(Q41993280)

20 February 2018

title

FLEXITau: Quantifying Post-translational Modifications of Tau Protein in Vitro and in Human Disease (English)

1 reference

20 February 2018

8

Eckhard Mandelkow

1 reference

20 February 2018

6

William W Seeley

1 reference

20 February 2018

Kenneth S. Kosik

7

object named as

Kenneth S Kosik

1 reference

20 February 2018

Judith A Steen

10

object named as

Judith A Steen

1 reference

20 February 2018

1

Waltraud Mair

1 reference

20 February 2018

Jan Muntel

2

1 reference

20 February 2018

Katharina Tepper

3

1 reference

20 February 2018

Shaojun Tang

4

1 reference

20 February 2018

Jacek Biernat

5

1 reference

20 February 2018

Hanno Steen

9

1 reference

20 February 2018

language of work or name

English

0 references

publication date

15 February 2016

1 reference

20 February 2018

published in

Analytical Chemistry

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20 February 2018

volume

88

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20 February 2018

issue

7

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20 February 2018

page(s)

3704-3714

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20 February 2018

Oligomer formation of tau protein hyperphosphorylated in cells

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Quantitative phosphoproteomics of Alzheimer's disease reveals cross-talk between kinases and small heat shock proteins.

5 June 2018

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Specificity of anti-tau antibodies when analyzing mice models of Alzheimer's disease: problems and solutions

5 June 2018

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Post-translational modifications in Alzheimer's disease and the potential for new biomarkers

5 June 2018

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Identification of the sites of tau hyperphosphorylation and activation of tau kinases in synucleinopathies and Alzheimer's diseases

5 June 2018

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The importance of tau phosphorylation for neurodegenerative diseases

5 June 2018

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Synapsin-1 and tau reciprocal O-GlcNAcylation and phosphorylation sites in mouse brain synaptosomes

5 June 2018

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Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation.

5 June 2018

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Tau protein kinases: involvement in Alzheimer's disease

5 June 2018

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Using iRT, a normalized retention time for more targeted measurement of peptides

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5808556

Dual modification of Alzheimer's disease PHF-tau protein by lysine methylation and ubiquitylation: a mass spectrometry approach

5 June 2018

1 reference

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Comparative analysis of Erk phosphorylation suggests a mixed strategy for measuring phospho-form distributions

5 June 2018

1 reference

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The acetylation of tau inhibits its function and promotes pathological tau aggregation

5 June 2018

1 reference

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Post-translational modifications of tau protein: implications for Alzheimer's disease.

5 June 2018

1 reference

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Acetylation of tau inhibits its degradation and contributes to tauopathy

5 June 2018

1 reference

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Advances in tau-focused drug discovery for Alzheimer's disease and related tauopathies

5 June 2018

1 reference

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Full dynamic range proteome analysis of S. cerevisiae by targeted proteomics

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5808556

Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasma

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5808556

FLEXIQuant: a novel tool for the absolute quantification of proteins, and the simultaneous identification and quantification of potentially modified peptides

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5808556

Tau phosphorylation: the therapeutic challenge for neurodegenerative disease

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5808556

Differential regulation of dynein and kinesin motor proteins by tau

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5808556

Investigating quantitation of phosphorylation using MALDI-TOF mass spectrometry

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5808556

Quantitative, multiplexed assays for low abundance proteins in plasma by targeted mass spectrometry and stable isotope dilution

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5808556

Decoding protein modifications using top-down mass spectrometry

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5808556

Extending top-down mass spectrometry to proteins with masses greater than 200 kilodaltons

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5808556

Role of tau protein in both physiological and pathological conditions.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5808556

Glycosylation of microtubule-associated protein tau in Alzheimer's disease brain

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5808556

The development of cell processes induced by tau protein requires phosphorylation of serine 262 and 356 in the repeat domain and is inhibited by phosphorylation in the proline-rich domains

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5808556

New phosphorylation sites identified in hyperphosphorylated tau (paired helical filament-tau) from Alzheimer's disease brain using nanoelectrospray mass spectrometry

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5808556

Sequential phosphorylation of Tau by glycogen synthase kinase-3beta and protein kinase A at Thr212 and Ser214 generates the Alzheimer-specific epitope of antibody AT100 and requires a paired-helical-filament-like conformation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5808556

Microtubule-associated protein function: lessons from expression in Spodoptera frugiperda cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5808556

Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5808556

Processes induced by tau expression in Sf9 cells have an axon-like microtubule organization

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5808556

Ubiquitination and abnormal phosphorylation of paired helical filaments in Alzheimer's disease

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5808556

Tau post-translational modifications in wild-type and human amyloid precursor protein transgenic mice

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5808556

Quantification of tau in cerebrospinal fluid by immunoaffinity enrichment and tandem mass spectrometry.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5808556

A sensitive mass spectrometric method for hypothesis-driven detection of peptide post-translational modifications: multiple reaction monitoring-initiated detection and sequencing (MIDAS).

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5808556

Direct analysis of tau from PSP brain identifies new phosphorylation sites and a major fragment of N-terminally cleaved tau containing four microtubule-binding repeats.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5808556

Novel phosphorylation sites in tau from Alzheimer brain support a role for casein kinase 1 in disease pathogenesis

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5808556

Alzheimer disease-specific conformation of hyperphosphorylated paired helical filament-Tau is polyubiquitinated through Lys-48, Lys-11, and Lys-6 ubiquitin conjugation.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5808556

Glycosylation of microtubule-associated protein tau: an abnormal posttranslational modification in Alzheimer's disease.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5808556

Microtubule-associated protein tau. Abnormal phosphorylation of a non-paired helical filament pool in Alzheimer disease.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5808556

Platform for Establishing Interlaboratory Reproducibility of Selected Reaction Monitoring-Based Mass Spectrometry Peptide Assays

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5808556

10.1021/ACS.ANALCHEM.5B04509

2 December 2018

Identifiers

DOI

1 reference

20 February 2018

release_azd7wrv6fvckdkvcp7b7ssh4b4

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/azd7wrv6fvckdkvcp7b7ssh4b4

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

5808556

1 reference

20 February 2018

PubMed publication ID

26877193

1 reference

20 February 2018