(Q41883034)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26095671%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

title

The exonuclease activity of DNA polymerase γ is required for ligation during mitochondrial DNA replication (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26095671%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

0 references

2

1 reference

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17 February 2020

James Bruce Stewart

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26095671%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Claes M Gustafsson

9

0 references

author name string

Bertil Macao

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26095671%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Triinu Siibak

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26095671%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Xuefeng Zhu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26095671%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Yonghong Shi

5

1 reference

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17 February 2020

Wenwen Sheng

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26095671%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Monica Olsson

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26095671%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Maria Falkenberg

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26095671%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

language of work or name

English

0 references

publication date

22 June 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26095671%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

published in

Nature Communications

1 reference

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17 February 2020

volume

6

1 reference

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17 February 2020

page(s)

7303

1 reference

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Creative Commons Attribution 4.0 International

17 February 2020

copyright license

start time

22 June 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/ncomms8303

0 references

cites work

In vivo occupancy of mitochondrial single-stranded DNA binding protein supports the strand displacement mode of DNA replication

1 reference

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Linear mtDNA fragments and unusual mtDNA rearrangements associated with pathological deficiency of MGME1 exonuclease

5 June 2018

1 reference

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Simultaneous quantification of mitochondrial DNA copy number and deletion ratio: a multiplex real-time PCR assay

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557304

Exonuclease of human DNA polymerase gamma disengages its strand displacement function

5 June 2018

1 reference

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Clinical and molecular features of POLG-related mitochondrial disease.

5 June 2018

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5 June 2018

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Identification of a novel human mitochondrial endo-/exonuclease Ddk1/c20orf72 necessary for maintenance of proper 7S DNA levels

5 June 2018

1 reference

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Loss-of-function mutations in MGME1 impair mtDNA replication and cause multisystemic mitochondrial disease

5 June 2018

1 reference

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Apoptosis induced by persistent single-strand breaks in mitochondrial genome: critical role of EXOG (5'-EXO/endonuclease) in their repair

5 June 2018

1 reference

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Okazaki fragment maturation: nucleases take centre stage

5 June 2018

1 reference

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The mitochondrial DNA 4,977-bp deletion and its implication in copy number alteration in colorectal cancer.

5 June 2018

1 reference

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Sequence-specific stalling of DNA polymerase γ and the effects of mutations causing progressive ophthalmoplegia

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557304

Eukaryotic lagging strand DNA replication employs a multi-pathway mechanism that protects genome integrity

5 June 2018

1 reference

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Mitochondrial DNA replication and disease: insights from DNA polymerase γ mutations

5 June 2018

1 reference

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A cluster of pathogenic mutations in the 3'-5' exonuclease domain of DNA polymerase gamma defines a novel module coupling DNA synthesis and degradation

5 June 2018

1 reference

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Human Dna2 is a nuclear and mitochondrial DNA maintenance protein

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557304

Mitochondrial DNA mutations and ageing

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557304

Mice expressing an error-prone DNA polymerase in mitochondria display elevated replication pausing and chromosomal breakage at fragile sites of mitochondrial DNA.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557304

Human DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediates

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557304

Removal of oxidative DNA damage via FEN1-dependent long-patch base excision repair in human cell mitochondria

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557304

What causes mitochondrial DNA deletions in human cells?

5 June 2018

1 reference

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EXOG, a novel paralog of Endonuclease G in higher eukaryotes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557304

DNA replication and transcription in mammalian mitochondria

5 June 2018

1 reference

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Early embryonic lethality due to targeted inactivation of DNA ligase III

5 June 2018

1 reference

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High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557304

Consequences of mutations in human DNA polymerase gamma.

5 June 2018

1 reference

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Idling by DNA polymerase delta maintains a ligatable nick during lagging-strand DNA replication

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557304

Reconstitution of a minimal mtDNA replisome in vitro

5 June 2018

1 reference

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Premature ageing in mice expressing defective mitochondrial DNA polymerase

5 June 2018

1 reference

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3' to 5' exonuclease activity of herpes simplex virus type 1 DNA polymerase modulates its strand displacement activity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557304

Okazaki fragment maturation in yeast. II. Cooperation between the polymerase and 3'-5'-exonuclease activities of Pol delta in the creation of a ligatable nick

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557304

Okazaki fragment processing: modulation of the strand displacement activity of DNA polymerase delta by the concerted action of replication protein A, proliferating cell nuclear antigen, and flap endonuclease-1.

5 June 2018

1 reference

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Bacteriophage T4 RNase H removes both RNA primers and adjacent DNA from the 5' end of lagging strand fragments

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557304

The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557304

Replication slippage of different DNA polymerases is inversely related to their strand displacement efficiency

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557304

The human DNA ligase III gene encodes nuclear and mitochondrial proteins

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557304

Mitochondrial DNA maintenance in vertebrates

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557304

Replication of mitochondrial DNA. Circular replicative intermediates in mouse L cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557304

DNA sequence analysis with a modified bacteriophage T7 DNA polymerase

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557304

Patterns of mitochondrial DNA damage in blood and brain tissues of a transgenic mouse model of Machado-Joseph disease.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557304

Mitochondrial DNA polymerase gamma mutations: an ever expanding molecular and clinical spectrum.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557304

The accessory subunit B of DNA polymerase gamma is required for mitochondrial replisome function

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557304

Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557304

Two forms of the DNA polymerase of bacteriophage T7.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557304

Mitochondrial RNA polymerase is needed for activation of the origin of light-strand DNA replication

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26095671

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCOMMS8303

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26095671%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26095671%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

PubMed publication ID

26095671

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26095671%20AND%20SRC:MED&resulttype=core&format=json