(Q42040655)

15 October 2017

Site-specific integration in CHO cells mediated by CRISPR/Cas9 and homology-directed DNA repair pathway (English)

1 reference

15 October 2017

0 references

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25712033%20AND%20SRC:MED&resulttype=core&format=json

Thomas Beuchert Kallehauge

4 June 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25712033%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Lasse Ebdrup Pedersen

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25712033%20AND%20SRC:MED&resulttype=core&format=json

Helene Faustrup Kildegaard

4 June 2020

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25712033%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

author name string

Jae Seong Lee

1

1 reference

15 October 2017

language of work or name

English

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publication date

25 February 2015

1 reference

15 October 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25712033%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25712033%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

page(s)

8572

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Creative Commons Attribution 4.0 International

4 June 2020

copyright license

start time

25 February 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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exact match

https://scigraph.springernature.com/pub.10.1038/srep08572

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cites work

Assaying break and nick-induced homologous recombination in mammalian cells using the DR-GFP reporter and Cas9 nucleases

1 reference

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Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.

5 June 2018

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A versatile system for USER cloning-based assembly of expression vectors for mammalian cell engineering

5 June 2018

1 reference

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CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences

5 June 2018

1 reference

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Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing

5 June 2018

1 reference

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Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells

5 June 2018

1 reference

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Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks.

5 June 2018

1 reference

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Genome engineering with targetable nucleases

5 June 2018

1 reference

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Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

5 June 2018

1 reference

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Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

5 June 2018

1 reference

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CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4339809

Genomic landscapes of Chinese hamster ovary cell lines as revealed by the Cricetulus griseus draft genome

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4339809

DNA targeting specificity of RNA-guided Cas9 nucleases

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4339809

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

5 June 2018

1 reference

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Engineering Chinese hamster ovary (CHO) cells for producing recombinant proteins with simple glycoforms by zinc-finger nuclease (ZFN)-mediated gene knockout of mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (Mgat1).

5 June 2018

1 reference

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RNA-guided human genome engineering via Cas9

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4339809

Multiplex genome engineering using CRISPR/Cas systems

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4339809

In vivo cleavage of transgene donors promotes nuclease-mediated targeted integration

5 June 2018

1 reference

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A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

5 June 2018

1 reference

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The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4339809

A TALE nuclease architecture for efficient genome editing

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4339809

Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4339809

Zinc-finger nuclease-driven targeted integration into mammalian genomes using donors with limited chromosomal homology

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4339809

Generation of site-specific retargeting platform cell lines for drug discovery using phiC31 and R4 integrases

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4339809

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4339809

An efficient and targeted gene integration system for high-level antibody expression

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4339809

Production of recombinant protein therapeutics in cultivated mammalian cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4339809

Five Lec1 CHO cell mutants have distinct Mgat1 gene mutations that encode truncated N-acetylglucosaminyltransferase I.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4339809

Construction of engineered CHO strains for high-level production of recombinant proteins

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4339809

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

5 June 2018

1 reference

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Position effects on eukaryotic gene expression

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4339809

Accelerating genome editing in CHO cells using CRISPR Cas9 and CRISPy, a web-based target finding tool

5 June 2018

1 reference

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Surrogate reporter-based enrichment of cells containing RNA-guided Cas9 nuclease-induced mutations

17 August 2018

1 reference

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17 August 2018

1 reference

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Site-specific integration and tailoring of cassette design for sustainable gene transfer.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4339809

Characterization of chimeric antibody producing CHO cells in the course of dihydrofolate reductase-mediated gene amplification and their stability in the absence of selective pressure

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4339809

17 August 2018

Identifiers

DOI

10.1038/SREP08572

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25712033%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

4 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25712033%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

PubMed publication ID

25712033

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25712033%20AND%20SRC:MED&resulttype=core&format=json