(Q41893732)

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Hepatocyte growth factor and sonic Hedgehog expression in cerebellar neural progenitor cells costimulate medulloblastoma initiation and growth

scientific article published on October 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Hepatocyte growth factor and sonic Hedgehog expression in cerebellar neural progenitor cells costimulate medulloblastoma initiation and growth (English)

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

medulloblastoma

0 references

Charles G Eberhart

5

object named as

Charles G Eberhart

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

author name string

Mandy J Binning

1

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Toba Niazi

2

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Carolyn A Pedone

3

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Bachchu Lal

4

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

K Jin Kim

6

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

John Laterra

7

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Daniel W Fults

8

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

language of work or name

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publication date

1 October 2008

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Cancer Research

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

68

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

19

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

7838-7845

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

c-Met inhibitors with novel binding mode show activity against several hereditary papillary renal cell carcinoma-related mutations

1 reference

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5 June 2018

AMG 102, a fully human anti-hepatocyte growth factor/scatter factor neutralizing antibody, enhances the efficacy of temozolomide or docetaxel in U-87 MG cells and xenografts

1 reference

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5 June 2018

A novel one-armed anti-c-Met antibody inhibits glioblastoma growth in vivo

1 reference

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5 June 2018

Systemic anti-hepatocyte growth factor monoclonal antibody therapy induces the regression of intracranial glioma xenografts

1 reference

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5 June 2018

Fully human monoclonal antibodies to hepatocyte growth factor with therapeutic potential against hepatocyte growth factor/c-Met-dependent human tumors

1 reference

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5 June 2018

The scatter factor/hepatocyte growth factor: c-met pathway in human embryonal central nervous system tumor malignancy

1 reference

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5 June 2018

Scatter factor/hepatocyte growth factor in brain tumor growth and angiogenesis

1 reference

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Morphing into cancer: the role of developmental signaling pathways in brain tumor formation

1 reference

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5 June 2018

The SmoA1 mouse model reveals that notch signaling is critical for the growth and survival of sonic hedgehog-induced medulloblastomas

1 reference

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5 June 2018

Current treatment of medulloblastoma: recent advances and future challenges

1 reference

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5 June 2018

Targeting the tumor and its microenvironment by a dual-function decoy Met receptor

1 reference

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5 June 2018

Sonic hedgehog and insulin-like growth factor signaling synergize to induce medulloblastoma formation from nestin-expressing neural progenitors in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2638505

5 June 2018

Met, metastasis, motility and more

1 reference

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5 June 2018

Potent and selective inhibitors of the Met [hepatocyte growth factor/scatter factor (HGF/SF) receptor] tyrosine kinase block HGF/SF-induced tumor cell growth and invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2638505

5 June 2018

Reduced c-Met expression by an adenovirus expressing a c-Met ribozyme inhibits tumorigenic growth and lymph node metastases of PC3-LN4 prostate tumor cells in an orthotopic nude mouse model

1 reference

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5 June 2018

A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2638505

5 June 2018

c-Myc enhances sonic hedgehog-induced medulloblastoma formation from nestin-expressing neural progenitors in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2638505

5 June 2018

Viable hypomorphic signaling mutant of the Met receptor reveals a role for hepatocyte growth factor in postnatal cerebellar development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2638505

5 June 2018

Neuroprotection by scatter factor/hepatocyte growth factor and FGF-1 in cerebellar granule neurons is phosphatidylinositol 3-kinase/akt-dependent and MAPK/CREB-independent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2638505

5 June 2018

Prediction of central nervous system embryonal tumour outcome based on gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2638505

5 June 2018

Neutralizing monoclonal antibodies to hepatocyte growth factor/scatter factor (HGF/SF) display antitumor activity in animal models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2638505

5 June 2018

Activation of the Met receptor by cell attachment induces and sustains hepatocellular carcinomas in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2638505

5 June 2018

Medulloblastoma with extensive nodularity: a variant with favorable prognosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2638505

5 June 2018

Hepatocyte growth factor, a versatile signal for developing neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2638505

5 June 2018

A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice

1 reference

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5 June 2018

The mutationally activated Met receptor mediates motility and metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2638505

5 June 2018

Met and hepatocyte growth factor/scatter factor expression in human gliomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2638505

5 June 2018

Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2638505

5 June 2018

Scatter factor expression and regulation in human glial tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2638505

5 June 2018

Transgenic expression of tpr-met oncogene leads to development of mammary hyperplasia and tumors

1 reference

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Survival of infants with primitive neuroectodermal tumors or malignant ependymomas of the CNS treated with eight drugs in 1 day: a report from the Childrens Cancer Group.

1 reference

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A system for tissue-specific gene targeting: transgenic mice susceptible to subgroup A avian leukosis virus-based retroviral vectors

1 reference

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5 June 2018

Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product

1 reference

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5 June 2018

Apoptosis suppression by somatic cell transfer of Bcl-2 promotes Sonic hedgehog-dependent medulloblastoma formation in mice

1 reference

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18 August 2018

Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial

1 reference

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18 August 2018

N-myc can substitute for insulin-like growth factor signaling in a mouse model of sonic hedgehog-induced medulloblastoma

1 reference

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18 August 2018

Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice.

1 reference

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18 August 2018

The Sema domain of Met is necessary for receptor dimerization and activation

1 reference

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18 August 2018

Inhibition of intracerebral glioblastoma growth by local treatment with the scatter factor/hepatocyte growth factor-antagonist NK4.

1 reference

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18 August 2018

Induction of medulloblastomas in mice by sonic hedgehog, independent of Gli1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2638505

18 August 2018

In vivo targeting of SF/HGF and c-met expression via U1snRNA/ribozymes inhibits glioma growth and angiogenesis and promotes apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2638505

18 August 2018

Apoptosis, neuronal maturation, and neurotrophin expression within medulloblastoma nodules.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2638505

18 August 2018

Loss of p53 but not ARF accelerates medulloblastoma in mice heterozygous for patched.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2638505

18 August 2018

Hedgehog and patched in neural development and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2638505

18 August 2018

Inhibition of growth, invasion, and metastasis of human pancreatic carcinoma cells by NK4 in an orthotopic mouse model

1 reference

https://pubmed.ncbi.nlm.nih.gov/18829539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversion of human glioblastoma malignancy by U1 small nuclear RNA/ribozyme targeting of scatter factor/hepatocyte growth factor and c-met expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/18829539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoclonal antibody therapy of cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18829539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatocyte growth factor protects cultured rat cerebellar granule neurons from apoptosis via the phosphatidylinositol-3 kinase/Akt pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/18829539

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/0008-5472.CAN-08-1899

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

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