(Q34583903)

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Cadmium induces apoptosis in pancreatic β-cells through a mitochondria-dependent pathway: the role of oxidative stress-mediated c-Jun N-terminal kinase activation

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

Cadmium induces apoptosis in pancreatic β-cells through a mitochondria-dependent pathway: the role of oxidative stress-mediated c-Jun N-terminal kinase activation (English)

1 reference

Europe PubMed Central

3 August 2017

1 reference

based on heuristic

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object named as

Shing-Hwa Liu

3

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author name string

Kai-Chih Chang

1

1 reference

Europe PubMed Central

3 August 2017

Ching-Cheng Hsu

2

1 reference

Europe PubMed Central

3 August 2017

Chin-Chuan Su

4

1 reference

Europe PubMed Central

3 August 2017

Cheng-Chieh Yen

5

1 reference

Europe PubMed Central

3 August 2017

Ming-Jye Lee

6

1 reference

Europe PubMed Central

3 August 2017

Kuo-Liang Chen

7

1 reference

Europe PubMed Central

3 August 2017

Tsung-Jung Ho

8

1 reference

Europe PubMed Central

3 August 2017

Dong-Zong Hung

9

1 reference

Europe PubMed Central

3 August 2017

Chin-Ching Wu

10

1 reference

Europe PubMed Central

3 August 2017

Tien-Hui Lu

11

1 reference

Europe PubMed Central

3 August 2017

Yi-Chang Su

12

1 reference

Europe PubMed Central

3 August 2017

Ya-Wen Chen

13

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Europe PubMed Central

3 August 2017

Chun-Fa Huang

14

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Europe PubMed Central

3 August 2017

language of work or name

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publication date

6 February 2013

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Europe PubMed Central

3 August 2017

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Europe PubMed Central

3 August 2017

8

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Europe PubMed Central

3 August 2017

e54374

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Europe PubMed Central

3 August 2017

2

1 reference

Europe PubMed Central

3 August 2017

copyright license

Creative Commons Attribution 4.0 International

6 February 2013

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April 2022 Public Data File from Crossref

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Calcium signaling is involved in cadmium-induced neuronal apoptosis via induction of reactive oxygen species and activation of MAPK/mTOR network.

1 reference

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7 July 2018

Inorganic arsenic causes cell apoptosis in mouse cerebrum through an oxidative stress-regulated signaling pathway

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7 July 2018

Advances in metal-induced oxidative stress and human disease

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7 July 2018

Oxidative stress, insulin signaling, and diabetes.

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7 July 2018

Heavy metals, islet function and diabetes development

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MAPK signalling in cellular metabolism: stress or wellness?

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Oxidative stress, nitric oxide, and diabetes

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7 July 2018

Mitochondria, reactive oxygen species and cadmium toxicity in the kidney

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Mitochondrial signaling in cell death via the Bcl-2 family

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Pathological roles of MAPK signaling pathways in human diseases

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Cadmium induces intracellular Ca2+- and H2O2-dependent apoptosis through JNK- and p53-mediated pathways in skin epidermal cell line

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Current status of cadmium as an environmental health problem

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Cadmium, diabetes and chronic kidney disease

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Cadmium & its adverse effects on human health.

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Targeting p53 to mitochondria for cancer therapy

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Diabetes associated cell stress and dysfunction: role of mitochondrial and non-mitochondrial ROS production and activity

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7 July 2018

Free radicals and antioxidants in normal physiological functions and human disease

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7 July 2018

The role of phosphoinositide 3-kinase/Akt signaling in low-dose mercury-induced mouse pancreatic beta-cell dysfunction in vitro and in vivo

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7 July 2018

Oxidative stress and pancreatic beta-cell dysfunction

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7 July 2018

Identification of ASK1, MKK4, JNK, c-Jun, and caspase-3 as a signaling cascade involved in cadmium-induced neuronal cell apoptosis

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7 July 2018

Cadmium induces caspase-independent apoptosis in liver Hep3B cells: role for calcium in signaling oxidative stress-related impairment of mitochondria and relocation of endonuclease G and apoptosis-inducing factor

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7 July 2018

Hazards of heavy metal contamination

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7 July 2018

Mechanisms of cytochrome c release by proapoptotic BCL-2 family members

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7 July 2018

Mitochondrial reactive oxygen species reduce insulin secretion by pancreatic beta-cells

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7 July 2018

Relative expression software tool (REST©) for group-wise comparison and statistical analysis of relative expression results in real-time PCR

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Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions

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Mammalian MAP kinase signalling cascades

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Cadmium- and chromium-induced oxidative stress, DNA damage, and apoptotic cell death in cultured human chronic myelogenous leukemic K562 cells, promyelocytic leukemic HL-60 cells, and normal human peripheral blood mononuclear cells

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A model for p53-induced apoptosis

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Diabetogenic effects of chronic oral cadmium adminstration to neonatal rats

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Effect of multiple doses of cadmium on glucose metabolism and insulin secretion in the rat

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Isolation of major pancreatic cell types and long-term culture-initiating cells using novel human surface markers.

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Striking association between urinary cadmium level and albuminuria among Torres Strait Islander people with diabetes

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Urinary cadmium, impaired fasting glucose, and diabetes in the NHANES III.

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Reactive oxygen species-mediated pancreatic beta-cell death is regulated by interactions between stress-activated protein kinases, p38 and c-Jun N-terminal kinase, and mitogen-activated protein kinase phosphatases.

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The MAPK kinase kinase-1 is essential for stress-induced pancreatic islet cell death

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Initiation of caspase-independent death in mouse mesangial cells by Cd2+: involvement of p38 kinase and CaMK-II.

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Cadmium induces impaired glucose tolerance in rat by down-regulating GLUT4 expression in adipocytes.

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Identifiers

10.1371/JOURNAL.PONE.0054374

1 reference

Europe PubMed Central

3 August 2017

2013PLoSO...854374C

0 references

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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