(Q41891240)

13 October 2017

Lowered H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas (English)

1 reference

13 October 2017

Jill Bayliss

1

0 references

Peter W. Lewis

Peter W Lewis

18

0 references

Cynthia Hawkins

19

Cynthia Hawkins

1 reference

13 October 2017

Siddhant U Jain

4

0 references

Pooja Panwalkar

Pooja Panwalkar

9

0 references

Charles David Allis

21

C David Allis

1 reference

13 October 2017

22

Craig B Thompson

1 reference

13 October 2017

Piali Mukherjee

2

1 reference

13 October 2017

Chao Lu

3

1 reference

13 October 2017

Chan Chung

5

1 reference

13 October 2017

Daniel Martinez

6

1 reference

13 October 2017

Benjamin Sabari

7

1 reference

13 October 2017

Ashley S Margol

8

1 reference

13 October 2017

Abhijit Parolia

10

1 reference

13 October 2017

Melike Pekmezci

11

1 reference

13 October 2017

Richard C McEachin

12

1 reference

13 October 2017

Marcin Cieslik

13

1 reference

13 October 2017

Benita Tamrazi

14

1 reference

13 October 2017

Benjamin A Garcia

15

1 reference

13 October 2017

Gaspare La Rocca

16

1 reference

13 October 2017

Mariarita Santi

17

1 reference

13 October 2017

Ari Melnick

20

1 reference

13 October 2017

Arul M Chinnaiyan

23

1 reference

13 October 2017

Alexander R Judkins

24

1 reference

13 October 2017

Sriram Venneti

25

1 reference

13 October 2017

language of work or name

English

0 references

publication date

1 November 2016

1 reference

Science Translational Medicine

13 October 2017

1 reference

13 October 2017

8

1 reference

13 October 2017

366

1 reference

13 October 2017

366ra161

1 reference

Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis

13 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

Molecular identity of human outer radial glia during cortical development

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

Lhx2 regulates the timing of β-catenin-dependent cortical neurogenesis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

Regulation of chromatin accessibility and Zic binding at enhancers in the developing cerebellum

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

Coevolution of radial glial cells and the cerebral cortex

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

EZH2 expression is a prognostic factor in childhood intracranial ependymoma: a Canadian Pediatric Brain Tumor Consortium study

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

Use of human embryonic stem cells to model pediatric gliomas with H3.3K27M histone mutation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

Radial glia require PDGFD-PDGFRβ signalling in human but not mouse neocortex.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

Epigenomic alterations define lethal CIMP-positive ependymomas of infancy

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

C11orf95-RELA fusions drive oncogenic NF-κB signalling in ependymoma

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

Redistribution of H3K27me3 upon DNA hypomethylation results in de-repression of Polycomb target genes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

Evaluation of histone 3 lysine 27 trimethylation (H3K27me3) and enhancer of Zest 2 (EZH2) in pediatric glial and glioneuronal tumors shows decreased H3K27me3 in H3F3A K27M mutant glioblastomas

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

GC-rich sequence elements recruit PRC2 in mammalian ES cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

Cross-species genomics matches driver mutations and cell compartments to model ependymoma

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

Identification of novel glial genes by single-cell transcriptional profiling of Bergmann glial cells from mouse cerebellum

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

The 2007 WHO classification of tumours of the central nervous system

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

Radial glia cells are candidate stem cells of ependymoma

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

Zebrafish Dmrta2 regulates neurogenesis in the telencephalon.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

Primary postoperative chemotherapy without radiotherapy for intracranial ependymoma in children: the UKCCSG/SIOP prospective study.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

Preliminary results from a phase II trial of conformal radiation therapy and evaluation of radiation-related CNS effects for pediatric patients with localized ependymoma

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5123566

10.1126/SCITRANSLMED.AAH6904

18 August 2018

Identifiers

DOI

1 reference

13 October 2017

1 reference

13 October 2017

1 reference