(Q41852502)

13 October 2017

Common variants in WFS1 confer risk of type 2 diabetes (English)

1 reference

13 October 2017

0 references

24

Inês Barroso

1 reference

13 October 2017

Katherine A Fawcett

3

0 references

Richard Sherva

Richard Sherva

10

0 references

Hana Lango Allen

Hana Lango

7

0 references

Benjamin Glaser

Benjamin Glaser

20

0 references

Michael N Weedon

Michael N Weedon

2

0 references

Mark McCarthy

Mark I McCarthy

17

0 references

Nicholas J. Wareham

23

Nicholas J Wareham

1 reference

13 October 2017

12

Paul D Pharoah

1 reference

13 October 2017

Andrew Tym Hattersley

22

Andrew T Hattersley

1 reference

13 October 2017

8

Timothy M Frayling

1 reference

13 October 2017

16

Andrew D Morris

1 reference

13 October 2017

Manjinder S Sandhu

1

1 reference

13 October 2017

Jon Wasson

4

1 reference

13 October 2017

Sally L Debenham

5

1 reference

13 October 2017

Allan Daly

6

1 reference

13 October 2017

Rosalind J Neumann

9

1 reference

13 October 2017

Ilana Blech

11

1 reference

13 October 2017

Colin N A Palmer

13

1 reference

13 October 2017

Charlotte Kimber

14

1 reference

13 October 2017

Roger Tavendale

15

1 reference

13 October 2017

Mark Walker

18

1 reference

13 October 2017

Graham Hitman

19

1 reference

13 October 2017

M Alan Permutt

21

1 reference

13 October 2017

language of work or name

English

0 references

publication date

1 July 2007

1 reference

13 October 2017

1 reference

13 October 2017

39

1 reference

13 October 2017

8

1 reference

13 October 2017

951-953

1 reference

Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes

13 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672152

WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic beta-cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672152

Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672152

The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672152

Diabetes insipidus, diabetes mellitus, optic atrophy and deafness (DIDMOAD) caused by mutations in a novel gene (wolframin) coding for a predicted transmembrane protein

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672152

A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome)

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672152

Mice conditionally lacking the Wolfram gene in pancreatic islet beta cells exhibit diabetes as a result of enhanced endoplasmic reticulum stress and apoptosis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672152

Disruption of the WFS1 gene in mice causes progressive beta-cell loss and impaired stimulus-secretion coupling in insulin secretion

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672152

Genetic variation near the hepatocyte nuclear factor-4 alpha gene predicts susceptibility to type 2 diabetes

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672152

A common polymorphism in the upstream promoter region of the hepatocyte nuclear factor-4 alpha gene on chromosome 20q is associated with type 2 diabetes and appears to contribute to the evidence for linkage in an ashkenazi jewish population.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672152

The E23K variant of Kir6.2 associates with impaired post-OGTT serum insulin response and increased risk of type 2 diabetes

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672152

Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672152

Association Studies of Genetic Variation in the WFS1 Gene and Type 2 Diabetes in U.K. Populations

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17603484

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Genetically programmed selective islet beta-cell loss in diabetic subjects with Wolfram's syndrome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17603484

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NG2067

1 reference

Dimensions Publication ID

13 October 2017

0 references

1 reference

13 October 2017

PubMed publication ID

17603484

1 reference