(Q41965533)

English

Identification of a new exosite involved in catalytic turnover by the streptokinase-plasmin activator complex during human plasminogen activation

scientific article published on 30 September 2009

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Identification of a new exosite involved in catalytic turnover by the streptokinase-plasmin activator complex during human plasminogen activation (English)

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

author name string

Rachna Aneja

1

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Manish Datt

2

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Balwinder Singh

3

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Shekhar Kumar

4

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Girish Sahni

5

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

language of work or name

0 references

publication date

30 September 2009

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

284

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

47

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

32642-32650

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Plasminogen substrate recognition by the streptokinase-plasminogen catalytic complex is facilitated by Arg253, Lys256, and Lys257 in the streptokinase beta-domain and kringle 5 of the substrate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

5 June 2018

Exosites in the substrate specificity of blood coagulation reactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

5 June 2018

Structure and interaction modes of thrombin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

5 June 2018

Molecular recognition mechanisms of thrombin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

5 June 2018

Structural diversity of streptokinase and activation of human plasminogen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

5 June 2018

Exosite-driven substrate specificity and function in coagulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

5 June 2018

Effects of deletion of streptokinase residues 48-59 on plasminogen activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

5 June 2018

Involvement of a nine-residue loop of streptokinase in the generation of macromolecular substrate specificity by the activator complex through interaction with substrate kringle domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

5 June 2018

Function of the central domain of streptokinase in substrate plasminogen docking and processing revealed by site-directed mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

5 June 2018

Crystal structure of streptokinase beta-domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

5 June 2018

Deletion of Ile1 changes the mechanism of streptokinase: evidence for the molecular sexuality hypothesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

5 June 2018

Crystal structure of the catalytic domain of human plasmin complexed with streptokinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

5 June 2018

Role of the amino-terminal region of streptokinase in the generation of a fully functional plasminogen activator complex probed with synthetic peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

5 June 2018

Mapping of the plasminogen binding site of streptokinase with short synthetic peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

5 June 2018

Converting tissue-type plasminogen activator into a zymogen.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

5 June 2018

Streptokinase-plasmin(ogen) activator assays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

5 June 2018

Identification of a plasminogen binding region in streptokinase that is necessary for the creation of a functional streptokinase-plasminogen activator complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

5 June 2018

Kinetic analysis of covalent hybrid plasminogen activators: effect of CNBr-degraded fibrinogen on kinetic parameters of Glu1-plasminogen activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

5 June 2018

Isolation and characterization of microplasminogen. A low molecular weight form of plasminogen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

5 June 2018

Extent of N-terminal methionine excision from Escherichia coli proteins is governed by the side-chain length of the penultimate amino acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

5 June 2018

Comparative fibrinolytic properties of staphylokinase and streptokinase in animal models of venous thrombosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

5 June 2018

Mechanism of activation of human plasminogen by the activator complex, streptokinase-plasmin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

5 June 2018

Activation of human plasminogen by equimolar levels of streptokinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

5 June 2018

Role of the 88-97 loop in plasminogen activation by streptokinase probed through site-specific mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

18 August 2018

Resolution of conformational activation in the kinetic mechanism of plasminogen activation by streptokinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

18 August 2018

Coupling of conformational and proteolytic activation in the kinetic mechanism of plasminogen activation by streptokinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

18 August 2018

Domain truncation studies reveal that the streptokinase-plasmin activator complex utilizes long range protein-protein interactions with macromolecular substrate to maximize catalytic turnover.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

18 August 2018

Function of the 90-loop (Thr90-Glu100) region of staphylokinase in plasminogen activation probed through site-directed mutagenesis and loop deletion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

18 August 2018

Localization of epitopes for monoclonal antibodies to urokinase-type plasminogen activator: relationship between epitope localization and effects of antibodies on molecular interactions of the enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

18 August 2018

Kinetics of activation of human plasminogen by different activator species at pH 7.4 and 37 degrees C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781679

18 August 2018

THE INTERACTION OF STREPTOKINASE WITH PLASMINOGEN. I. FUNCTIONAL PROPERTIES OF THE ACTIVATED ENZYME

1 reference

https://pubmed.ncbi.nlm.nih.gov/19801674

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allelic variants of streptokinase from Streptococcus pyogenes display functional differences in plasminogen activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19801674

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epsilon amino caproic acid inhibits streptokinase-plasminogen activator complex formation and substrate binding through kringle-dependent mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/19801674

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Streptokinase binds to human plasmin with high affinity, perturbs the plasmin active site, and induces expression of a substrate recognition exosite for plasminogen

1 reference

https://pubmed.ncbi.nlm.nih.gov/19801674

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zymogen activation in the streptokinase-plasminogen complex. Ile1 is required for the formation of a functional active site

1 reference

https://pubmed.ncbi.nlm.nih.gov/19801674

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Asp41-His48 region of streptokinase is important in binding to a substrate plasminogen

1 reference

https://pubmed.ncbi.nlm.nih.gov/19801674

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exosite binding tethers the macromolecular substrate to the prothrombinase complex and directs cleavage at two spatially distinct sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/19801674

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Streptokinase triggers conformational activation of plasminogen through specific interactions of the amino-terminal sequence and stabilizes the active zymogen conformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19801674

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preparation and Certain Properties of Highly Purified Streptokinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19801674

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the esterase activities of trypsin, plasmin, and thrombin on guanidinobenzoate esters. Titration of the enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19801674

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasminogen: Purification from Human Plasma by Affinity Chromatography

1 reference

https://pubmed.ncbi.nlm.nih.gov/19801674

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mechanism of activation of human plasminogen by streptokinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19801674

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of activation of human plasminogen by streptokinase. Presence of active center in streptokinase-plasminogen complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/19801674

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Computer-generated models of blood coagulation factor Xa, factor IXa, and thrombin based upon structural homology with other serine proteases

1 reference

https://pubmed.ncbi.nlm.nih.gov/19801674

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A virgin enzyme derived from human plasminogen. Specific cleavage of the arginyl-560-valyl peptide bond in the diisopropoxyphosphinyl virgin enzyme by plasminogen activators

1 reference

https://pubmed.ncbi.nlm.nih.gov/19801674

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complete amino acid sequence of streptokinase and its homology with serine proteases

1 reference

https://pubmed.ncbi.nlm.nih.gov/19801674

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interference of active site specific reagents in plasminogen-streptokinase active site formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19801674

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M109.046573

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

release_f4p6eqexiffsdbr3w4eqsyrste

1 reference

https://api.fatcat.wiki/v0/release/f4p6eqexiffsdbr3w4eqsyrste

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 October 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q41965533&oldid=1931084726"