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Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson's disease.
scientific article published on 17 January 2013
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scholarly article
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Europe PubMed Central
PMC publication ID
3563993
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23328674%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
title
Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson's disease
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3563993
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23328674%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
main subject
Trap1 Dmel_CG3152
1 reference
stated in
GOA release 2020-03-11
Parkinson's disease
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based on heuristic
inferred from title
author
L. Miguel Martins
series ordinal
3
1 reference
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Europe PubMed Central
PMC publication ID
3563993
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23328674%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
author name string
A C Costa
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3563993
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23328674%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
S H Y Loh
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3563993
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23328674%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
publication date
17 January 2013
1 reference
stated in
Europe PubMed Central
PMC publication ID
3563993
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23328674%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
published in
Cell Death and Disease
1 reference
stated in
Europe PubMed Central
PMC publication ID
3563993
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23328674%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
volume
4
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stated in
Europe PubMed Central
PMC publication ID
3563993
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23328674%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
page(s)
e467
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Europe PubMed Central
PMC publication ID
3563993
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23328674%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
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PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
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The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila
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The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1.
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Mitochondrial chaperone tumour necrosis factor receptor-associated protein 1 protects cardiomyocytes from hypoxic injury by regulating mitochondrial permeability transition pore opening
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TRAP1, a novel mitochondrial chaperone responsible for multi-drug resistance and protection from apoptotis in human colorectal carcinoma cells
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Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response
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18 August 2018
Heat shock protein 75 (TRAP1) antagonizes reactive oxygen species generation and protects cells from granzyme M-mediated apoptosis.
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18 August 2018
The Drosophila parkin homologue is required for normal mitochondrial dynamics during spermiogenesis
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Dense-cored vesicles, smooth endoplasmic reticulum, and mitochondria are closely associated with non-specialized parts of plasma membrane of nerve terminals: implications for exocytosis and calcium buffering by intraterminal organelles
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retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1038/CDDIS.2012.205
1 reference
stated in
Europe PubMed Central
PMC publication ID
3563993
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23328674%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
PMC publication ID
3563993
1 reference
stated in
Europe PubMed Central
PMC publication ID
3563993
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23328674%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
PubMed publication ID
23328674
1 reference
stated in
Europe PubMed Central
PMC publication ID
3563993
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23328674%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
ResearchGate publication ID
234161084
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