(Q42111101)

16 October 2017

Effect of itraconazole on the pharmacokinetics and pharmacodynamics of a single oral dose of brotizolam (English)

1 reference

16 October 2017

1 reference

ChEBI release 2020-05-28

1 reference

1 reference

T Osanai

1

1 reference

16 October 2017

T Ohkubo

2

1 reference

16 October 2017

N Yasui

3

1 reference

16 October 2017

T Kondo

4

1 reference

16 October 2017

S Kaneko

5

1 reference

16 October 2017

language of work or name

English

0 references

publication date

1 November 2004

1 reference

British Journal of Clinical Pharmacology

16 October 2017

1 reference

16 October 2017

58

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16 October 2017

5

1 reference

16 October 2017

476-481

1 reference

Interaction with P-glycoprotein and transport of erythromycin, midazolam and ketoconazole in Caco-2 cells

16 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884630

P-glycoprotein-mediated transport of itraconazole across the blood-brain barrier.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884630

Cytochrome P4503A (CYP3A) metabolism: prediction of in vivo activity in humans

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884630

Effect of itraconazole on the pharmacokinetics and pharmacodynamics of zopiclone

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884630

P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884630

A kinetic and dynamic study of oral alprazolam with and without erythromycin in humans: in vivo evidence for the involvement of CYP3A4 in alprazolam metabolism.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884630

Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884630

Oral triazolam is potentially hazardous to patients receiving systemic antimycotics ketoconazole or itraconazole

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884630

Noninvasive tests of CYP3A enzymes

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884630

Pharmacokinetics of brotizolam in healthy subjects following intravenous and oral administration

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884630

Pharmacokinetics and metabolism of brotizolam in humans

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884630

Metabolic fate of [14C]-brotizolam in the rat, dog, monkey and man.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884630

Pharmacological action of some known and possible metabolites of brotizolam.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884630

Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884630

Absorption rate, blood concentrations, and early response to oral chlordiazepoxide

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884630

Determination of itraconazole in human plasma by high-performance liquid chromatography with solid-phase extraction

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884630

Itraconazole increases but grapefruit juice greatly decreases plasma concentrations of celiprolol

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884630

Midazolam alpha-hydroxylation by human liver microsomes in vitro: inhibition by calcium channel blockers, itraconazole and ketoconazole.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884630

Acute tolerance to triazolam during continuous and step infusions: estimation of the effect offset rate constant.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884630

Oral triazolam is potentially hazardous to patients receiving systemic antimycotics ketoconazole or itraconazole

17 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2004.02208.X

Identification of human cytochrome P450 isoforms involved in the metabolism of brotizolam

21 January 2018

1 reference

12 December 2020

Itraconazole decreases renal clearance of digoxin

1 reference

12 December 2020

The UKU side effect rating scale. A new comprehensive rating scale for psychotropic drugs and a cross-sectional study of side effects in neuroleptic-treated patients

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of alprazolam following single and multiple oral doses of a sustained-release formulation

1 reference

12 December 2020

Triazolam biotransformation by human liver microsomes in vitro: effects of metabolic inhibitors and clinical confirmation of a predicted interaction with ketoconazole

1 reference

12 December 2020

The effect of ingestion time interval on the interaction between itraconazole and triazolam

1 reference

12 December 2020

10.1111/J.1365-2125.2004.02208.X

Identifiers

DOI

1 reference

16 October 2017

1 reference

16 October 2017

PubMed publication ID

15521894

1 reference