral genome via protein kinase Calpha-mediated activation of ERK signaling

1 reference

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6 June 2018

p38 mitogen-activated protein kinase mediates the Fas-induced mitochondrial death pathway in CD8+ T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

6 June 2018

Auranofin induces apoptosis and when combined with retinoic acid enhances differentiation of acute promyelocytic leukaemia cells in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

6 June 2018

Chrysotherapy: a synoptic review

1 reference

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6 June 2018

Persistent immune activation in HIV-1 infection is associated with progression to AIDS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

6 June 2018

Induction of mitochondrial permeability transition by auranofin, a gold(I)-phosphine derivative

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

6 June 2018

Reactive oxygen species, antioxidants, and the mammalian thioredoxin system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

6 June 2018

Inhibition of interleukin-12 production by auranofin, an anti-rheumatic gold compound, deviates CD4(+) T cells from the Th1 to the Th2 pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

6 June 2018

Arsenicals inhibit thioredoxin reductase in cultured rat hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

6 June 2018

The p38 signal transduction pathway: activation and function

1 reference

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6 June 2018

Glutathione and its role in cellular functions

1 reference

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6 June 2018

MAP kinase pathways

1 reference

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6 June 2018

Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy

1 reference

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6 June 2018

1 reference

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6 June 2018

Signal transduction by lymphocyte antigen receptors

1 reference

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How MAP kinases are regulated

1 reference

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The regulation of AP-1 activity by mitogen-activated protein kinases

1 reference

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6 June 2018

Gold drug auranofin restricts the viral reservoir in the monkey AIDS model and induces containment of viral load following ART suspension.

1 reference

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Elite controllers display higher activation on central memory CD8 T cells than HIV patients successfully on HAART.

1 reference

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18 August 2018

Gold(I) complexes determine apoptosis with limited oxidative stress in Jurkat T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

18 August 2018

Preferential cell death of CD8+ effector memory (CCR7-CD45RA-) T cells by hydrogen peroxide-induced oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

18 August 2018

Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3877546

18 August 2018

A hypothesis on the catalytic mechanism of the selenoenzyme thioredoxin reductase

1 reference

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18 August 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2013.473

21 January 2018

Bcl-2 Phosphorylation by p38 MAPK

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2013.473

21 January 2018

Synergistic inhibition of T cell proliferation by gold sodium thiomalate and auranofin

1 reference

https://pubmed.ncbi.nlm.nih.gov/24309931

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LXXIII.—Oxidation of tartaric acid in presence of iron

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2013.473

7 January 2021

based on heuristic

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Identifiers

10.1038/CDDIS.2013.473

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24309931%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

PMC publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24309931%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24309931%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

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