(Q33221756)

24 July 2017

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title

Molecular recognition mechanisms of thrombin (English)

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24 July 2017

J A Huntington

1

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24 July 2017

publication date

1 August 2005

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Journal of Thrombosis and Haemostasis

24 July 2017

published in

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24 July 2017

volume

3

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24 July 2017

issue

8

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24 July 2017

page(s)

1861-1872

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The dynamics of thrombin formation

24 July 2017

cites work

1 reference

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21 January 2018

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Bovine thrombin complexed with an uncleavable analog of residues 7-19 of fibrinogen A alpha: geometry of the catalytic triad and interactions of the P1', P2', and P3' substrate residues

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Crystal structure of the complex between thrombin and the central "E" region of fibrin

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An extensive interaction interface between thrombin and factor V is required for factor V activation

21 January 2018

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Role of factor XIII in fibrin clot formation and effects of genetic polymorphisms

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Roles of low specificity and cofactor interaction sites on thrombin during factor XIII activation. Competition for cofactor sites on thrombin determines its fate.

21 January 2018

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Thrombin and platelet activation

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Crystal structure of the GpIbalpha-thrombin complex essential for platelet aggregation

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Modulation of alpha-thrombin function by distinct interactions with platelet glycoprotein Ibalpha

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Structural and functional mapping of the thrombin domain involved in the binding to the platelet glycoprotein Ib.

21 January 2018

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Identification of three tyrosine residues of glycoprotein Ib alpha with distinct roles in von Willebrand factor and alpha-thrombin binding

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Protease activated receptors 1 and 4 govern the responses of human platelets to thrombin

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Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes

21 January 2018

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Structure of the antithrombin-thrombin-heparin ternary complex reveals the antithrombotic mechanism of heparin.

21 January 2018

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Binding of thrombin to glycoprotein Ib accelerates the hydrolysis of Par-1 on intact platelets

21 January 2018

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Thrombin-mediated feedback activation of factor XI on the activated platelet surface is preferred over contact activation by factor XIIa or factor XIa.

21 January 2018

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Thrombin activation of factor XI on activated platelets requires the interaction of factor XI and platelet glycoprotein Ib alpha with thrombin anion-binding exosites I and II, respectively

21 January 2018

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21 January 2018

The Protein C Pathway

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Molecular recognition in the protein C anticoagulant pathway

21 January 2018

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21 January 2018

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Structural basis for the anticoagulant activity of the thrombin-thrombomodulin complex

21 January 2018

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Electrostatic dependence of the thrombin-thrombomodulin interaction

21 January 2018

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Energetics of thrombin-thrombomodulin interaction.

21 January 2018

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Presence and function of chondroitin-4-sulfate on recombinant human soluble thrombomodulin

21 January 2018

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Effect of thrombomodulin on the kinetics of the interaction of thrombin with substrates and inhibitors

21 January 2018

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The fourth epidermal growth factor-like domain of thrombomodulin interacts with the basic exosite of protein C.

21 January 2018

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The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex.

21 January 2018

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Thrombin interacts with thrombomodulin, protein C, and thrombin-activatable fibrinolysis inhibitor via specific and distinct domains

21 January 2018

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21 January 2018

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21 January 2018

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Thrombin and fibrinolysis

21 January 2018

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Activation of thrombin-activable fibrinolysis inhibitor requires epidermal growth factor-like domain 3 of thrombomodulin and is inhibited competitively by protein C.

21 January 2018

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Functional requirements for inhibition of thrombin by antithrombin III in the presence and absence of heparin

21 January 2018

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Crystal structure of thrombin bound to heparin

21 January 2018

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Mechanisms of glycosaminoglycan activation of the serpins in hemostasis

21 January 2018

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Structure of a serpin-protease complex shows inhibition by deformation

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01363.X

Crystal structures of native and thrombin-complexed heparin cofactor II reveal a multistep allosteric mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01363.X

Kinetic characterization of heparin-catalyzed and uncatalyzed inhibition of blood coagulation proteinases by antithrombin.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01363.X

Prothrombin is a cofactor for the binding of factor XI to the platelet surface and for platelet-mediated factor XI activation by thrombin

21 January 2018

1 reference

3 January 2024

https://opencitations.net/index/api/v1/citations/10.1021/BI972113+

Identifiers

DOI

10.1111/J.1538-7836.2005.01363.X

1 reference

24 July 2017

1 reference