(Q42031891)

15 October 2017

Cell-cell interaction networks regulate blood stem and progenitor cell fate (English)

1 reference

15 October 2017

Cell–cell interaction

1 reference

6

Peter W Zandstra

1 reference

15 October 2017

Daniel C Kirouac

1

1 reference

15 October 2017

Gerard J Madlambayan

2

1 reference

15 October 2017

Mei Yu

3

1 reference

15 October 2017

Edward A Sykes

4

1 reference

15 October 2017

Caryn Ito

5

1 reference

15 October 2017

language of work or name

1 reference

28 July 2009

1 reference

Molecular Systems Biology

15 October 2017

1 reference

15 October 2017

5

1 reference

15 October 2017

293

1 reference

Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data

15 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Detection of functional haematopoietic stem cell niche using real-time imaging.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

The systematic production of cells for cell therapies

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Characterization and quantification of clonal heterogeneity among hematopoietic stem cells: a model-based approach

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Regulatory networks define phenotypic classes of human stem cell lines

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Unilineage model of hematopoiesis predicts self-renewal of stem and progenitor cells based on ex vivo growth data

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Microenvironment determines lineage fate in a human model of MLL-AF9 leukemia

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Steel factor coordinately regulates the molecular signature and biologic function of hematopoietic stem cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Stems cells and the pathways to aging and cancer

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Universally sloppy parameter sensitivities in systems biology models

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Negative autoregulation by FAS mediates robust fetal erythropoiesis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Modeling the initiation and progression of human acute leukemia in mice

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Lineage specification of hematopoietic stem cells: mathematical modeling and biological implications

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Understanding cellular networks to improve hematopoietic stem cell expansion cultures

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

The continuum model of marrow stem cell regulation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Bone-marrow haematopoietic-stem-cell niches

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Deregulated TGF-beta signaling in leukemogenesis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Direct evidence for cooperating genetic events in the leukemic transformation of normal human hematopoietic cells.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Dynamics of chronic myeloid leukaemia.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

In vitro and in vivo expansion of hematopoietic stem cells.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Identification of hematopoietic stem/progenitor cells: strength and drawbacks of functional assays

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

A benchmark for methods in reverse engineering and model discrimination: problem formulation and solutions

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Importance of input perturbations and stochastic gene expression in the reverse engineering of genetic regulatory networks: insights from an identifiability analysis of an in silico network

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Regulation of hematopoiesis in a sea of chemokine family members with a plethora of redundant activities

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Cluster analysis and display of genome-wide expression patterns

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Expansion in vitro of transplantable human cord blood stem cells demonstrated using a quantitative assay of their lympho-myeloid repopulating activity in nonobese diabetic-scid/scid mice

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Robustness in simple biochemical networks

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Cytokine manipulation of primitive human hematopoietic cell self-renewal

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Donor-to-donor variability in the expansion potential of human bone marrow cells is reduced by accessory cells but not by soluble growth factors.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Retention of quiescent hematopoietic cells with high proliferative potential during ex vivo stem cell culture.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Multiexponential, multicompartmental, and noncompartmental modeling. II. Data analysis and statistical considerations

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Parameter sensitivity as a criterion for evaluating and comparing the performance of biochemical systems.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

IFNalpha activates dormant haematopoietic stem cells in vivo.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

TGF-beta as a candidate bone marrow niche signal to induce hematopoietic stem cell hibernation.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

The effect of bleeding on hematopoietic stem cell cycling and self-renewal.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Analysis of cell differentiation by division tracking cytometry.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Clinically relevant expansion of hematopoietic stem cells with conserved function in a single-use, closed-system bioprocess.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Dynamic modeling of imatinib-treated chronic myeloid leukemia: functional insights and clinical implications.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Dynamic changes in cellular and microenvironmental composition can be controlled to elicit in vitro human hematopoietic stem cell expansion.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Progenitor cells divide symmetrically to generate new colony‐forming cells and clonal heterogeneity

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Human haematopoiesis in steady state and following intense perturbations

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

A novel dynamic model of hematopoietic stem cell organization based on the concept of within-tissue plasticity.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Cell kinetic status of haematopoietic stem cells.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

The growth response of Lin-Thy-1+ hematopoietic progenitors to cytokines is determined by the balance between synergy of multiple stimulators and negative cooperation of multiple inhibitors.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Mechanisms that regulate the cell cycle status of very primitive hematopoietic cells in long-term human marrow cultures. I. Stimulatory role of a variety of mesenchymal cell activators and inhibitory role of TGF-beta.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724979

Platelet-released supernatants enhance hematopoietic stem cell proliferation in vitro

17 August 2018

1 reference

12 December 2020

Mechanisms of haemopoietic stem cell proliferation control

1 reference

12 December 2020

Serum supplement, inoculum cell density, and accessory cell effects are dependent on the cytokine combination selected to expand human HPCs ex vivo

1 reference

12 December 2020

Maintenance and proliferation control of primitive hemopoietic progenitors in long-term cultures of human marrow cells

1 reference

12 December 2020

Effects of CD34+ cell selection and perfusion on ex vivo expansion of peripheral blood mononuclear cells

1 reference

12 December 2020

Numerous growth factors, cytokines, and chemokines are secreted by human CD34+ cells, myeloblasts, erythroblasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner

1 reference

12 December 2020

Kinetic model of a bone-marrow stem-cell population

1 reference

12 December 2020

A regulatory mechanism for the number of pluripotential haemopoietic progenitor cells in mice

1 reference

12 December 2020

Resolution of pluripotential intermediates in murine hematopoietic differentiation by global complementary DNA amplification from single cells: confirmation of assignments by expression profiling of cytokine receptor transcripts

1 reference

12 December 2020

Sensitivity of myeloid progenitors to NK-cell depletion

1 reference

12 December 2020

Differential kinetics of primitive hematopoietic cells assayed in vitro and in vivo during serum-free suspension culture of CD34+ blood progenitor cells

1 reference

12 December 2020

Elevated telomerase activity and minimal telomere loss in cord blood long-term cultures with extensive stem cell replication

1 reference

12 December 2020

Hematopoietic stem cells expand during serial transplantation in vivo without apparent exhaustion

1 reference

12 December 2020

Ex vivo expansion of human umbilical cord blood and peripheral blood CD34(+) hematopoietic stem cells

1 reference

12 December 2020

Frequent harvesting from perfused bone marrow cultures results in increased overall cell and progenitor expansion

1 reference

12 December 2020

Can Dexter cultures support stem cell proliferation?

1 reference

12 December 2020

Growth kinetics of progenitor cell-enriched hematopoietic cell populations in long-term liquid cultures under continuous removal of mature cells

1 reference

12 December 2020

Defining optimum conditions for the ex vivo expansion of human umbilical cord blood cells. Influences of progenitor enrichment, interference with feeder layers, early-acting cytokines and agitation of culture vessels

1 reference

12 December 2020

Functional analysis of initial cell divisions defines the subsequent fate of individual human CD34(+)CD38(-) cells

1 reference

12 December 2020

Identifiers

DOI

10.1038/MSB.2009.49

1 reference

15 October 2017

1 reference

15 October 2017

PubMed publication ID

19638974

1 reference