(Q42134405)

17 October 2017

Hindbrain leptin and glucagon-like-peptide-1 receptor signaling interact to suppress food intake in an additive manner (English)

1 reference

17 October 2017

S Zhao

1

1 reference

17 October 2017

S E Kanoski

2

1 reference

17 October 2017

J Yan

3

1 reference

17 October 2017

H J Grill

4

1 reference

17 October 2017

M R Hayes

5

1 reference

17 October 2017

language of work or name

English

0 references

publication date

17 January 2012

1 reference

International Journal of Obesity

17 October 2017

1 reference

17 October 2017

36

1 reference

17 October 2017

12

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17 October 2017

1522-1528

1 reference

https://scigraph.springernature.com/pub.10.1038/ijo.2011.265

17 October 2017

0 references

cites work

Peripheral and central GLP-1 receptor populations mediate the anorectic effects of peripherally administered GLP-1 receptor agonists, liraglutide and exendin-4.

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Intracellular signals mediating the food intake-suppressive effects of hindbrain glucagon-like peptide-1 receptor activation

29 May 2018

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Behavioral and pharmacologic therapies for obesity

29 May 2018

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Dose combinations of exendin-4 and salmon calcitonin produce additive and synergistic reductions in food intake in nonhuman primates

29 May 2018

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Brainstem mechanisms of amylin-induced anorexia

29 May 2018

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Role of the glucagon-like-peptide-1 receptor in the control of energy balance

29 May 2018

1 reference

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"Weighing in" on synergy: preclinical research on neurohormonal anti-obesity combinations

29 May 2018

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Endogenous leptin signaling in the caudal nucleus tractus solitarius and area postrema is required for energy balance regulation

29 May 2018

1 reference

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Leptin and the systems neuroscience of meal size control

29 May 2018

1 reference

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The nucleus tractus solitarius: a portal for visceral afferent signal processing, energy status assessment and integration of their combined effects on food intake

29 May 2018

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Efficacy and safety of the human glucagon-like peptide-1 analog liraglutide in combination with metformin and thiazolidinedione in patients with type 2 diabetes (LEAD-4 Met+TZD).

29 May 2018

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Endogenous hindbrain glucagon-like peptide-1 receptor activation contributes to the control of food intake by mediating gastric satiation signaling

29 May 2018

1 reference

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Dorsal hindbrain 5'-adenosine monophosphate-activated protein kinase as an intracellular mediator of energy balance

29 May 2018

1 reference

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Hindbrain leptin stimulation induces anorexia and hyperthermia mediated by hindbrain melanocortin receptors

29 May 2018

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Intrameal hepatic portal and intraperitoneal infusions of glucagon-like peptide-1 reduce spontaneous meal size in the rat via different mechanisms

29 May 2018

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Leptin responsiveness restored by amylin agonism in diet-induced obesity: evidence from nonclinical and clinical studies

29 May 2018

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Caudal brainstem processing is sufficient for behavioral, sympathetic, and parasympathetic responses driven by peripheral and hindbrain glucagon-like-peptide-1 receptor stimulation

29 May 2018

1 reference

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Leptin activates hypothalamic acetyl-CoA carboxylase to inhibit food intake

29 May 2018

1 reference

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The Physiology of Glucagon-like Peptide 1

29 May 2018

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Lifestyle modification for the management of obesity

29 May 2018

1 reference

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Gut peptide signaling in the controls of food intake

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335926

Brainstem mechanisms integrating gut-derived satiety signals and descending forebrain information in the control of meal size

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335926

AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335926

Evidence that the caudal brainstem is a target for the inhibitory effect of leptin on food intake

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335926

Selective deletion of leptin receptor in neurons leads to obesity

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335926

Central leptin modulates behavioral and neural responsivity to CCK.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335926

Leptin interacts with glucagon-like peptide-1 neurons to reduce food intake and body weight in rodents

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335926

29 May 2018

1 reference

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Chronically decerebrate rats demonstrate satiation but not bait shyness

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335926

Comparative effects of the long-acting GLP-1 receptor ligands, liraglutide and exendin-4, on food intake and body weight suppression in rats

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335926

A randomized trial of lifestyle modification and taranabant for maintaining weight loss achieved with a low-calorie diet

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335926

Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335926

A new glucagon and GLP-1 co-agonist eliminates obesity in rodents

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335926

Rational design of a combination medication for the treatment of obesity

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335926

Amylin-mediated restoration of leptin responsiveness in diet-induced obesity: magnitude and mechanisms

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335926

The GLP-1 agonist exendin-4 reduces food intake in nonhuman primates through changes in meal size.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335926

Leptin and the control of food intake: neurons in the nucleus of the solitary tract are activated by both gastric distension and leptin.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335926

Liraglutide, a long-acting glucagon-like peptide-1 analog, reduces body weight and food intake in obese candy-fed rats, whereas a dipeptidyl peptidase-IV inhibitor, vildagliptin, does not.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335926

Leptin regulation of the anorexic response to glucagon-like peptide-1 receptor stimulation.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335926

Interim analysis of the effects of exenatide treatment on A1C, weight and cardiovascular risk factors over 82 weeks in 314 overweight patients with type 2 diabetes

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335926

Randomized trial of lifestyle modification and pharmacotherapy for obesity

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335926

Attenuation of lipopolysaccharide anorexia by antagonism of caudal brain stem but not forebrain GLP-1-R.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335926

Leptin amplifies the feeding inhibition and neural activation arising from a gastric nutrient preload.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335926

Divergent roles of SHP-2 in ERK activation by leptin receptors

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335926

Cholecystokinin and leptin act synergistically to reduce body weight

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3335926

The epidemiology of obesity

17 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FIJO.2011.265

[11C]MDL 100907, a radioligland for selective imaging of 5-HT(2A) receptors with positron emission tomography

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FIJO.2011.265

Increased feeding and hyperglycemia elicited by intracerebroventricular 5-thioglucose

21 January 2018

1 reference

12 December 2020

Distribution of GLP-1 binding sites in the rat brain: evidence that exendin-4 is a ligand of brain GLP-1 binding sites

1 reference

12 December 2020

Testing for synergism over a range of fixed ratio drug combinations: Replacing the isobologram

1 reference

12 December 2020

Interactions between leptin and exendin-4, a glucagon-like peptide-1 agonist, in the regulation of food intake in the rat

1 reference

12 December 2020

Effects of peripheral or central GLP-1 receptor blockade on leptin-induced suppression of appetite

1 reference

12 December 2020

Identifiers

DOI

10.1038/IJO.2011.265

1 reference

17 October 2017

1 reference

17 October 2017

1 reference