(Q41895629)

13 October 2017

Rational Design of Novel Pyridinol-Fused Ring Acetaminophen Analogues (English)

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13 October 2017

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1

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13 October 2017

8

John A Oates

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13 October 2017

10

Olivier Boutaud

1 reference

13 October 2017

Wei Liu

2

1 reference

13 October 2017

Huiyong Yin

3

1 reference

13 October 2017

Irene Zagol-Ikapitte

4

1 reference

13 October 2017

Taneem Amin

5

1 reference

13 October 2017

Byeong-Seon Jeong

6

1 reference

13 October 2017

L Jackson Roberts

7

1 reference

13 October 2017

Ned A Porter

9

1 reference

13 October 2017

1 August 2013

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ACS Medicinal Chemistry Letters

13 October 2017

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13 October 2017

4

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13 October 2017

8

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13 October 2017

710-714

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Acetaminophen inhibits cytochrome c redox cycling induced lipid peroxidation

13 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904457

Tyrosine-lipid peroxide adducts from radical termination: para coupling and intramolecular Diels-Alder cyclization.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904457

Structural Basis for Certain Naturally Occurring Bioflavonoids to Function as Reducing Co-Substrates of Cyclooxygenase I and II

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904457

Acetaminophen inhibits hemoprotein-catalyzed lipid peroxidation and attenuates rhabdomyolysis-induced renal failure

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904457

Pyridine and pyrimidine analogs of acetaminophen as inhibitors of lipid peroxidation and cyclooxygenase and lipoxygenase catalysis.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904457

Acetaminophen dosing of humans results in blood transcriptome and metabolome changes consistent with impaired oxidative phosphorylation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904457

Pharmacokinetics of acetaminophen-protein adducts in adults with acetaminophen overdose and acute liver failure

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904457

Acetaminophen-induced acute liver failure: results of a United States multicenter, prospective study

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904457

Acetaminophen and the U.S. Acute Liver Failure Study Group: lowering the risks of hepatic failure

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904457

Determinants of the cellular specificity of acetaminophen as an inhibitor of prostaglandin H(2) synthases.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904457

Antioxidant status in patients with uncomplicated insulin-dependent and non-insulin-dependent diabetes mellitus

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904457

N-acetyl-p-benzoquinone imine: a cytochrome P-450-mediated oxidation product of acetaminophen

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904457

Acetaminophen-induced hepatic necrosis. IV. Protective role of glutathione

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904457

Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904457

Prostaglandin synthase catalyzed metabolic activation of p-phenetidine and acetaminophen by microsomes isolated from rabbit and human kidney

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904457

Molecular mechanisms of the hepatotoxicity caused by acetaminophen

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904457

Preparation and investigation of vitamin B6-derived aminopyridinol antioxidants.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904457

Synthesis and structure-affinity relationships of new 4-(6-iodo-H-imidazo[1,2-a]pyridin-2-yl)-N-dimethylbenzeneamine derivatives as ligands for human beta-amyloid plaques.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904457

Mechanism of acetaminophen inhibition of cyclooxygenase isoforms

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904457

Revalidation of the in vitro alkaline elution/rat hepatocyte assay for DNA damage: improved criteria for assessment of cytotoxicity and genotoxicity and results for 81 compounds.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3904457

Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism

18 August 2018

1 reference

12 December 2020

Peroxidase-mediated formation of reactive metabolites of acetaminophen

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12 December 2020

Pyridoxine-derived bicyclic aminopyridinol antioxidants: synthesis and their antioxidant activities

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12 December 2020

Measurement of cytotoxicity by ATP-based luminescence assay in primary cell cultures and cell lines

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12 December 2020

The vitamin B6 derivatives structurally analogous to thiamine and their biological activity

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12 December 2020

A 7-year experience of severe acetaminophen-induced hepatotoxicity (1987-1993)

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12 December 2020

Identifiers

DOI

10.1021/ML4000904

1 reference

13 October 2017

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13 October 2017

PubMed publication ID

24482730

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