(Q42148578)

English

Novel inhibitors of the Pseudomonas aeruginosa virulence factor LasB: a potential therapeutic approach for the attenuation of virulence mechanisms in pseudomonal infection

scientific article published on 28 March 2011

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Novel inhibitors of the Pseudomonas aeruginosa virulence factor LasB: a potential therapeutic approach for the attenuation of virulence mechanisms in pseudomonal infection (English)

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Pseudomonas aeruginosa

object named as

Pseudomonas aeruginosa

1 reference

based on heuristic

inferred from title

author name string

George R A Cathcart

1

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Derek Quinn

2

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Brett Greer

3

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Pat Harriott

4

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

John F Lynas

5

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Brendan F Gilmore

6

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Brian Walker

7

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

language of work or name

0 references

publication date

28 March 2011

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Antimicrobial Agents and Chemotherapy

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

55

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

6

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

2670-2678

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

The estimation of the bactericidal power of the blood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Inhibitor profiling of the Pseudomonas aeruginosa virulence factor LasB using N-alpha mercaptoamide template-based inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Targeting QseC signaling and virulence for antibiotic development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Proteases and cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Airway inflammation in cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Multi-targeting by monotherapeutic antibacterials.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

The exopolysaccharide alginate protects Pseudomonas aeruginosa biofilm bacteria from IFN-gamma-mediated macrophage killing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Pseudomonas aeruginosa elastase disables proteinase-activated receptor 2 in respiratory epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Pathogen-host interactions in Pseudomonas aeruginosa pneumonia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Understanding bacterial biofilms in patients with cystic fibrosis: current and innovative approaches to potential therapies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Compromised Host Defense on Pseudomonas aeruginosa Biofilms: Characterization of Neutrophil and Biofilm Interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Bacterial protease inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Interactions between biocide cationic agents and bacterial biofilms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Conversion to mucoidy in Pseudomonas aeruginosa infecting cystic fibrosis patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Causes and effects of the chronic inflammation in venous leg ulcers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Secretion of nucleoside diphosphate kinase by mucoid Pseudomonas aeruginosa 8821: involvement of a carboxy-terminal motif in secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Bacterial proteinases as targets for the development of second-generation antibiotics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Solid-phase synthesis and biological screening of N-alpha-mercaptoamide template-based matrix metalloprotease inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

The Calgary Biofilm Device: new technology for rapid determination of antibiotic susceptibilities of bacterial biofilms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Mutational analysis of nucleoside diphosphate kinase from Pseudomonas aeruginosa: characterization of critical amino acid residues involved in exopolysaccharide alginate synthesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Protease cleavage of iron-transferrin augments pyocyanin-mediated endothelial cell injury via promotion of hydroxyl radical formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Iron release from transferrin by pyoverdin and elastase from Pseudomonas aeruginosa.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Investigation of ciprofloxacin penetration into Pseudomonas aeruginosa biofilms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

In vitro inhibition of Pseudomonas aeruginosa elastase by metal-chelating peptide derivatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

The effect of 2-mercaptoacetyl-L-phenylalanyl-L-leucine, a specific inhibitor of Pseudomonas aeruginosa elastase, on experimental Pseudomonas keratitis in rabbit eyes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Inhibition by phosphoramidon of Pseudomonas aeruginosa elastase injected intracorneally in rabbit eyes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Evaluation of Pseudomonas aeruginosa exotoxin A and elastase as virulence factors in acute lung infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Substrate specificity of elastolytic and nonelastolytic proteinases from Pseudomonas aeruginosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Extracellular toxins of Pseudomonas aeruginosa.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Role of Pseudomonas aeruginosa exoenzymes in lung infections of patients with cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Impact of proteases on iron uptake of Pseudomonas aeruginosa pyoverdin from transferrin and lactoferrin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Activation of hageman factor and prekallikrein and generation of kinin by various microbial proteinases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Pseudomonas aeruginosa alginate in cystic fibrosis sputum and the inflammatory response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Inhibition of Pseudomonas aeruginosa elastase and Pseudomonas keratitis using a thiol-based peptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Alginate synthesis by Pseudomonas aeruginosa: a key pathogenic factor in chronic pulmonary infections of cystic fibrosis patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

29 May 2018

Molecular insight into pseudolysin inhibition using the MM-PBSA and LIE methods.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

17 August 2018

Metalloproteases from Pseudomonas aeruginosa degrade human RANTES, MCP-1, and ENA-78.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

17 August 2018

Hemorrhagic activity and muscle damaging effect of Pseudomonas aeruginosa metalloproteinase (elastase).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

17 August 2018

A modified microtiter-plate test for quantification of staphylococcal biofilm formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

17 August 2018

Mucoid conversion of Pseudomonas aeruginosa by hydrogen peroxide: a mechanism for virulence activation in the cystic fibrosis lung.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

17 August 2018

Inactivation of human bronchial mucosal proteinase inhibitor by Pseudomonas aeruginosa elastase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101427

17 August 2018

alpha1-Antitrypsin inhalation reduces airway inflammation in cystic fibrosis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/21444693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of phosphoramidon on protection against corneal ulcer caused by elastase and protease from Pseudomonas aeruginosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/21444693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular function of elastase in Pseudomonas aeruginosa: role in the cleavage of nucleoside diphosphate kinase and in alginate synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21444693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinases, gelatinase and collagenase, in chronic leg ulcers

1 reference

https://pubmed.ncbi.nlm.nih.gov/21444693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of Pseudomonas aeruginosa elastase as a potent inflammatory factor in a rat air pouch inflammation model

1 reference

https://pubmed.ncbi.nlm.nih.gov/21444693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fibronectin degradation in chronic wounds depends on the relative levels of elastase, alpha1-proteinase inhibitor, and alpha2-macroglobulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/21444693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Permeation of antimicrobial agents through Pseudomonas aeruginosa biofilms: a simple method

1 reference

https://pubmed.ncbi.nlm.nih.gov/21444693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha 1-antitrypsin is degraded and non-functional in chronic wounds but intact and functional in acute wounds: the inhibitor protects fibronectin from degradation by chronic wound fluid enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21444693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PSEUDOMONAS AERUGINOSA ELASTASE. ISOLATION, CRYSTALLIZATION, AND PRELIMINARY CHARACTERIZATION

1 reference

https://pubmed.ncbi.nlm.nih.gov/21444693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elastase-producing Pseudomonas aeruginosa degrade plasma proteins and extracellular products of human skin and fibroblasts, and inhibit fibroblast growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/21444693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Degradation of antiproteinases, complement and fibronectin in chronic leg ulcers

1 reference

https://pubmed.ncbi.nlm.nih.gov/21444693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunization with a Pseudomonas aeruginosa elastase peptide reduces severity of experimental lung infections due to P. aeruginosa Or Burkholderia cepacia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21444693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Up-regulation of elastase in acute wounds of healthy aged humans and chronic venous leg ulcers are associated with matrix degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21444693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of Proteolytic Enzyme on Experimental Infection of Mice with Pseudomonas aeruginosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/21444693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.00776-10

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

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