(Q41942305)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25431548%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

De-regulation of gene expression and alternative splicing affects distinct cellular pathways in the aging hippocampus (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25431548%20AND%20SRC:MED&resulttype=core&format=json

alternative mRNA splicing, via spliceosome

23 February 2020

main subject

RNA sequencing

0 references

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25431548%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Eva Benito

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25431548%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Stefan Bonn

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25431548%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

author name string

Michael Gertig

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25431548%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Jonas Barth

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25431548%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Vincenzo Capece

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25431548%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Susanne Burkhardt

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25431548%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Andre Fischer

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25431548%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

language of work or name

1 reference

13 November 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25431548%20AND%20SRC:MED&resulttype=core&format=json

Frontiers in Cellular Neuroscience

23 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25431548%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25431548%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

page(s)

373

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25431548%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

23 February 2020

limma

object named as

Limma

2 references

22 June 2022

https://europepmc.org/article/PMC/4230043

based on heuristic

inferred from PubMed Central ID database lookup

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

DESeq2

object named as

DESeq2

1 reference

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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MALAT-1, a non protein-coding RNA is upregulated in the cerebellum, hippocampus and brain stem of human alcoholics

5 June 2018

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Whole transcriptome sequencing of the aging rat brain reveals dynamic RNA changes in the dark matter of the genome

5 June 2018

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Epidemiological, genetic and epigenetic aspects of the research on healthy ageing and longevity.

5 June 2018

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RNA-Seq analysis of frontal cortex and cerebellum from 5XFAD mice at early stage of disease pathology

5 June 2018

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5 June 2018

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5 June 2018

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A coding variant in CR1 interacts with APOE-ε4 to influence cognitive decline

5 June 2018

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5 June 2018

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5 June 2018

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The novel object recognition memory: neurobiology, test procedure, and its modifications

5 June 2018

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A hippocampal insulin-growth factor 2 pathway regulates the extinction of fear memories

5 June 2018

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Voluntary wheel running reverses age-induced changes in hippocampal gene expression

5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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5 June 2018

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Replication of CLU, CR1, and PICALM associations with alzheimer disease.

5 June 2018

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Altered histone acetylation is associated with age-dependent memory impairment in mice.

5 June 2018

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5 June 2018

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Neural mechanisms of ageing and cognitive decline

5 June 2018

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Object recognition memory and the rodent hippocampus

5 June 2018

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From contextual fear to a dynamic view of memory systems

5 June 2018

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Expression of complement system components during aging and amyloid deposition in APP transgenic mice

5 June 2018

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Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

5 June 2018

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Paraspeckles: nuclear bodies built on long noncoding RNA

5 June 2018

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5 June 2018

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Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

5 June 2018

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Gene expression changes in the course of normal brain aging are sexually dimorphic

5 June 2018

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Evolution of the aging brain transcriptome and synaptic regulation

5 June 2018

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Complement C3 deficiency leads to accelerated amyloid beta plaque deposition and neurodegeneration and modulation of the microglia/macrophage phenotype in amyloid precursor protein transgenic mice

5 June 2018

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AGEMAP: a gene expression database for aging in mice

5 June 2018

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Gene expression atlas of the mouse central nervous system: impact and interactions of age, energy intake and gender

5 June 2018

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Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database

5 June 2018

1 reference

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Nucleocytosolic acetyl-coenzyme a synthetase is required for histone acetylation and global transcription

5 June 2018

1 reference

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Linear models and empirical bayes methods for assessing differential expression in microarray experiments

5 June 2018

1 reference

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

5 June 2018

1 reference

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Exercise enhances learning and hippocampal neurogenesis in aged mice.

5 June 2018

1 reference

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Can flies shed light on our own age-related memory impairment?

5 June 2018

1 reference

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Using animal models to determine the significance of complement activation in Alzheimer's disease

5 June 2018

1 reference

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Bioconductor: open software development for computational biology and bioinformatics

5 June 2018

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Gene regulation and DNA damage in the ageing human brain

5 June 2018

1 reference

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Altered hippocampal transcript profile accompanies an age-related spatial memory deficit in mice

5 June 2018

1 reference

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Central nervous system-targeted complement inhibition mediates neuroprotection after closed head injury in transgenic mice

5 June 2018

1 reference

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PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

5 June 2018

1 reference

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Variance stabilization applied to microarray data calibration and to the quantification of differential expression

5 June 2018

1 reference

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Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice

5 June 2018

1 reference

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Genome-wide transcript profiles in aging and calorically restricted Drosophila melanogaster

5 June 2018

1 reference

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What counts in brain aging? Design-based stereological analysis of cell number

5 June 2018

1 reference

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Running enhances neurogenesis, learning, and long-term potentiation in mice

5 June 2018

2 references

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5 June 2018

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Neuronal expression of mRNAs for complement proteins of the classical pathway in Alzheimer brain.

21 January 2018

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Neurons express proteins of the classical complement pathway in Alzheimer disease.

5 June 2018

1 reference

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Murine models of brain aging and age-related neurodegenerative diseases

5 June 2018

1 reference

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RNA and Protein Metabolism in the Aging Brain

5 June 2018

1 reference

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IKKβ deficiency in myeloid cells ameliorates Alzheimer's disease-related symptoms and pathology

5 June 2018

1 reference

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Blockage of CR1 prevents activation of rodent microglia

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4230043

Histone-methyltransferase MLL2 (KMT2B) is required for memory formation in mice.

18 August 2018

1 reference

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Genetic association of CR1 with Alzheimer's disease: a tentative disease mechanism.

18 August 2018

1 reference

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The impact of aging on the brain--risk, resilience and repair.

18 August 2018

1 reference

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18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4230043

Modulation of anxiety behavior by intranasally administered vaccinia virus complement control protein and curcumin in a mouse model of Alzheimer's disease

18 August 2018

1 reference

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Pscan: finding over-represented transcription factor binding site motifs in sequences from co-regulated or co-expressed genes

18 August 2018

1 reference

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Hippocampal gene expression changes during age-related cognitive decline.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4230043

Intracranial administration of vaccinia virus complement control protein in Mo/Hu APPswe PS1dE9 transgenic mice at an early age shows enhanced performance at a later age using a cheese board maze test

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4230043

Early detection of memory deficits and memory improvement with vaccinia virus complement control protein in an Alzheimer's disease model

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4230043

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4230043

Pharmacological complement inhibition at the C3 convertase level promotes neuronal survival, neuroprotective intracerebral gene expression, and neurological outcome after traumatic brain injury.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4230043

Use of within-array replicate spots for assessing differential expression in microarray experiments.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4230043

Absence of C1q leads to less neuropathology in transgenic mouse models of Alzheimer's disease.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4230043

Gene Microarrays in Hippocampal Aging: Statistical Profiling Identifies Novel Processes Correlated with Cognitive Impairment

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4230043

Expression of complement messenger RNAs and proteins by human oligodendroglial cells

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4230043

Astrocyte changes in aging cerebral cortex and hippocampus: a quantitative immunohistochemical study

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4230043

Prevalence of age-associated memory impairment in a randomly selected population from eastern Finland

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4230043

Missense variants in CR1 are associated with increased risk of Alzheimer' disease in Han Chinese

18 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00373

Transcription factors in autoimmune diseases

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25431548

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Qualitative and quantitative glial changes in the hippocampus of aged rats

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25431548

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3389/FNCEL.2014.00373

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25431548%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25431548%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

PubMed publication ID

25431548

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25431548%20AND%20SRC:MED&resulttype=core&format=json