(Q42004480)

15 October 2017

Dual melanocortin-4 receptor and GLP-1 receptor agonism amplifies metabolic benefits in diet-induced obese mice (English)

1 reference

15 October 2017

0 references

Christoffer Clemmensen

1

1 reference

15 October 2017

12

Matthias H Tschöp

1 reference

15 October 2017

0 references

5

Beata Legutko

1 reference

15 October 2017

14

Timo D Müller

1 reference

15 October 2017

Brian Finan

2

1 reference

15 October 2017

Katrin Fischer

3

1 reference

15 October 2017

Robby Zachariah Tom

4

1 reference

15 October 2017

Laura Sehrer

6

1 reference

15 October 2017

Daniela Heine

7

1 reference

15 October 2017

Niklas Grassl

8

1 reference

15 October 2017

Carola W Meyer

9

1 reference

15 October 2017

Bart Henderson

10

1 reference

15 October 2017

Susanna M Hofmann

11

1 reference

15 October 2017

Lex H T Van der Ploeg

13

1 reference

15 October 2017

4 February 2015

1 reference

15 October 2017

EMBO Molecular Medicine

1 reference

15 October 2017

7

1 reference

15 October 2017

3

1 reference

15 October 2017

288-298

1 reference

Coinfusion of low-dose GLP-1 and glucagon in man results in a reduction in food intake

15 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

Combating the dual burden: therapeutic targeting of common pathways in obesity and type 2 diabetes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

The melanocortin-4 receptor as target for obesity treatment: a systematic review of emerging pharmacological therapeutic options

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

New pharmacological approaches for obesity management.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

The role of glucagon-like peptide-1 impairment in obesity and potential therapeutic implications

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

Emerging combinatorial hormone therapies for the treatment of obesity and T2DM.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

Targeted estrogen delivery reverses the metabolic syndrome

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

Chronic treatment with a melanocortin-4 receptor agonist causes weight loss, reduces insulin resistance, and improves cardiovascular function in diet-induced obese rhesus macaques

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

GLP-1 receptor agonists for individualized treatment of type 2 diabetes mellitus

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

Anti-obesity drugs: past, present and future

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

Effects of glucagon-like peptide-1 receptor agonists on weight loss: systematic review and meta-analyses of randomised controlled trials

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

A guide to analysis of mouse energy metabolism

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

Health and economic burden of the projected obesity trends in the USA and the UK.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

Long-acting glucagon-like peptide 1 receptor agonists: a review of their efficacy and tolerability

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

Combination drugs for treating obesity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

The melanocortin-4 receptor: physiology, pharmacology, and pathophysiology.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

Glucagon-like peptide 1/glucagon receptor dual agonism reverses obesity in mice

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

Defective lipid delivery modulates glucose tolerance and metabolic response to diet in apolipoprotein E-deficient mice

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

Responsiveness to peripherally administered melanocortins in lean and obese mice

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

A simple method for the isolation and purification of total lipides from animal tissues

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

Central melanocortin receptors regulate insulin action

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

Obesity as a medical problem

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

A frameshift mutation in MC4R associated with dominantly inherited human obesity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

Post-translational processing of proopiomelanocortin in the pituitary and in the brain

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

Targeted disruption of the melanocortin-4 receptor results in obesity in mice

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

A new glucagon and GLP-1 co-agonist eliminates obesity in rodents

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

Divergence of melanocortin pathways in the control of food intake and energy expenditure.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4364946

Effect of intracerebroventricular alpha-MSH on food intake, adiposity, c-Fos induction, and neuropeptide expression

17 August 2018

1 reference

12 December 2020

Restoration of leptin responsiveness in diet-induced obese mice using an optimized leptin analog in combination with exendin-4 or FGF21

1 reference

12 December 2020

Unimolecular dual incretins maximize metabolic benefits in rodents, monkeys, and humans.

1 reference

12 December 2020

GLP-1/glucagon coagonism restores leptin responsiveness in obese mice chronically maintained on an obesogenic diet

1 reference

12 December 2020

Role of the melanocortin-4 receptor in metabolic rate and food intake in mice

1 reference

12 December 2020

Identifiers

DOI

10.15252/EMMM.201404508

1 reference

15 October 2017

1 reference

15 October 2017

1 reference