(Q41962039)

14 October 2017

Understanding and modulating opalescence and viscosity in a monoclonal antibody formulation (English)

1 reference

14 October 2017

1 reference

6

Theodore W Randolph

1 reference

14 October 2017

Branden A Salinas

1

1 reference

14 October 2017

Hasige A Sathish

2

1 reference

14 October 2017

Steven M Bishop

3

1 reference

14 October 2017

Nick Harn

4

1 reference

14 October 2017

John F Carpenter

5

1 reference

14 October 2017

language of work or name

English

0 references

publication date

1 January 2010

1 reference

Journal of Pharmaceutical Sciences

14 October 2017

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14 October 2017

99

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14 October 2017

1

1 reference

14 October 2017

82-93

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Effective hard particle model for the osmotic pressure of highly concentrated binary protein solutions

14 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927449

Protein phase behavior in aqueous solutions: crystallization, liquid-liquid phase separation, gels, and aggregates

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927449

Light-scattering studies of protein solutions: role of hydration in weak protein-protein interactions

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927449

Challenges in the development of high protein concentration formulations

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927449

Determination of the net charge (valence) of a protein: a fundamental but elusive parameter

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927449

Antibodies as therapeutic agents: vive la renaissance!

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927449

Effect of polyethylene glycol on the liquid-liquid phase transition in aqueous protein solutions

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927449

Understanding Nonidealities of the Osmotic Pressure of Concentrated Bovine Serum Albumin

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927449

The intrinsic viscosity of biological macromolecules. Progress in measurement, interpretation and application to structure in dilute solution

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927449

Free-Solvent Model of Osmotic Pressure Revisited: Application to Concentrated IgG Solution under Physiological Conditions

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927449

Binary liquid phase separation and critical phenomena in a protein/water solution

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927449

Hard quasispherical model for the viscosity of hemoglobin solutions

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927449

Reversible self-association of a concentrated monoclonal antibody solution mediated by Fab-Fab interaction that impacts solution viscosity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927449

High concentration formulations of recombinant human interleukin-1 receptor antagonist: II. Aggregation kinetics.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927449

Application of high-frequency rheology measurements for analyzing protein-protein interactions in high protein concentration solutions using a model monoclonal antibody (IgG2).

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927449

Reversible self-association increases the viscosity of a concentrated monoclonal antibody in aqueous solution

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927449

Predicting protein crystallization from a dilute solution property

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927449

Thermodynamic instability in supersaturated lysozyme solutions: effect of salt and role of concentration fluctuations

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927449

Determination of carbohydrate contents from excess light scattering

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927449

Viscosity analysis of the temperature dependence of the solution conformation of ovalbumin.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927449

A molecular model for the dependence of the osmotic pressure of bovine serum albumin upon concentration and pH.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3927449

Correlation between the osmotic second virial coefficient and solubility for equine serum albumin and ovalbumin

18 August 2018

1 reference

12 December 2020

Using phase transitions to investigate the effect of salts on protein interactions

1 reference

12 December 2020

Fast determination of conditions for maximum dynamic capacity in cation-exchange chromatography of human monoclonal antibodies

1 reference

12 December 2020

Oligomerization and phase separation in globular protein solutions

1 reference

12 December 2020

Use of T4 lysozyme charge mutants to examine electrophoretic models

1 reference

12 December 2020

Opalescent appearance of an IgG1 antibody at high concentrations and its relationship to noncovalent association

1 reference

12 December 2020

The effective hard particle model provides a simple, robust, and broadly applicable description of nonideal behavior in concentrated solutions of bovine serum albumin and other nonassociating proteins

1 reference

12 December 2020

Observation of critical phenomena in a protein-water solution

1 reference

12 December 2020

Negative second virial coefficients as predictors of protein crystal growth: evidence from sedimentation equilibrium studies that refutes the designation of those light scattering parameters as osmotic virial coefficients

1 reference

12 December 2020

Light scattering and phase behavior of lysozyme-poly(ethylene glycol) mixtures

1 reference

12 December 2020

Determination of protein charge by capillary zone electrophoresis

1 reference

12 December 2020

Identifiers

DOI

10.1002/JPS.21797

1 reference

14 October 2017

1 reference

14 October 2017

PubMed publication ID

19475558

1 reference