(Q42043872)

English

Active state-like conformational elements in the beta2-AR and a photoactivated intermediate of rhodopsin identified by dynamic properties of GPCRs

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Active state-like conformational elements in the beta2-AR and a photoactivated intermediate of rhodopsin identified by dynamic properties of GPCRs (English)

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

G protein-coupled receptor

0 references

photoactivation

0 references

0 references

author name string

Daniel S Han

1

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Simon X Wang

2

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Harel Weinstein

3

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

language of work or name

0 references

publication date

18 June 2008

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

47

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

28

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

7317-7321

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

Ligand-stabilized conformational states of human beta(2) adrenergic receptor: insight into G-protein-coupled receptor activation

1 reference

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5 June 2018

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664832

5 June 2018

GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function

1 reference

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5 June 2018

Crystal structure of the human beta2 adrenergic G-protein-coupled receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664832

5 June 2018

Conformational complexity of G-protein-coupled receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664832

5 June 2018

G protein coupled receptor structure and activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664832

5 June 2018

Dynamic models of G-protein coupled receptor dimers: indications of asymmetry in the rhodopsin dimer from molecular dynamics simulations in a POPC bilayer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664832

5 June 2018

Crystal structure of a photoactivated deprotonated intermediate of rhodopsin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664832

5 June 2018

Pharmacogenomic and structural analysis of constitutive g protein-coupled receptor activity.

1 reference

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GROMACS: fast, flexible, and free

1 reference

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5 June 2018

The structure and dynamics of GPCR oligomers: a new focus in models of cell-signaling mechanisms and drug design.

1 reference

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5 June 2018

Conformational sampling and dynamics of membrane proteins from 10-nanosecond computer simulations.

1 reference

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5 June 2018

Structural origins of constitutive activation in rhodopsin: Role of the K296/E113 salt bridge

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664832

5 June 2018

Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: molecular modeling and mutagenesis approaches to receptor structure and function

1 reference

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5 June 2018

Mutation of tyrosine in the conserved NPXXY sequence leads to constitutive phosphorylation and internalization, but not signaling, of the human B2 bradykinin receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664832

5 June 2018

Role of the conserved NPxxY(x)5,6F motif in the rhodopsin ground state and during activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664832

5 June 2018

Constitutive activity of G-protein-coupled receptors: cause of disease and common property of wild-type receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664832

5 June 2018

Conserved helix 7 tyrosine acts as a multistate conformational switch in the 5HT2C receptor. Identification of a novel "locked-on" phenotype and double revertant mutations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664832

5 June 2018

Functional role of internal water molecules in rhodopsin revealed by X-ray crystallography.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664832

5 June 2018

Advances in Determination of a High-Resolution Three-Dimensional Structure of Rhodopsin, a Model of G-Protein-Coupled Receptors (GPCRs)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664832

5 June 2018

Hinges, swivels and switches: the role of prolines in signalling via transmembrane alpha-helices

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664832

5 June 2018

Crystal structure of rhodopsin: A G protein-coupled receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664832

5 June 2018

VMD: visual molecular dynamics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664832

5 June 2018

Essential dynamics of proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664832

5 June 2018

Helix 8 Leu in the CB1 cannabinoid receptor contributes to selective signal transduction mechanisms

1 reference

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17 August 2018

Linkage between the intramembrane H-bond network around aspartic acid 83 and the cytosolic environment of helix 8 in photoactivated rhodopsin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664832

17 August 2018

Structure and function in rhodopsin: mapping light-dependent changes in distance between residue 316 in helix 8 and residues in the sequence 60-75, covering the cytoplasmic end of helices TM1 and TM2 and their connection loop CL1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664832

17 August 2018

Structure and function in rhodopsin: mapping light-dependent changes in distance between residue 65 in helix TM1 and residues in the sequence 306-319 at the cytoplasmic end of helix TM7 and in helix H8.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664832

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Constitutive activation of opsin by mutation of methionine 257 on transmembrane helix 6.

1 reference

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17 August 2018

The essential dynamics of thermolysin: Confirmation of the hinge-bending motion and comparison of simulations in vacuum and water

1 reference

https://pubmed.ncbi.nlm.nih.gov/18558776

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three-dimensional representations of G protein-coupled receptor structures and mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/18558776

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/BI800442G

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 October 2017

ResearchGate publication ID

0 references

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