(Q30512263)

English

Rescue from excitotoxicity and axonal degeneration accompanied by age-dependent behavioral and neuroanatomical alterations in caspase-6-deficient mice

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Rescue from excitotoxicity and axonal degeneration accompanied by age-dependent behavioral and neuroanatomical alterations in caspase-6-deficient mice (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

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inferred from title

Michael R. Hayden

21

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Michael R Hayden

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Europe PubMed Central

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10 August 2017

Freda D. Miller

18

object named as

Freda D Miller

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10 August 2017

author name string

Valeria Uribe

1

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10 August 2017

Bibiana K Y Wong

2

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10 August 2017

Rona K Graham

3

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10 August 2017

Corey L Cusack

4

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10 August 2017

Niels H Skotte

5

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10 August 2017

Mahmoud A Pouladi

6

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10 August 2017

Yuanyun Xie

7

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10 August 2017

Konstantin Feinberg

8

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10 August 2017

Yimiao Ou

9

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10 August 2017

Yingbin Ouyang

10

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10 August 2017

Yu Deng

11

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10 August 2017

Sonia Franciosi

12

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10 August 2017

Nagat Bissada

13

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10 August 2017

Amanda Spreeuw

14

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10 August 2017

Weining Zhang

15

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10 August 2017

Dagmar E Ehrnhoefer

16

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10 August 2017

Kuljeet Vaid

17

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10 August 2017

Mohanish Deshmukh

19

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David Howland

20

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publication date

18 January 2012

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Human Molecular Genetics

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10 August 2017

21

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10 August 2017

9

1 reference

Europe PubMed Central

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10 August 2017

1954-1967

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10 August 2017

Intranasal delivery of caspase-9 inhibitor reduces caspase-6-dependent axon/neuron loss and improves neurological function after stroke

1 reference

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28 July 2018

Transgenic mice expressing caspase-6-derived N-terminal fragments of mutant huntingtin develop neurologic abnormalities with predominant cytoplasmic inclusion pathology composed largely of a smaller proteolytic derivative

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28 July 2018

Natural history of disease in the YAC128 mouse reveals a discrete signature of pathology in Huntington disease

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28 July 2018

Familial amyloid precursor protein mutants cause caspase-6-dependent but amyloid β-peptide-independent neuronal degeneration in primary human neuron cultures

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28 July 2018

Regulation of caspases in the nervous system implications for functions in health and disease

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28 July 2018

Characterisation of a new regulator of BDNF signalling, Sprouty3, involved in axonal morphogenesis in vivo

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28 July 2018

Phosphorylation of huntingtin at Ser421 in YAC128 neurons is associated with protection of YAC128 neurons from NMDA-mediated excitotoxicity and is modulated by PP1 and PP2A.

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28 July 2018

Importance of the Caspase Cleavage Site in Amyloid-β Protein Precursor

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28 July 2018

Neuroprotection signaling pathway of nerve growth factor and brain-derived neurotrophic factor against staurosporine induced apoptosis in hippocampal H19-7/IGF-IR [corrected].

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28 July 2018

alpha-Synuclein- and MPTP-generated rodent models of Parkinson's disease and the study of extracellular striatal dopamine dynamics: a microdialysis approach.

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28 July 2018

Caspase-3 activation via mitochondria is required for long-term depression and AMPA receptor internalization.

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28 July 2018

Loss of tau elicits axonal degeneration in a mouse model of Alzheimer's disease

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28 July 2018

Striatal and white matter predictors of estimated diagnosis for Huntington disease

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28 July 2018

Early increase in extrasynaptic NMDA receptor signaling and expression contributes to phenotype onset in Huntington's disease mice

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28 July 2018

Global deprivation of brain-derived neurotrophic factor in the CNS reveals an area-specific requirement for dendritic growth

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28 July 2018

Many neuronal and behavioral impairments in transgenic mouse models of Alzheimer's disease are independent of caspase cleavage of the amyloid precursor protein

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28 July 2018

Caspase-6 activation in familial alzheimer disease brains carrying amyloid precursor protein or presenilin i or presenilin II mutations

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28 July 2018

Reversal of learning deficits in hAPP transgenic mice carrying a mutation at Asp664: a role for early experience

1 reference

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28 July 2018

APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

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28 July 2018

Kihi-to, a herbal traditional medicine, improves Abeta(25-35)-induced memory impairment and losses of neurites and synapses

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28 July 2018

Death receptors and caspases but not mitochondria are activated in the GDNF- or BDNF-deprived dopaminergic neurons.

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28 July 2018

Long-term prevention of Alzheimer's disease-like behavioral deficits in PDAPP mice carrying a mutation in Asp664.

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28 July 2018

C-terminal cleavage of the amyloid-beta protein precursor at Asp664: a switch associated with Alzheimer's disease

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28 July 2018

BDNF is essential to promote persistence of long-term memory storage

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28 July 2018

BDNF and memory formation and storage.

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28 July 2018

Activation of caspase-6 in aging and mild cognitive impairment

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28 July 2018

Learning-memory deficit with aging in APP transgenic mice of Alzheimer's disease and intervention by using tetrahydroxystilbene glucoside

1 reference

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28 July 2018

Adaptive roles of programmed cell death during nervous system development

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28 July 2018

Reversal of Alzheimer's-like pathology and behavior in human APP transgenic mice by mutation of Asp664.

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28 July 2018

Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress

1 reference

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28 July 2018

Proteolytic cleavage of polyglutamine-expanded ataxin-3 is critical for aggregation and sequestration of non-expanded ataxin-3.

1 reference

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28 July 2018

Axon retraction and degeneration in development and disease

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28 July 2018

Prospects for caspase inhibitors.

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28 July 2018

Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis

1 reference

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28 July 2018

Brain-derived neurotrophic factor is required for the maintenance of cortical dendrites

1 reference

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28 July 2018

Proteolytic cleavage and cellular toxicity of the human alpha1A calcium channel in spinocerebellar ataxia type 6.

1 reference

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28 July 2018

Many cuts to ruin: a comprehensive update of caspase substrates

1 reference

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28 July 2018

Expression and differential processing of caspases 6 and 7 in relation to specific epileptiform EEG patterns following limbic seizures

1 reference

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28 July 2018

Caspases on the brain

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28 July 2018

Axonal self-destruction and neurodegeneration

1 reference

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28 July 2018

The effect of excitotoxic lesions centered on the hippocampus or perirhinal cortex in object recognition and spatial memory tasks

1 reference

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28 July 2018

Recognition memory: what are the roles of the perirhinal cortex and hippocampus?

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28 July 2018

Neurotrophins as synaptic modulators

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28 July 2018

The effects of aging on gene expression in the hypothalamus and cortex of mice

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28 July 2018

Caspase knockouts: matters of life and death.

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28 July 2018

Caspase structure, proteolytic substrates, and function during apoptotic cell death

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28 July 2018

Enhanced sensitivity to N-methyl-D-aspartate receptor activation in transgenic and knockin mouse models of Huntington's disease

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28 July 2018

Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation

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28 July 2018

Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models

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28 July 2018

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

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28 July 2018

Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.

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28 July 2018

Differential requirement for caspase 9 in apoptotic pathways in vivo.

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28 July 2018

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

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28 July 2018

Extensive cytotoxic lesions involving both the rhinal cortices and area TE impair recognition but spare spatial alternation in the rat.

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28 July 2018

Programmed cell death and the control of cell survival: lessons from the nervous system

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28 July 2018

Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family

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28 July 2018

Magnetic resonance imaging (MRI) and model-free estimates of brain volume determined using the Cavalieri principle

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28 July 2018

Mechanisms and Functions of Cell Death

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28 July 2018

Apoptosis: Mechanisms and Roles in Pathology

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28 July 2018

Early changes in white matter pathways of the sensorimotor cortex in premanifest Huntington's disease

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26 November 2018

Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease.

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26 November 2018

Identification and evaluation of small molecule pan-caspase inhibitors in Huntington's disease models

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26 November 2018

Phenylbutyrate rescues dendritic spine loss associated with memory deficits in a mouse model of Alzheimer disease

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26 November 2018

Cleavage at the 586 amino acid caspase-6 site in mutant huntingtin influences caspase-6 activation in vivo.

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26 November 2018

Motor deficits, neuron loss, and reduced anxiety coinciding with axonal degeneration and intraneuronal Aβ aggregation in the 5XFAD mouse model of Alzheimer's disease.

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26 November 2018

p75NTR-dependent, myelin-mediated axonal degeneration regulates neural connectivity in the adult brain

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26 November 2018

Altered white matter microstructure in the corpus callosum in Huntington's disease: implications for cortical "disconnection".

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26 November 2018

Spermine improves recognition memory deficit in a rodent model of Huntington's disease

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26 November 2018

Prevention of depressive behaviour in the YAC128 mouse model of Huntington disease by mutation at residue 586 of huntingtin

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26 November 2018

Regional white matter volume differences in nondemented aging and Alzheimer's disease

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26 November 2018

Neuroprotection by NGF and BDNF against neurotoxin-exerted apoptotic death in neural stem cells are mediated through Trk receptors, activating PI3-kinase and MAPK pathways

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26 November 2018

Developmental axon pruning mediated by BDNF-p75NTR-dependent axon degeneration

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26 November 2018

Protein synthesis and neurotrophin-dependent structural plasticity of single dendritic spines.

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26 November 2018

Impaired GABAergic inhibition in the visual cortex of brain-derived neurotrophic factor heterozygous knockout mice.

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26 November 2018

Signal transduction in Alzheimer disease: p21-activated kinase signaling requires C-terminal cleavage of APP at Asp664.

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26 November 2018

Sprouty2 inhibits BDNF-induced signaling and modulates neuronal differentiation and survival.

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26 November 2018

Deficits in synaptic transmission and learning in amyloid precursor protein (APP) transgenic mice require C-terminal cleavage of APP.

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26 November 2018

Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin

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26 November 2018

Levels of mutant huntingtin influence the phenotypic severity of Huntington disease in YAC128 mouse models

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26 November 2018

Cognitive dysfunction precedes neuropathology and motor abnormalities in the YAC128 mouse model of Huntington's disease.

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26 November 2018

Caspase 6 expression in the rat hippocampus during epileptogenesis and epilepsy

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26 November 2018

Caspase-7 expanded function and intrinsic expression level underlies strain-specific brain phenotype of caspase-3-null mice.

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26 November 2018

Potentiation of NMDA receptor-mediated excitotoxicity linked with intrinsic apoptotic pathway in YAC transgenic mouse model of Huntington's disease

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26 November 2018

Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315204

26 November 2018

Brain-derived neurotrophic factor in the ventral midbrain-nucleus accumbens pathway: a role in depression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315204

26 November 2018

Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315204

26 November 2018

Caspase cleavage of mutant huntingtin precedes neurodegeneration in Huntington's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315204

26 November 2018

Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315204

26 November 2018

Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315204

26 November 2018

Caspase activity plays an essential role in long-term memory.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315204

26 November 2018

Differential neuronal responsiveness in primate perirhinal cortex and hippocampal formation during performance of a conditional visual discrimination task.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315204

26 November 2018

Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315204

26 November 2018

All's well that ends dead

1 reference

https://pubmed.ncbi.nlm.nih.gov/22262731

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/22262731

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of muscle spindle innervation by neurotrophin-3 following nerve injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/22262731

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-1 activation of caspase-6 in human apoptotic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/22262731

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A stereological study of MRI and the Cavalieri principle combined for diagnosis and monitoring of brain tumor volume

1 reference

https://pubmed.ncbi.nlm.nih.gov/22262731

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/HMG/DDS005

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

ResearchGate publication ID

0 references

Sitelinks

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