(Q41952334)

English

Aldosterone stimulates elastogenesis in cardiac fibroblasts via mineralocorticoid receptor-independent action involving the consecutive activation of Galpha13, c-Src, the insulin-like growth factor-I receptor, and phosphatidylinositol 3-kinase/Akt

scientific article published on 16 April 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Aldosterone stimulates elastogenesis in cardiac fibroblasts via mineralocorticoid receptor-independent action involving the consecutive activation of Galpha13, c-Src, the insulin-like growth factor-I receptor, and phosphatidylinositol 3-kinase/Akt (English)

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

author name string

Severa Bunda

1

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Yanting Wang

2

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Thomas F Mitts

3

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Peter Liu

4

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Sara Arab

5

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Majid Arabkhari

6

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Aleksander Hinek

7

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

language of work or name

0 references

publication date

16 April 2009

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

number of pages

15

1 reference

based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

284

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

24

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

16633-16647

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Association of the membrane estrogen receptor, GPR30, with breast tumor metastasis and transactivation of the epidermal growth factor receptor

1 reference

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Classic versus non-classic receptors for nongenomic mineralocorticoid responses: emerging evidence

1 reference

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5 June 2018

Aldosterone induces elastin production in cardiac fibroblasts through activation of insulin-like growth factor-I receptors in a mineralocorticoid receptor-independent manner

1 reference

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Galpha12/13-mediated up-regulation of TRPC6 negatively regulates endothelin-1-induced cardiac myofibroblast formation and collagen synthesis through nuclear factor of activated T cells activation.

1 reference

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Rapid stimulation of tyrosine phosphorylation signals downstream of G-protein-coupled receptors for thromboxane A2 in human platelets.

1 reference

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Targeted knockdown of G protein subunits selectively prevents receptor-mediated modulation of effectors and reveals complex changes in non-targeted signaling proteins

1 reference

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Aldosterone and the kidney: rapid regulation of renal microcirculation

1 reference

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Nongenomic actions of aldosterone: physiological or pathophysiological role?

1 reference

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Aldosterone receptor antagonism in heart failure

1 reference

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The new biology of aldosterone

1 reference

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Cardioprotective stress response in the human fetal heart

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Src kinase regulation by phosphorylation and dephosphorylation

1 reference

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Early nongenomic events in aldosterone action in renal collecting duct cells: PKCalpha activation, mineralocorticoid receptor phosphorylation, and cross-talk with the genomic response.

1 reference

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5 June 2018

Gα12 and Gα13 as key regulatory mediator in signal transduction

1 reference

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The biochemistry and physiology of metallic fluoride: action, mechanism, and implications

1 reference

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G alpha 13-mediated transformation and apoptosis are permissively dependent on basal ERK activity

1 reference

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5 June 2018

Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction

1 reference

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1 reference

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N-terminal short sequences of alpha subunits of the G12 family determine selective coupling to receptors.

1 reference

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5 June 2018

Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes

1 reference

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Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis

1 reference

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5 June 2018

Rho/ROCK pathway contributes to the activation of extracellular signal-regulated kinase/GATA-4 during myocardial cell hypertrophy

1 reference

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1 reference

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Rapid and non-genomic reduction of intracellular [Ca(2+)] induced by aldosterone in human bronchial epithelium

1 reference

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5 June 2018

Treatment of congestive heart failure: interfering the aldosterone-cardiac extracellular matrix relationship.

1 reference

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1 reference

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Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF

1 reference

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G13alpha-mediated PYK2 activation. PYK2 is a mediator of G13alpha -induced serum response element-dependent transcription.

1 reference

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The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators

1 reference

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Activation of G12/G13 results in shape change and Rho/Rho-kinase-mediated myosin light chain phosphorylation in mouse platelets

1 reference

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5 June 2018

Expression of functional angiotensin-converting enzyme and AT1 receptors in cultured human cardiac fibroblasts

1 reference

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Extracellular signal-regulated kinase activity is sustained early during human cytomegalovirus infection

1 reference

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5 June 2018

Non-genomic action of the mineralocorticoid aldosterone on cytosolic sodium in cultured kidney cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713569

5 June 2018

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713569

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Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

1 reference

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Src phosphorylates the insulin-like growth factor type I receptor on the autophosphorylation sites. Requirement for transformation by src.

1 reference

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A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

1 reference

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1 reference

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5 June 2018

Insulin-like growth factor-I regulates transcription of the elastin gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713569

5 June 2018

The 67-kD elastin/laminin-binding protein is related to an enzymatically inactive, alternatively spliced form of beta-galactosidase

1 reference

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Differential structural requirements for specific binding of nonpeptide and peptide antagonists to the AT1 angiotensin receptor. Identification of amino acid residues that determine binding of the antihypertensive drug losartan.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713569

5 June 2018

Mineralocorticoids, hypertension, and cardiac fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713569

5 June 2018

67-kD elastin-binding protein is a protective "companion" of extracellular insoluble elastin and intracellular tropoelastin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713569

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Distinctive effects of the carboxyl-terminal sequence of the insulin-like growth factor I receptor on its signaling functions

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Aldosterone-specific membrane receptors and rapid non-genomic actions of mineralocorticoids

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1 reference

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18 August 2018

Nongenomic effects of aldosterone in the human heart: interaction with angiotensin II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713569

18 August 2018

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1 reference

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Mechanism for aldosterone potentiation of angiotensin II-stimulated rat arterial smooth muscle cell proliferation

1 reference

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Aldosterone potentiates angiotensin II-induced signaling in vascular smooth muscle cells

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Limitation of Excessive Extracellular Matrix Turnover May Contribute to Survival Benefit of Spironolactone Therapy in Patients With Congestive Heart Failure

1 reference

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1 reference

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12 December 2020

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19372600

12 December 2020

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19372600

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19372600

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Antifibrotic effects of spironolactone in preventing myocardial fibrosis in systemic arterial hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/19372600

12 December 2020

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inferred from PubMed ID database lookup

Non-classical receptors for aldosterone in plasma membranes from pig kidneys

1 reference

https://pubmed.ncbi.nlm.nih.gov/19372600

12 December 2020

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19372600

12 December 2020

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19372600

12 December 2020

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Characterization and solubilization of novel aldosterone-binding proteins in porcine liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19372600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of angiotensin II and aldosterone on collagen gene expression and protein turnover in cardiac fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/19372600

12 December 2020

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Identifiers

10.1074/JBC.M109.008748

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

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