(Q42148929)

17 October 2017

System x(c)- and thioredoxin reductase 1 cooperatively rescue glutathione deficiency (English)

1 reference

17 October 2017

Marcus Conrad

14

0 references

Georg W Bornkamm

13

object named as

Georg W Bornkamm

1 reference

17 October 2017

11

Peter Kuhlencordt

1 reference

17 October 2017

Pankaj Kumar Mandal

1

1 reference

17 October 2017

Alexander Seiler

2

1 reference

17 October 2017

Tamara Perisic

3

1 reference

17 October 2017

Pirkko Kölle

4

1 reference

17 October 2017

Ana Banjac Canak

5

1 reference

17 October 2017

Heidi Förster

6

1 reference

17 October 2017

Norbert Weiss

7

1 reference

17 October 2017

Elisabeth Kremmer

8

1 reference

17 October 2017

Michael W Lieberman

9

1 reference

17 October 2017

Shiro Bannai

10

1 reference

17 October 2017

Hideyo Sato

12

1 reference

17 October 2017

language of work or name

English

0 references

publication date

12 May 2010

1 reference

Journal of Biological Chemistry

17 October 2017

1 reference

17 October 2017

285

1 reference

17 October 2017

29

1 reference

17 October 2017

22244-22253

1 reference

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

17 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Membrane redox state and apoptosis: death by peroxide

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Small interfering RNA-mediated xCT silencing in gliomas inhibits neurodegeneration and alleviates brain edema.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Redox characteristics of the eukaryotic cytosol

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

The cystine/cysteine cycle: a redox cycle regulating susceptibility versus resistance to cell death

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

S-glutathionylation in protein redox regulation.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Mechanisms of reversible protein glutathionylation in redox signaling and oxidative stress

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Over expression of glutamate cysteine ligase increases cellular resistance to H2O2-induced DNA single-strand breaks

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Protein glutathionylation and oxidative stress

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Thioredoxin reductase 1 deficiency reverses tumor phenotype and tumorigenicity of lung carcinoma cells

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Redox imbalance in cystine/glutamate transporter-deficient mice

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Inhibition of cystine uptake disrupts the growth of primary brain tumors

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Regulation of protein function by glutathionylation

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Cytoplasmic thioredoxin reductase is essential for embryogenesis but dispensable for cardiac development

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Essential role for mitochondrial thioredoxin reductase in hematopoiesis, heart development, and heart function

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Activation of transcription factor Nrf-2 and its downstream targets in response to moloney murine leukemia virus ts1-induced thiol depletion and oxidative stress in astrocytes

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Glutaredoxins: glutathione-dependent redox enzymes with functions far beyond a simple thioredoxin backup system

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

The absence of mitochondrial thioredoxin 2 causes massive apoptosis, exencephaly, and early embryonic lethality in homozygous mice

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Glutathionylation of human thioredoxin: a possible crosstalk between the glutathione and thioredoxin systems

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Reactive oxygen species, antioxidants, and the mammalian thioredoxin system

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Role of the glutathione/glutaredoxin and thioredoxin systems in yeast growth and response to stress conditions.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Glutathione synthesis is essential for mouse development but not for cell growth in culture

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Cloning and expression of a plasma membrane cystine/glutamate exchange transporter composed of two distinct proteins

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

A glutathione reductase mutant of yeast accumulates high levels of oxidized glutathione and requires thioredoxin for growth

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Induction of cystine transport activity in mouse peritoneal macrophages by bacterial lipopolysaccharide

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Entamoeba histolytica: a eukaryote without glutathione metabolism.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Glutathione transferases--structure and catalytic activity

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Inhibition of amino acid transport into lymphoid cells by the glutamine analog L-2-amino-4-oxo-5-chloropentanoate

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Bovine thioredoxin system. Purification of thioredoxin reductase from calf liver and thymus and studies of its function in disulfide reduction

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

The role of the thioredoxin and glutaredoxin pathways in reducing protein disulfide bonds in the Escherichia coli cytoplasm.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Cysteine/cystine couple is a newly recognized node in the circuitry for biologic redox signaling and control

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Distribution of cystine/glutamate exchange transporter, system x(c)-, in the mouse brain.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Maturation of cytosolic iron-sulfur proteins requires glutathione

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Recycling of vitamin C by mammalian thioredoxin reductase

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Early embryonic lethality caused by targeted disruption of the mouse thioredoxin gene.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903358

Transport interaction of L-cystine and L-glutamate in human diploid fibroblasts in culture

17 August 2018

1 reference

12 December 2020

Rat liver thioredoxin and thioredoxin reductase: purification and characterization

1 reference

12 December 2020

Exchange of cystine and glutamate across plasma membrane of human fibroblasts

1 reference

12 December 2020

Reduction of the ascorbyl free radical to ascorbate by thioredoxin reductase

1 reference

12 December 2020

Visualization of ribonucleotide reductase catalytic oxidation establishes thioredoxins as its major reductants in yeast

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.121327

1 reference

17 October 2017

1 reference

17 October 2017

PubMed publication ID

20463017

1 reference