(Q41911100)

English

Functional coupling of last-intron splicing and 3'-end processing to transcription in vitro: the poly(A) signal couples to splicing before committing to cleavage

scientific article published on 29 October 2007

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scholarly article

1 reference

Europe PubMed Central

14 October 2017

Functional coupling of last-intron splicing and 3'-end processing to transcription in vitro: the poly(A) signal couples to splicing before committing to cleavage (English)

1 reference

Europe PubMed Central

14 October 2017

author name string

Frank Rigo

1

1 reference

Europe PubMed Central

14 October 2017

Harold G Martinson

2

1 reference

Europe PubMed Central

14 October 2017

language of work or name

0 references

publication date

29 October 2007

1 reference

Europe PubMed Central

14 October 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

14 October 2017

28

1 reference

Europe PubMed Central

14 October 2017

849-862

1 reference

Europe PubMed Central

14 October 2017

2

1 reference

Europe PubMed Central

14 October 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2223410/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Concurrent splicing and transcription are not sufficient to enhance splicing efficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Transcription termination factor Pcf11 limits the processivity of Pol II on an HIV provirus to repress gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

SR proteins function in coupling RNAP II transcription to pre-mRNA splicing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

The poly(A)-dependent transcriptional pause is mediated by CPSF acting on the body of the polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

RNA polymerase II C-terminal domain mediates regulation of alternative splicing by SRp20.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

An interaction between U2AF 65 and CF I(m) links the splicing and 3' end processing machineries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

The conserved AAUAAA hexamer of the poly(A) signal can act alone to trigger a stable decrease in RNA polymerase II transcription velocity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Functional coupling of RNAP II transcription to spliceosome assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Linking splicing to Pol II transcription stabilizes pre-mRNAs and influences splicing patterns

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Exon tethering in transcription by RNA polymerase II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

RNA editing and alternative splicing: the importance of co-transcriptional coordination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Ribozyme cleavage reveals connections between mRNA release from the site of transcription and pre-mRNA processing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

The architecture of pre-mRNAs affects mechanisms of splice-site pairing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Role for PSF in mediating transcriptional activator-dependent stimulation of pre-mRNA processing in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

A subset of nuclear receptor coregulators act as coupling proteins during synthesis and maturation of RNA transcripts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Analysis of a noncanonical poly(A) site reveals a tripartite mechanism for vertebrate poly(A) site recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

A simple answer for a splicing conundrum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

The C-terminal domain of RNA polymerase II functions as a phosphorylation-dependent splicing activator in a heterologous protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Multiple links between transcription and splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Newly Initiated RNA encounters a factor involved in splicing immediately upon emerging from within RNA polymerase II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Recognition of RNA polymerase II carboxy-terminal domain by 3'-RNA-processing factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

New perspectives on connecting messenger RNA 3' end formation to transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Functional interactions of RNA-capping enzyme with factors that positively and negatively regulate promoter escape by RNA polymerase II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

The link between mRNA processing and transcription: communication works both ways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

A mechanism for the regulation of pre-mRNA 3' processing by human cleavage factor Im

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

The Tat/TAR-dependent phosphorylation of RNA polymerase II C-terminal domain stimulates cotranscriptional capping of HIV-1 mRNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Strange bedfellows: polyadenylation factors at the promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Mechanisms of alternative pre-messenger RNA splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Promoter proximal splice sites enhance transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Tat stimulates cotranscriptional capping of HIV mRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

An extensive network of coupling among gene expression machines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Requirements of the RNA polymerase II C-terminal domain for reconstituting pre-mRNA 3' cleavage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Stimulatory effect of splicing factors on transcriptional elongation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

A human RNA polymerase II-containing complex associated with factors necessary for spliceosome assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Mechanism of poly(A) signal transduction to RNA polymerase II in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Capping, splicing, and 3' processing are independently stimulated by RNA polymerase II: different functions for different segments of the CTD

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

The 3'-end-processing factor CPSF is required for the splicing of single-intron pre-mRNAs in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Human pre-mRNA cleavage factor II(m) contains homologs of yeast proteins and bridges two other cleavage factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Participation of the C-terminal domain of RNA polymerase II in exon definition during pre-mRNA splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Coupled in vitro synthesis and splicing of RNA polymerase II transcripts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

The carboxyl terminus of vertebrate poly(A) polymerase interacts with U2AF 65 to couple 3'-end processing and splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Properties of cloned and expressed human RNase H1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Assembly of the cleavage and polyadenylation apparatus requires about 10 seconds in vivo and is faster for strong than for weak poly(A) sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Utilization of splicing elements and polyadenylation signal elements in the coupling of polyadenylation and last-intron removal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Specific transcriptional pausing activates polyadenylation in a coupled in vitro system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Formation of mRNA 3' ends in eukaryotes: mechanism, regulation, and interrelationships with other steps in mRNA synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Phosphorylated RNA polymerase II stimulates pre-mRNA splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

RNA polymerase II is an essential mRNA polyadenylation factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Human pre-mRNA cleavage factor Im is related to spliceosomal SR proteins and can be reconstituted in vitro from recombinant subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Efficient 3'-end formation of human beta-globin mRNA in vivo requires sequences within the last intron but occurs independently of the splicing reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Participation of the nuclear cap binding complex in pre-mRNA 3' processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Transcription factor TFIID recruits factor CPSF for formation of 3' end of mRNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

The C-terminal domain of RNA polymerase II couples mRNA processing to transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

A hyperphosphorylated form of the large subunit of RNA polymerase II is associated with splicing complexes and the nuclear matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Purification and characterization of human cleavage factor Im involved in the 3' end processing of messenger RNA precursors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Exon recognition in vertebrate splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

The 160-kD subunit of human cleavage-polyadenylation specificity factor coordinates pre-mRNA 3'-end formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

A single-base change at a splice site in a beta 0-thalassemic gene causes abnormal RNA splicing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

In vitro splicing pathways of pre-mRNAs containing multiple intervening sequences?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

An ordered pathway of assembly of components required for polyadenylation site recognition and processing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Effect of 5' splice site mutations on splicing of the preceding intron

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

5 June 2018

Direct interactions between subunits of CPSF and the U2 snRNP contribute to the coupling of pre-mRNA 3' end processing and splicing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

18 August 2018

Pcf11 is a termination factor in Drosophila that dismantles the elongation complex by bridging the CTD of RNA polymerase II to the nascent transcript

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

18 August 2018

The RNA tether from the poly(A) signal to the polymerase mediates coupling of transcription to cleavage and polyadenylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

18 August 2018

In vitro coupled transcription splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

18 August 2018

Functional coupling of cleavage and polyadenylation with transcription of mRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

18 August 2018

Functional coupling of capping and transcription of mRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

18 August 2018

A nuclear cap-binding complex facilitates association of U1 snRNP with the cap-proximal 5' splice site.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223410

18 August 2018

Normal and mutant human β-globin pre-mRNAs are faithfully and efficiently spliced in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/17967872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro transcription from the adenovirus 2 major late promoter utilizing templates truncated at promoter-proximal sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/17967872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro polyadenylation is stimulated by the presence of an upstream intron

1 reference

https://pubmed.ncbi.nlm.nih.gov/17967872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coupled transcription-polyadenylation in a cell-free system

1 reference

https://pubmed.ncbi.nlm.nih.gov/17967872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation of the AAUAAA polyadenylation signal depresses in vitro splicing of proximal but not distal introns

1 reference

https://pubmed.ncbi.nlm.nih.gov/17967872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spi-1/PU.1 oncoprotein affects splicing decisions in a promoter binding-dependent manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/17967872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cotranscriptional coupling of splicing factor recruitment and precursor messenger RNA splicing in mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17967872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The C-terminal domains of vertebrate CstF-64 and its yeast orthologue Rna15 form a new structure critical for mRNA 3'-end processing

1 reference

https://pubmed.ncbi.nlm.nih.gov/17967872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chromatin, transcript elongation and alternative splicing

1 reference

https://pubmed.ncbi.nlm.nih.gov/17967872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Terminal exon definition occurs cotranscriptionally and promotes termination of RNA polymerase II

1 reference

https://pubmed.ncbi.nlm.nih.gov/17967872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.01410-07

1 reference

Europe PubMed Central

14 October 2017

1 reference

Europe PubMed Central

14 October 2017

1 reference

Europe PubMed Central

14 October 2017

ResearchGate publication ID

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