(Q41938509)

English

Essential role of STAT1 in caspase-independent cell death of activated macrophages through the p38 mitogen-activated protein kinase/STAT1/reactive oxygen species pathway

scientific article published on August 2005

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Essential role of STAT1 in caspase-independent cell death of activated macrophages through the p38 mitogen-activated protein kinase/STAT1/reactive oxygen species pathway (English)

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

reactive oxygen species

1 reference

based on heuristic

inferred from title

author name string

Hun Sik Kim

1

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Myung-Shik Lee

2

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

language of work or name

0 references

publication date

1 August 2005

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

25

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

15

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

6821-6833

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases

1 reference

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Signaling of apoptosis through TLRs critically involves toll/IL-1 receptor domain-containing adapter inducing IFN-beta, but not MyD88, in bacteria-infected murine macrophages

1 reference

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5 June 2018

Essential roles of receptor-interacting protein and TRAF2 in oxidative stress-induced cell death

1 reference

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5 June 2018

ERK activation promotes neuronal degeneration predominantly through plasma membrane damage and independently of caspase-3.

1 reference

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Necrosis-like cell death induced by bacteria in mouse macrophages

1 reference

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The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4.

1 reference

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The up-regulation of human caspase-8 by interferon-gamma in breast tumor cells requires the induction and action of the transcription factor interferon regulatory factor-1.

1 reference

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5 June 2018

STAT1-induced apoptosis is mediated by caspases 2, 3, and 7.

1 reference

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STAT-1α and IFN-γ as Modulators of TNF-α Signaling in Macrophages: Regulation and Functional Implications of the TNF Receptor 1:STAT-1α Complex

1 reference

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Regulation of necrosis of H9c2 myogenic cells upon transient energy deprivation. Rapid deenergization of mitochondria precedes necrosis and is controlled by reactive oxygen species, stress kinase JNK, HSP72 and ARC.

1 reference

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Orphan nuclear receptor Nur77 is involved in caspase-independent macrophage cell death

1 reference

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5 June 2018

Toll-like receptors 2 and 4 activate STAT1 serine phosphorylation by distinct mechanisms in macrophages

1 reference

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The immunopathogenesis of sepsis

1 reference

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5 June 2018

Specific involvement of caspases in the differentiation of monocytes into macrophages

1 reference

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5 June 2018

Interferon gamma is required for activation-induced death of T lymphocytes

1 reference

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5 June 2018

The C-terminal activation domain of the STAT-1 transcription factor is necessary and sufficient for stress-induced apoptosis

1 reference

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Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition

1 reference

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Implication of the small GTPase Rac1 in the generation of reactive oxygen species in response to beta-amyloid in C6 astroglioma cells

1 reference

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5 June 2018

TLR4, but not TLR2, mediates IFN-beta-induced STAT1alpha/beta-dependent gene expression in macrophages.

1 reference

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5 June 2018

NF-kappaB at the crossroads of life and death

1 reference

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5 June 2018

Cooperation of STAT-1 and IRF-1 in interferon-gamma-induced transcription of the gp91(phox) gene

1 reference

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5 June 2018

Enhanced ROS production in oncogenically transformed cells potentiates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase activation and sensitization to genotoxic stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190352

5 June 2018

Four deaths and a funeral: from caspases to alternative mechanisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1190352

5 June 2018

Toll-like receptors: critical proteins linking innate and acquired immunity

1 reference

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5 June 2018

Induction of apoptosis and Fas receptor/Fas ligand expression by ischemia/reperfusion in cardiac myocytes requires serine 727 of the STAT-1 transcription factor but not tyrosine 701.

1 reference

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Interferon gamma (IFNgamma ) and tumor necrosis factor alpha synergism in ME-180 cervical cancer cell apoptosis and necrosis. IFNgamma inhibits cytoprotective NF-kappa B through STAT1/IRF-1 pathways

1 reference

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IFN-gamma/TNF-alpha synergism as the final effector in autoimmune diabetes: a key role for STAT1/IFN regulatory factor-1 pathway in pancreatic beta cell death

1 reference

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Caspase activation is required for terminal erythroid differentiation

1 reference

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Necrotic death pathway in Fas receptor signaling

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Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

1 reference

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Toll-like receptors in the induction of the innate immune response

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IFN-beta induces serine phosphorylation of Stat-1 in Ewing's sarcoma cells and mediates apoptosis via induction of IRF-1 and activation of caspase-7

1 reference

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Induction of necrotic-like cell death by tumor necrosis factor alpha and caspase inhibitors: novel mechanism for killing virus-infected cells

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Stat1 as a component of tumor necrosis factor alpha receptor 1-TRADD signaling complex to inhibit NF-kappaB activation

1 reference

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More than one way to die: apoptosis, necrosis and reactive oxygen damage

1 reference

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Caspase activation is required for T cell proliferation

1 reference

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Early activation of caspases during T lymphocyte stimulation results in selective substrate cleavage in nonapoptotic cells

1 reference

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Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-gamma uses a different signaling pathway

1 reference

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p38 MAP kinase is required for STAT1 serine phosphorylation and transcriptional activation induced by interferons

1 reference

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Redox regulation of cellular signalling

1 reference

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Activation of the JAK-STAT pathway by reactive oxygen species.

1 reference

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Host tissue damage by phagocytes

1 reference

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STAT1 is inactivated by a caspase

1 reference

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Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases

1 reference

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Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis

1 reference

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Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

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Endotoxins and disease mechanisms

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Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis.

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Resistance to the cytotoxic effects of tumor necrosis factor alpha can be overcome by inhibition of a FADD/caspase-dependent signaling pathway

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Selective involvement of superoxide anion, but not downstream compounds hydrogen peroxide and peroxynitrite, in tumor necrosis factor-alpha-induced apoptosis of rat mesangial cells

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inferred from PubMed ID database lookup

A caspaselike activity is triggered by LPS and is required for survival of human dendritic cells

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Synovial tissue macrophage populations and articular damage in rheumatoid arthritis

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inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.25.15.6821-6833.2005

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

ResearchGate publication ID

0 references

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