(Q41902175)

English

Neuronal NLRP1 inflammasome activation of Caspase-1 coordinately regulates inflammatory interleukin-1-beta production and axonal degeneration-associated Caspase-6 activation

scientific article published on 6 March 2015

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Neuronal NLRP1 inflammasome activation of Caspase-1 coordinately regulates inflammatory interleukin-1-beta production and axonal degeneration-associated Caspase-6 activation (English)

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

inflammasome complex

1 reference

based on heuristic

inferred from title

author name string

V Kaushal

1

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

R Dye

2

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

P Pakavathkumar

3

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

B Foveau

4

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

J Flores

5

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

B Hyman

6

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

B Ghetti

7

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

B H Koller

8

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

A C LeBlanc

9

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

language of work or name

0 references

publication date

6 March 2015

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Cell Death & Differentiation

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

22

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

10

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

1676-1686

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4563782/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

https://scigraph.springernature.com/pub.10.1038/cdd.2015.16

0 references

Amyloid-β induces NLRP1-dependent neuronal pyroptosis in models of Alzheimer's disease.

1 reference

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5 June 2018

Caspase-6 activity in the CA1 region of the hippocampus induces age-dependent memory impairment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563782

5 June 2018

Inflammasomes in the CNS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563782

5 June 2018

Pyroptotic neuronal cell death mediated by the AIM2 inflammasome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563782

5 June 2018

Inflammasome induction in Rasmussen's encephalitis: cortical and associated white matter pathogenesis

1 reference

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5 June 2018

Involvement of the spinal NALP1 inflammasome in neuropathic pain and aspirin-triggered-15-epi-lipoxin A4 induced analgesia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563782

5 June 2018

Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563782

5 June 2018

Cutting edge: the NLRP3 inflammasome links complement-mediated inflammation and IL-1β release.

1 reference

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5 June 2018

Identification of a novel endoplasmic reticulum stress response element regulated by XBP1.

1 reference

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5 June 2018

Distinct pathways mediate axon degeneration during apoptosis and axon-specific pruning

1 reference

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Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease

1 reference

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5 June 2018

Caspase-6 activity predicts lower episodic memory ability in aged individuals

1 reference

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5 June 2018

NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice

1 reference

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5 June 2018

A caspase cascade regulating developmental axon degeneration

1 reference

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Progress report on new antiepileptic drugs: a summary of the Eleventh Eilat Conference (EILAT XI)

1 reference

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5 June 2018

Targeting interleukin-1β in CAPS (cryopyrin-associated periodic) syndromes: what did we learn?

1 reference

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5 June 2018

Genome-wide association study of Alzheimer's disease

1 reference

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5 June 2018

Inflammasome-IL-1β Signaling Mediates Ethanol Inhibition of Hippocampal Neurogenesis

1 reference

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5 June 2018

Overlapping profiles of Aβ peptides in the Alzheimer's disease and pathological aging brains.

1 reference

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5 June 2018

The NALP3 inflammasome is involved in neurotoxic prion peptide-induced microglial activation

1 reference

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5 June 2018

Aspirin, steroidal and non-steroidal anti-inflammatory drugs for the treatment of Alzheimer's disease

1 reference

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5 June 2018

Rescue from excitotoxicity and axonal degeneration accompanied by age-dependent behavioral and neuroanatomical alterations in caspase-6-deficient mice

1 reference

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5 June 2018

Heightened inflammasome activation is linked to age-related cognitive impairment in Fischer 344 rats

1 reference

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5 June 2018

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

1 reference

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5 June 2018

Familial amyloid precursor protein mutants cause caspase-6-dependent but amyloid β-peptide-independent neuronal degeneration in primary human neuron cultures

1 reference

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5 June 2018

Epidemiology of Alzheimer disease

1 reference

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5 June 2018

Alternatively Spliced Caspase-6B Isoform Inhibits the Activation of Caspase-6A

1 reference

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5 June 2018

The inflammasomes

1 reference

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5 June 2018

Inflammasomes: too big to miss

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563782

5 June 2018

Caspase-6 activation in familial alzheimer disease brains carrying amyloid precursor protein or presenilin i or presenilin II mutations

1 reference

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5 June 2018

The pannexin 1 channel activates the inflammasome in neurons and astrocytes

1 reference

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5 June 2018

Therapeutic neutralization of the NLRP1 inflammasome reduces the innate immune response and improves histopathology after traumatic brain injury

1 reference

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APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

1 reference

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5 June 2018

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563782

5 June 2018

The NALP3 inflammasome is involved in the innate immune response to amyloid-beta

1 reference

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A molecular platform in neurons regulates inflammation after spinal cord injury

1 reference

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5 June 2018

The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective

1 reference

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Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration

1 reference

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5 June 2018

Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response

1 reference

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Inflammatory caspases and inflammasomes: master switches of inflammation

1 reference

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5 June 2018

Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry

1 reference

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Active caspase-6 and caspase-6-cleaved tau in neuropil threads, neuritic plaques, and neurofibrillary tangles of Alzheimer's disease

1 reference

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5 June 2018

Expression of NALP1 in cerebellar granule neurons stimulates apoptosis

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563782

5 June 2018

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30 September 2018

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

1 reference

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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5 June 2018

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

1 reference

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Microglial activation of the NLRP3 inflammasome by the priming signals derived from macrophages infected with mycobacteria

1 reference

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NALP1/NLRP1 genetic variants are associated with Alzheimer disease.

1 reference

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18 August 2018

Inhibition of the inflammasome complex reduces the inflammatory response after thromboembolic stroke in mice.

1 reference

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18 August 2018

Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer's disease

1 reference

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18 August 2018

Caspase-1 activation of caspase-6 in human apoptotic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/25744023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid precursor protein metabolism in primary cell cultures of neurons, astrocytes, and microglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/25744023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induced expression of death domain genes NALP1 and NALP5 following neuronal injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/25744023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased production of 4 kDa amyloid beta peptide in serum deprived human primary neuron cultures: possible involvement of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25744023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/CDD.2015.16

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

ResearchGate publication ID

0 references

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