(Q43705156)

English

Localization of epitopes for monoclonal antibodies to urokinase-type plasminogen activator: relationship between epitope localization and effects of antibodies on molecular interactions of the enzyme

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

Localization of epitopes for monoclonal antibodies to urokinase-type plasminogen activator: relationship between epitope localization and effects of antibodies on molecular interactions of the enzyme (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

molecular interaction

1 reference

based on heuristic

inferred from title

author name string

H H Petersen

1

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

M Hansen

2

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

S L Schousboe

3

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

P A Andreasen

4

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

language of work or name

0 references

publication date

1 August 2001

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

268

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

16

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

4430-4439

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

The urokinase-type plasminogen activator system in cancer metastasis: a review

1 reference

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The plasminogen activation system in tumor growth, invasion, and metastasis

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The crystal structure of the catalytic domain of human urokinase-type plasminogen activator

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Molecular evolution and domain structure of plasminogen-related growth factors (HGF/SF and HGF1/MSP)

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Plasminogen activator inhibitors: hormonally regulated serpins

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Implications of the three-dimensional structure of alpha 1-antitrypsin for structure and function of serpins

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An ester bond linking a fragment of a serine proteinase to its serpin inhibitor.

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A fluorescent probe study of plasminogen activator inhibitor-1. Evidence for reactive center loop insertion and its role in the inhibitory mechanism

1 reference

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Major proteinase movement upon stable serpin-proteinase complex formation

1 reference

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Mapping the serpin-proteinase complex using single cysteine variants of alpha1-proteinase inhibitor Pittsburgh

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Formation of the covalent serpin-proteinase complex involves translocation of the proteinase by more than 70 A and full insertion of the reactive center loop into beta-sheet A.

1 reference

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Structure of a serpin-protease complex shows inhibition by deformation

1 reference

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A serpin-induced extensive proteolytic susceptibility of urokinase-type plasminogen activator implicates distortion of the proteinase substrate-binding pocket and oxyanion hole in the serpin inhibitory mechanism

1 reference

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Heparin binding to the urokinase kringle domain

1 reference

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Systematic mutational analysis of the receptor-binding region of the human urokinase-type plasminogen activator.

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Immunohistochemical localization of urokinase- and tissue-type plasminogen activators in psoriatic skin

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Distinct localizations of urokinase-type plasminogen activator and its type 1 inhibitor under cultured human fibroblasts and sarcoma cells

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Prognostic significance of urokinase-type plasminogen activator and plasminogen activator inhibitor-1 in primary breast cancer.

1 reference

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Expression of human recombinant plasminogen activators enhances invasion and experimental metastasis of H-ras-transformed NIH 3T3 cells

1 reference

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Purification of zymogen to plasminogen activator from human glioblastoma cells by affinity chromatography with monoclonal antibody.

1 reference

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21 January 2018

Interconversions between active, inert and substrate forms of denatured/refolded type-1 plasminogen activator inhibitor

1 reference

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21 January 2018

Plasminogen activator inhibitor type-1: reactive center and amino-terminal heterogeneity determined by protein and cDNA sequencing.

1 reference

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The active conformation of plasminogen activator inhibitor 1, a target for drugs to control fibrinolysis and cell adhesion

1 reference

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Solution structure of the amino-terminal fragment of urokinase-type plasminogen activator

1 reference

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21 January 2018

Molecular mechanisms of plasminogen activation: bacterial cofactors provide clues

1 reference

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21 January 2018

Origins of the specificity of tissue-type plasminogen activator

1 reference

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Optimal subsite occupancy and design of a selective inhibitor of urokinase.

1 reference

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Trimeresurus stejnegeri snake venom plasminogen activator. Site-directed mutagenesis and molecular modeling.

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21 January 2018

Human plasminogen catalytic domain undergoes an unusual conformational change upon activation

1 reference

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Serpin-resistant mutants of human tissue-type plasminogen activator

1 reference

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Amino acid residues that affect interaction of tissue-type plasminogen activator with plasminogen activator inhibitor 1

1 reference

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Selective screening of a large phage display library of plasminogen activator inhibitor 1 mutants to localize interaction sites with either thrombin or the variable region 1 of tissue-type plasminogen activator.

1 reference

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Introduction of an RRHR motif into chicken urokinase-type plasminogen activator (ch-uPA) confers sensitivity to plasminogen activator inhibitor (PAI)-1 and PAI-2 and allows ch-uPA-mediated extracellular matrix degradation to be controlled by PAI-1

1 reference

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The variable region-1 from tissue-type plasminogen activator confers specificity for plasminogen activator inhibitor-1 to thrombin by facilitating catalysis: release of a kinetic block by a heterologous protein surface loop

1 reference

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Serpin-protease complexes are trapped as stable acyl-enzyme intermediates

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Structural insights into serpin-protease complexes reveal the inhibitory mechanism of serpins

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The structure of a serpin-protease complex revealed by intramolecular distance measurements using donor-donor energy migration and mapping of interaction sites

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Type-1 plasminogen-activator inhibitor -- conformational differences between latent, active, reactive-centre-cleaved and plasminogen-activator-complexed forms, as probed by proteolytic susceptibility

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Serine 380 (P14) --> glutamate mutation activates antithrombin as an inhibitor of factor Xa

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Immunohistochemical localization of urokinase-type plasminogen activator, type-1 plasminogen-activator inhibitor, urokinase receptor and alpha(2)-macroglobulin receptor in human breast carcinomas

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Substrate specificity of tissue type plasminogen activator. Characterization of the fibrin independent specificity of t-PA for plasminogen

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Distinct mechanisms contribute to stringent substrate specificity of tissue-type plasminogen activator

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Rational design of complex formation between plasminogen activator inhibitor-1 and its target proteinases

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Identifiers

10.1046/J.1432-1327.2001.02365.X

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

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