(Q42149374)

English

Ebselen attenuates oxidative stress-induced apoptosis via the inhibition of the c-Jun N-terminal kinase and activator protein-1 signalling pathway in PC12 cells

scientific article published on August 2002

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scholarly article

1 reference

Europe PubMed Central

17 October 2017

Ebselen attenuates oxidative stress-induced apoptosis via the inhibition of the c-Jun N-terminal kinase and activator protein-1 signalling pathway in PC12 cells (English)

1 reference

Europe PubMed Central

17 October 2017

author name string

Masanori Yoshizumi

1

1 reference

Europe PubMed Central

17 October 2017

Toshiaki Kogame

2

1 reference

Europe PubMed Central

17 October 2017

Yuki Suzaki

3

1 reference

Europe PubMed Central

17 October 2017

Yoshiko Fujita

4

1 reference

Europe PubMed Central

17 October 2017

Moe Kyaw

5

1 reference

Europe PubMed Central

17 October 2017

Kazuyoshi Kirima

6

1 reference

Europe PubMed Central

17 October 2017

Keisuke Ishizawa

7

1 reference

Europe PubMed Central

17 October 2017

Koichiro Tsuchiya

8

1 reference

Europe PubMed Central

17 October 2017

Shoji Kagami

9

1 reference

Europe PubMed Central

17 October 2017

Toshiaki Tamaki

10

1 reference

Europe PubMed Central

17 October 2017

language of work or name

0 references

publication date

1 August 2002

1 reference

Europe PubMed Central

17 October 2017

British Journal of Pharmacology

1 reference

Europe PubMed Central

17 October 2017

136

1 reference

Europe PubMed Central

17 October 2017

7

1 reference

Europe PubMed Central

17 October 2017

1023-1032

1 reference

Europe PubMed Central

17 October 2017

Reactive oxygen species as mediators of signal transduction in cardiovascular disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

Antioxidants inhibit JNK and p38 MAPK activation but not ERK 1/2 activation by angiotensin II in rat aortic smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

Signal transduction of reactive oxygen species and mitogen-activated protein kinases in cardiovascular disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

Reactive oxygen radicals in signaling and damage in the ischemic brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

c-Jun and the transcriptional control of neuronal apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

Apoptotic and antiapoptotic mechanisms in stroke.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

Alteration of MAP kinase pathways after transient forebrain ischemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

Neuroprotection by MAPK/ERK kinase inhibition with U0126 against oxidative stress in a mouse neuronal cell line and rat primary cultured cortical neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

Src and Cas mediate JNK activation but not ERK1/2 and p38 kinases by reactive oxygen species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

c-Jun triggers apoptosis in human vascular endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

Delayed neuronal cell death in the rat hippocampus is mediated by the mitogen-activated protein kinase signal transduction pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

Induction of apoptosis in HEp-2 cells by infection with herpes simplex virus type 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

Hydrogen peroxide activation of multiple mitogen-activated protein kinases in an oligodendrocyte cell line: role of extracellular signal-regulated kinase in hydrogen peroxide-induced cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

Effect of endothelin-1 (1-31) on extracellular signal-regulated kinase and proliferation of human coronary artery smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

Lasting N-terminal phosphorylation of c-Jun and activation of c-Jun N-terminal kinases after neuronal injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

A splicing variant of a death domain protein that is regulated by a mitogen-activated kinase is a substrate for c-Jun N-terminal kinase in the human central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

Role of the Jun kinase pathway in the regulation of c-Jun expression and apoptosis in sympathetic neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

Ebselen in acute ischemic stroke: a placebo-controlled, double-blind clinical trial. Ebselen Study Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

Neuroprotective efficacy of ebselen, an anti-oxidant with anti-inflammatory actions, in a rodent model of permanent middle cerebral artery occlusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

AP-1 function and regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

Sounding the alarm: protein kinase cascades activated by stress and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

Role of oxidants in ischemic brain damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

Oxygen radicals in focal cerebral ischemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

How MAP kinases are regulated

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

Measurement of striatal H2O2 by microdialysis following global forebrain ischemia and reperfusion in the rat: correlation with the cytotoxic potential of H2O2 in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

Cell death: the significance of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

Kinetic mechanism and substrate specificity of glutathione peroxidase activity of ebselen (PZ51).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

George E. Brown memorial lecture. Oxygen radicals in cerebral vascular injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

Inhibition of superoxide anion production in guinea pig polymorphonuclear leukocytes by a seleno-organic compound, ebselen.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

29 May 2018

https://pubmed.ncbi.nlm.nih.gov/12145102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ebselen reduces cytochrome c release from mitochondria and subsequent DNA fragmentation after transient focal cerebral ischemia in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

17 August 2018

Simulation of multiple isotropic spin-trap EPR spectra.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

17 August 2018

Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573436

17 August 2018

A novel biologically active seleno-organic compound--II. Activity of PZ 51 in relation to glutathione peroxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12145102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of ebselen (PZ51) on ischaemic brain oedema after focal ischaemia in cats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12145102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotective effect of alpha-phenyl-N-tert-butylnitrone in gerbil hippocampus is mediated by the mitogen-activated protein kinase pathway and heat shock proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/12145102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactive oxygen species mediate cytokine activation of c-Jun NH2-terminal kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12145102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Implication of radical oxygen species in ceramide generation, c-Jun N-terminal kinase activation and apoptosis induced by daunorubicin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12145102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neuroprotective efficacy of ebselen (a glutathione peroxidase mimic) on brain damage induced by transient focal cerebral ischaemia in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/12145102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The reaction of ebselen with peroxynitrite

1 reference

https://pubmed.ncbi.nlm.nih.gov/12145102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel biologically active seleno-organic compound--V. Inhibition by ebselen (PZ 51) of rat peritoneal neutrophil lipoxygenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12145102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential activation of MAPK/ERK and p38/SAPK in neurones and glia following focal cerebral ischaemia in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/12145102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/12145102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Doxorubicin-induced apoptosis in endothelial cells and cardiomyocytes is ameliorated by nitrone spin traps and ebselen. Role of reactive oxygen and nitrogen species

1 reference

https://pubmed.ncbi.nlm.nih.gov/12145102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel biologically active seleno-organic compound—1

1 reference

https://pubmed.ncbi.nlm.nih.gov/12145102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelin-1 and smooth muscle cells: induction of jun amino-terminal kinase through an oxygen radical-sensitive mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/12145102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selenoorganic compound, ebselen, inhibits nitric oxide and tumor necrosis factor-alpha production by the modulation of jun-N-terminal kinase and the NF-kappab signaling pathway in rat Kupffer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12145102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJP.0704808

1 reference

Europe PubMed Central

17 October 2017

1 reference

Europe PubMed Central

17 October 2017

1 reference

Europe PubMed Central

17 October 2017

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0 references

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